Navigation Links
A first: Nuclear transfer to reprogram adult patient cells into stem cells
Date:5/5/2014

Jerusalem, May 4, 2014 -- The capacity to reprogram adult patient cells into pluripotent, embryonic-like, stem cells by nuclear transfer has been reported as a breakthrough by scientists from the US and the Hebrew University of Jerusalem.

The work, described in the journal Nature, was accomplished by researchers from the New York Stem Cell Foundation Research Institute and Columbia University and by Nissim Benvenisty, the Herbert Cohn professor of Cancer Research and director of the Stem Cell Unit at the Institute of Life Sciences at the Hebrew University of Jerusalem, and his graduate student Ido Sagi. The latter assisted in the characterization of the pluripotent nature of these cells.

Pluripotency means the ability of stem cells to develop into all the cells of our body, including those in the brain, heart, liver and blood. In 2012, the Nobel Prize in Physiology or Medicine was awarded for two discoveries showing that mature (differentiated) cells can be converted into pluripotent, embryonic-like cells, either by forced expression of genetic factors or by transfer of cell nuclei into female eggs, in a process called "reprogramming."

However, the actual ability to reprogram cells from humans by nuclear transfer had only been accomplished until now by using fetal cells for this purpose, until this latest work involving reprogramming of adult patient cells demonstrated by the researchers from the US and the Hebrew University, as described in the new Nature article.

Future research should allow further characterization of these novel, pluripotent cell types and their comparison to other stem cells. "Human pluripotent stem cells generated from adult cells may change the face of medicine," says Prof. Benvenisty, leading to totally new, personalized genetic therapy involving the reprograming of a patient's own cells to achieve cell replacement and healing.


'/>"/>

Contact: Jerry Barach
jerryb@savion.huji.ac.il
972-258-82904
The Hebrew University of Jerusalem
Source:Eurekalert  

Page: 1

Related biology news :

1. Nice organisms finish first: Why cooperators always win in the long run
2. New paper by Notre Dame researchers describes method for cleaning up nuclear waste
3. Report presents designs for study of cancer risks near US nuclear facilities
4. Dartmouth scientists track radioactive iodine from Japan nuclear reactor meltdown
5. Postpone the nuclear waste decision
6. Autologous bone marrow-derived mononuclear cell transplants can reduce diabetic amputations
7. Researchers at GW receive federal funds to study the effect earthquakes have on nuclear reactors
8. Where to put nuclear waste?
9. Nuclear weapons surprising contribution to climate science
10. Stanford researchers calculate global health impacts of the Fukushima nuclear disaster
11. Fueling nuclear power with seawater
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
A first: Nuclear transfer to reprogram adult patient cells into stem cells
(Date:4/5/2017)... April 5, 2017  The Allen Institute for Cell ... Explorer: a one-of-a-kind portal and dynamic digital window into ... data, the first application of deep learning to create ... cell lines and a growing suite of powerful tools. ... these and future publicly available resources created and shared ...
(Date:4/5/2017)... KEY FINDINGS The global market for stem ... 25.76% during the forecast period of 2017-2025. The rise ... growth of the stem cell market. Download ... The global stem cell market is segmented on the ... cell market of the product is segmented into adult ...
(Date:4/3/2017)... 2017  Data captured by IsoCode, IsoPlexis ... a statistically significant association between the potency ... and objective response of cancer patients post-treatment. ... whether cancer patients will respond to CAR-T ... as to improve both pre-infusion potency testing and ...
Breaking Biology News(10 mins):
(Date:5/18/2017)... , ... May 18, 2017 , ... When James Sherley, was notified earlier this year ... Valuable Brands for the Year 2017 by The Silicon Review , he was not ... good progress increasing Asymmetrex’s value, but this recognition by Silicon Valley was particularly meaningful. ...
(Date:5/16/2017)... May 16, 2017 Telehealth has long ... and something that has been kept completely separate ... But according to   Logicalis Healthcare Solutions , ... IT solutions and managed services provider ( www.us.logicalis.com ... overlooked – interrelationship between telehealth, imaging, and EHR ...
(Date:5/15/2017)... ... 2017 , ... Algenist is continuing to disrupt the skincare ... with a patented formula, clinically proven to deliver visible firming results in 10 ... to our already innovative ELEVATE product line,” said vice president of product development ...
(Date:5/11/2017)... BOTHELL, Wash. , May 11, 2017   BioLife ... developer, manufacturer and marketer of proprietary clinical grade cell and ... media ("BioLife" or the "Company"), today reported operational highlights and ... Revenue from biopreservation media product sales reached a new high ... increase of 28% over the same period in 2016. Revenue ...
Breaking Biology Technology: