Navigation Links
A 'jumping gene's' preferred targets may influence genome evolution
Date:9/6/2011

Baltimore, MD The human genome shares several peculiarities with the DNA of just about every other plant and animal. Our genetic blueprint contains numerous entities known as transposons, or "jumping genes," which have the ability to move from place to place on the chromosomes within a cell.

An astounding 50% of human DNA comprises both active transposon elements and the decaying remains of former transposons that were active thousands to millions of years ago before becoming damaged and immobile. If all of this mobile and formerly mobile DNA were not mysterious enough, every time a plant, animal or human cell prepares to divide, the chromosome regions richest in transposon-derived sequences, even elements long deceased, are among the last to duplicate. The reason for their delayed duplication, if there is one, has eluded biologists for more than 50 years.

New research led by Carnegie's Allan Spradling and published online this week by Proceedings of the National Academy of Sciences provides potential insight into both these enigmas.

The scientists used the fruit fly, Drosophila melanogaster, one of the premier "model" organisms for studying genome structure and gene function. They focused on one particular transposon, called the P element, which has an unsurpassed ability to move that has stimulated its widespread use by Drosophila researchers.

Remarkably, P elements have only been present in Drosophila melanogaster for about 80 years, at which time they were acquired from the genome of a distantly related fruit fly species by an unknown process. P elements remain highly "infective" today. Adding just one copy to the genome of one fly causes all the flies in a laboratory population with which it breeds to acquire 30 to 50 P elements within a few generations. The original goal of the Spradling team's research was not to understand how transposons spread or genomes evolve, but something much simpler: To l
'/>"/>

Contact: Allan Spradling
spradling@ciwemb.edu
410-246-3021
Carnegie Institution
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. The informant: a jumping gene
2. David and Goliath viruses shed light on the origin of jumping genes: UBC study
3. Discovery of jumping gene cluster tangles tree of life
4. Johns Hopkins researchers capture jumping genes
5. Jumping genes find new homes in humans more often than previously thought
6. Jumping genes provide extensive raw material for evolution, Penn study finds
7. The genetic secrets to jumping the species barrier
8. New data suggest jumping genes play a significant role in gene regulatory networks
9. McMaster researchers find missing genes may separate coach potato from active cousin
10. Parents stress leaves lasting marks on children’s genes: UBC-CFRI research
11. How an evolutionary playground brings plant genes together
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2015)... 2015  VOXX International Corporation (Nasdaq: VOXX ... a Definitive Agreement to purchase the assets, inclusive ... leader EyeLock through an acquiring entity.  Upon consummation ... interest in the acquiring entity. The closing of ... diligence.  Expanding on its existing supply chain and ...
(Date:8/12/2015)... Florida , August 12, 2015 ... pace of mobile payment innovation and advanced biometrics technology ... replace the way consumers rely on using their credit ... with reinventing the future for payment services led by ... NXTD ), :  Google, Inc. (NASDAQ: GOOG ...
(Date:8/10/2015)... August 10, 2015 The latest 364 ... comprehensive analysis of the global border security market . ... of $16.4bn in 2015. Now: Border security is ... example of the business critical issue you need to know ... visiongain ,s objective analysis of how this will impact your ...
Breaking Biology News(10 mins):VOXX International Corporation Signs Definitive Agreement To Acquire The Assets And A Controlling Interest Of Biometric Leader EyeLock 2VOXX International Corporation Signs Definitive Agreement To Acquire The Assets And A Controlling Interest Of Biometric Leader EyeLock 3VOXX International Corporation Signs Definitive Agreement To Acquire The Assets And A Controlling Interest Of Biometric Leader EyeLock 4VOXX International Corporation Signs Definitive Agreement To Acquire The Assets And A Controlling Interest Of Biometric Leader EyeLock 5Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 2Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 3Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 4Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 5Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 6Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 2Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 3Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 4Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 5Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 6Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 7Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 8Border Security Market Report 2015-2025 - Growth in Biometrics, ICT, Manned and Unmanned Vehicles, and Perimeter Surveillance 9
... A common antipsychotic drug used in emergency rooms to ... of the brain known to regulate movement, a new ... rats, indicate that only the combination of the medication, ... one alone. Senior author Bryan Yamamoto, PhD, and his ...
... the U.S. government’s watershed decision to propose listing the ... the Wildlife Conservation Society (WCS) is launching a bold ... by following the bears themselves, but the receding sea ... of global warming. In a project named "Warm Waters ...
... meaning to watching out for other mothers' kids. , ... by the University of Alberta in Edmonton, Canada and the ... responded to the recorded distress calls of fawns, similar to ... mothers responding to both whitetail and mule deer calls, even ...
Cached Biology News:Common treatment for methamphetamine overdose may damage brain cells 2Want to save polar bears? Follow the ice 2Want to save polar bears? Follow the ice 3Mule deer moms rescue other fawns 2
(Date:8/31/2015)... GUELPH, ON , Aug. 31, 2015 /PRNewswire/ - BIOREM ... new orders totalling $5.7 million. The orders are for air emission ... "Of particular note is a large order for a ... our equipment will be replacing a competitor,s system that failed ... see in our engineered solutions," said Derek S. Webb ...
(Date:8/31/2015)... Aug. 31, 2015 Research and Markets ( ... "Israel Biomedical Sensors Market - Growth, Trends & Forecasts ... The Israel Biomedical Sensors market is estimated at $0.19 ... the period 2014-2020 The near future will ... formulation of each individual. These sensors can be set ...
(Date:8/31/2015)... 31, 2015  US-Australian drug discovery company, Novogen ... confirmed its comprehensive scientific review has identified high ... areas of unmet patient need. Novogen is moving ... projects prior to entering into Phase 1 clinical ... Acting Chief Executive Officer, Iain Ross , ...
(Date:8/31/2015)... ... August 31, 2015 , ... Regulatory ... in the drug development approval process. Thus, innovator companies must understand what will ... Inc., a Chicago-based CMO, has been hosting multiple educational panels and seminars for ...
Breaking Biology Technology:Israel Biomedical Sensors Market 2015 - Growth, Trends & Forecasts to 2020 2Novogen Announces The Outcome Of A Comprehensive Science Review 2Novogen Announces The Outcome Of A Comprehensive Science Review 3Novogen Announces The Outcome Of A Comprehensive Science Review 4Novogen Announces The Outcome Of A Comprehensive Science Review 5Novogen Announces The Outcome Of A Comprehensive Science Review 6Regis Shares Expert Advice on Impurities in Drug Development 2Regis Shares Expert Advice on Impurities in Drug Development 3
... and PARSIPPANY, N.J., Sept. 29, DSM Biologics and ... today that the high-titer fed-batch process,developed at the ... USA was recently scaled up to 250 liters ... Groningen, The Netherlands. They,successfully achieved 8 grams per ...
... (NYSE:,CVD) announced today that it will no longer ... provide preclinical contract research services in,China., "We ... outsourced drug,development services over the longer-term. To seize ... build our own world-class preclinical,facility in the region ...
... Dr. Qi Lu, former EVP of,Yahoo!, continues to dedicate ... president of HYSTA, USA. HYSTA is greatly,honored to have Qi,s ... end of August, he had served more than 10,years, which ... one thing that has not changed is his dedication to ...
Cached Biology Technology:DSM and Crucell Announce Another Key Achievement for PER.C6(R) Technology; Scale Up of High-Titer Fed-Batch Process to 250 Liters 2DSM and Crucell Announce Another Key Achievement for PER.C6(R) Technology; Scale Up of High-Titer Fed-Batch Process to 250 Liters 3DSM and Crucell Announce Another Key Achievement for PER.C6(R) Technology; Scale Up of High-Titer Fed-Batch Process to 250 Liters 4Covance Decides to Pursue Its Original Preclinical Strategy in China 2Update: HYSTA Announces Dr. Qi Lu to Continue on as President of HYSTA, USA 2
Mouse monoclonal to OCIL ( Abpromise for all tested applications)....
... GenBank Accession Number : NM_201222 ... corresponding to amino acids 161-176 ... antiserum in 0.05% sodium azide ... routinely evaluated by immunoblot on ...
The FailSafe™ PROBES Real-Time PCR System enables rapid, precise optimization of PCR experiments in which the product is detected using fluorescent target-specific labeled probes....
Immunofixation Gel Kit, requires IF100 Reactivity: Human Applications: Immunofixation ...
Biology Products: