Navigation Links
A hijacking of healthy cellular circuits
Date:4/8/2013

ticipate.

When they are, however, they can illuminate novel therapeutic strategies. Mischel and Bensinger's team found, for example, that both glioblastoma cell cultures derived from patients and tumors transplanted into mice were potently suppressed when both receptors were blocked at once. "This suggests that if you target both receptors," says Mischel, "you might be able to prevent drug resistance."

Though the study led by Mischel and Bensinger focuses on glioblastoma, its findings are relevant to many other cancersand not just because aberrant EGFR signaling drives the growth of many types of tumors.

The next step, Mischel says, is to test in clinical trials how targeting both receptors affects the treatment of glioblastoma. He and his colleagues also hope to work with other Ludwig researchers to explore small molecule inhibitors of PDGFRβ and to examine whether similar drug resistance mechanisms are found in other cancers as well.


'/>"/>

Contact: Rachel Steinhardt
rsteinhardt@licr.org
212-450-1582
Ludwig Institute for Cancer Research
Source:Eurekalert

Page: 1 2 3

Related biology news :

1. Horticultural hijacking
2. To drive infections, a hijacking virus mimics a cells signaling system
3. Unhealthy eating can make a bad mood worse
4. Stronger support needed for healthy beverage practices in child care
5. Neuronal activity induces tau release from healthy neurons
6. Building healthy bones takes guts
7. Healthy seeds -- treated environmentally friendly
8. Poor mental health leads to unhealthy behaviors among low-income adults
9. Foods identified as whole grain not always healthy
10. UC Davis study deflates notion that pear-shaped bodies more healthy than apples
11. R U eating healthy 2day?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/18/2015)... 18, 2015 Fingerprint Cards (FPC) has ... FPC1145, FPC1155 and FPC1035 from one if its module partners. ... including Q3 2015 and the sensors will be used by ... values for 2015 hereby amount to 740 MSEK to date. ... 140 MSEK and a number of smaller orders not separately ...
(Date:5/11/2015)... Ohio , May 11, 2015  Through a well-rounded ... Ohio had a strong showing at AUVSI,s Unmanned ... These representatives of Ohio,s UAS industry ... and abroad from all points along the UAS ecosystem. ... Development Coalition,s (DDC) Vice President for Aerospace Rich Knoll ...
(Date:5/7/2015)... , May 7, 2015 ... sensors, FPC1022 and FPC1035, FPC,s smallest touch fingerprint ... are mainly considered for integration on the backside ... smartphone OEMs increased possibilities to integrate touch fingerprint ... size also improves possibilities for module manufacturers to ...
Breaking Biology News(10 mins):Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 230 Million and Raises Revenue Guidance for 2015 2Ohio Flies High at Unmanned '15, Sets Stage for Ohio UAS Conference 2FPC Introduces its Smallest Touch Fingerprint Sensors to Date 2
... available in Spanish . Studies by ... presence of Escherichia coli pathogens in surface waters ... in underwater sediments. Most E. coli strains ... water quality managers to estimate fecal contamination. These findings, ...
... of years ago, humans discovered flammable gas could be produced ... anaerobic digestion. Today, EU laws are pushing governments to use ... to enrich soil or biogas for energy. Our environment would ... dumped in diminishing landfill sites. However, while the scientific ...
... have filled an important gap in the study of tunicate ... gelatinous, free-swimming types of tunicates. Their study was featured on ... of Plankton Research . Tunicates are a phylum of ... covering called a tunic, from which the name derives. ...
Cached Biology News:E. coli can survive in streambed sediments for months 2Time to make more out of waste 2Time to make more out of waste 3Woods Hole Oceanographic Institution study sheds light on tunicate evolution 2
(Date:5/21/2015)... May 21, 2015  CytRx Corporation (NASDAQ: ... specializing in oncology, today announced positive updated results ... aldoxorubicin for the treatment of unresectable glioblastoma multiforme ... open-label, multisite trial is designed to investigate the ... whose tumors have progressed following prior treatment with ...
(Date:5/21/2015)... DUBLIN , May 20, 2015 Research ... announced the addition of the "2015 Global ... to their offering. The primary goal ... of flow cytometry instruments and reagents. Key information ... drive the selection of flow cytometers, predominantly used ...
(Date:5/21/2015)... Kingston, Ontario (PRWEB) May 21, 2015 ... entered into an exclusive North American distribution agreement ... microbiology testing system. , With more than 160 ... of products and services for laboratory and production ... choice, operational excellence and differentiated services to enable ...
(Date:5/20/2015)... Calif. , May 20, 2015 ... today presented preliminary data demonstrating the ability of ... pulmonary fibrosis (IPF) from other interstitial lung diseases ... suggest the classifier,s potential to help thousands of ... resolve ambiguity in IPF diagnosis – a frequent ...
Breaking Biology Technology:CytRx Reports Positive Updated Phase 2 Aldoxorubicin Clinical Trial Results in Glioblastoma Multiforme (Brain Cancer) 2CytRx Reports Positive Updated Phase 2 Aldoxorubicin Clinical Trial Results in Glioblastoma Multiforme (Brain Cancer) 3CytRx Reports Positive Updated Phase 2 Aldoxorubicin Clinical Trial Results in Glioblastoma Multiforme (Brain Cancer) 4CytRx Reports Positive Updated Phase 2 Aldoxorubicin Clinical Trial Results in Glioblastoma Multiforme (Brain Cancer) 5CytRx Reports Positive Updated Phase 2 Aldoxorubicin Clinical Trial Results in Glioblastoma Multiforme (Brain Cancer) 6CytRx Reports Positive Updated Phase 2 Aldoxorubicin Clinical Trial Results in Glioblastoma Multiforme (Brain Cancer) 7Global Survey on Flow Cytometry Adoption Trends 2015 2Veolia’s TECTA™ B16 Instrument for E. Coli Detection is Offered Exclusively Through VWR 2Veracyte Presents Preliminary Data Demonstrating Ability of Molecular Classifier to Improve Non-Surgical IPF Diagnosis Using Bronchoscopy Samples 2Veracyte Presents Preliminary Data Demonstrating Ability of Molecular Classifier to Improve Non-Surgical IPF Diagnosis Using Bronchoscopy Samples 3Veracyte Presents Preliminary Data Demonstrating Ability of Molecular Classifier to Improve Non-Surgical IPF Diagnosis Using Bronchoscopy Samples 4Veracyte Presents Preliminary Data Demonstrating Ability of Molecular Classifier to Improve Non-Surgical IPF Diagnosis Using Bronchoscopy Samples 5
... Data presented today at the 19th Congress of ... demonstrated that the HeartWare MVAD ® Pump ... biocompatibility in Good Laboratory Practice (GLP) animal studies, ... clinical studies. (Photo:   http://photos.prnewswire.com/prnh/20110909/LA65433 ...
... (NSF) has awarded Northwestern University a six-year, $16.2 million ... Engineering Center (MRSEC), one of the oldest interdisciplinary research ... integrates educational activities with a scientific research program, is ... in the nation to successfully renew support from the ...
... 8, 2011 HUYA Bioscience International, ... announced a strategic partnership with the Zhejiang Chinese ... will accelerate the global drug development of China,s ... partnership is expected to bring productive synergy between ...
Cached Biology Technology:HeartWare Completes GLP Studies of Next Generation MVAD® Pump; Data Presented Today at ISRBP Congress 2HeartWare Completes GLP Studies of Next Generation MVAD® Pump; Data Presented Today at ISRBP Congress 3HeartWare Completes GLP Studies of Next Generation MVAD® Pump; Data Presented Today at ISRBP Congress 4Collaborative science and engineering 2HUYA Bioscience International Forms Alliance With Zhejiang Chinese Medical University Life Science College 2HUYA Bioscience International Forms Alliance With Zhejiang Chinese Medical University Life Science College 3
... The Gene Pulser Xcell ... V, 50-60 Hz, is used ... This system includes the main ... (25-3,275 microfarad range) or square-wave ...
AVOID FREEZE/THAW CYCLES. Recognizes the ~5 kDa thymosin beta4 protein....
... Accurate To score SNPs, ... sequencing, the gold standard in DNA analysis. ... The polymorphic locus can be confirmed by ... DNA sequencing also provides sequence context information, ...
... PowerPac basic power supply are used for submerged ... gels. The mini format cell includes a buffer ... bubble. The PowerPac basic power supply, 100-120 and ... mA, and 75 W. Power cord and instructions ...
Biology Products: