Navigation Links
A high protein diet and meal replacements can reduce rebound weight gain

New research shows that there are several effective strategies available to people wanting to avoid regaining weight after a successful diet. Anti-obesity drugs, meal replacements and a high protein diet can help weight loss maintenance, according to a meta-analysis published in the scientific periodical The American Journal of Clinical Nutrition.

The study, which was carried out by researchers at Karolinska Institutet's Clinical Epidemiology Unit and the Obesity Centre at Karolinska University Hospital in Sweden, contributes knowledge about what is without doubt the greatest challenge to anyone attempting to lose weight: how to reduce rebound weight gain and maintain the lower body weight after the weight loss phase.

"The body has several defence mechanisms against weight loss, such as increased hunger, lower energy metabolism and relapse back to old habits," says research team member Dr Erik Hemmingsson. "If the problem of rebound weight gain didn't exist, obesity would be relatively easy to treat. There have been several possible methods to facilitate long-term weight control over the years, and now the database was large enough to make a systematic evaluation of existing studies."

In their meta-analysis, the team combined the results of 20 published scientific studies including a total of 3,017 participants, who were either obese or overweight at the start of the weight loss process. The various studies examined the effects of drugs, meal replacements, high protein diets, dietary supplements and exercise on rebound weight gain after an intensive weight loss, low-calorie diet (less the 1,000 calories a day).

Even though the study shows that rebound weight gain is more the rule than the exception, the researchers found that several strategies obviously helped to reduce the unwanted effect: anti-obesity drugs, powdered meal replacements, and a high protein diet. Low glycaemic index (GI) food was also effective, although the data in that case came from a single study, which the researchers say makes the conclusions less reliable.

"Anti-obesity drugs unfortunately carry a risk of adverse events, so the most effective drugs were completely withdrawn a few years ago," says Dr Hemmingsson. "Meal replacement products and high protein diets, on the other hand, are effective and available to everyone."

One interesting result was that exercise had no clear effect on weight loss maintenance. The reason, however, might be that one of the included trials studied relatively sick patients with serious arthrosis who had been prescribed special physiotherapy. In another study, in which the participants exercised in a more normal way, the effect was similar to eating a high protein diet. Dietary supplements were not associated with a reduced rebound effect.


Contact: Press Office
Karolinska Institutet

Related biology news :

1. Absence of the SMG1 protein could contribute to Parkinsons and other neurological disorders
2. How problems with an Alzheimers protein can jam up traffic in the brain
3. Proteins in one of the worlds main biodiesel plants have been mapped -- and it does not look good
4. Samurai sword protein makes strategic cuts in cell skeletons
5. Molecular biology: Designer of protein factories exposed
6. Berkeley Lab researchers get a detailed look at a DNA repair protein in action
7. Researchers capture images of open channel that moves proteins across cell membranes
8. A protein safeguards against cataracts
9. The yin and yang in the life of proteins
10. Zinc, proteins, and an essential cellular balancing act
11. Erratic proteins: New insights into a transport mechanism
Post Your Comments:
Related Image:
A high protein diet and meal replacements can reduce rebound weight gain
(Date:10/29/2015)... , Oct. 29, 2015  Connected health pioneer, ... driving the explosion of technology-enabled health and wellness, and ... new book, The Internet of Healthy Things ... sensors or smartphones even existed, Dr. Kvedar, vice president, ... of health care delivery, moving care from the hospital ...
(Date:10/27/2015)... Synaptics Inc. (NASDAQ: SYNA ), the leader ... adopted the Synaptics ® ClearPad ® Series ... newest flagship smartphones, the Nexus 5X by LG and ... --> --> Synaptics works closely with ... in the joint development of next generation technologies. Together, ...
(Date:10/23/2015)... BERLIN and GOLETA, California ... the HFES conference, BIOPAC and SensoMotoric Instruments (SMI) announce ... and eye tracking data captured during interactive real-world tasks ... plug and play integration of their established wearable solutions ... researchers to synchronize gaze behavior captured with SMI ...
Breaking Biology News(10 mins):
(Date:11/25/2015)... 2015 /PRNewswire/ - Aeterna Zentaris Inc. (NASDAQ:  AEZS; TSX: ... prospects remain fundamentally strong and highlights the following ... received DSMB recommendation to continue the ZoptEC Phase ... the final interim efficacy and safety data ... men with heavily pretreated castration- and Taxane-resistant prostate ...
(Date:11/24/2015)... 2015  Asia-Pacific (APAC) holds the third-largest share ... The trend of outsourcing to low-cost locations is ... volume share for the region in the short ... in the CRO industry will improve. ... ), finds that the market earned revenues ...
(Date:11/24/2015)... , ... November 24, 2015 , ... ... healthy metabolism. But unless it is bound to proteins, copper is also toxic ... (NIH), researchers at Worcester Polytechnic Institute (WPI) will conduct a systematic study of ...
(Date:11/24/2015)... ... ... This fall, global software solutions leader SAP and AdVenture Capital brought together ... their BIG ideas to improve health and wellness in their schools. , Now, the ... title of SAP's Teen Innovator, an all-expenses paid trip to Super Bowl 50, and ...
Breaking Biology Technology: