Navigation Links
A deeper look into the pathogen responsible for crown gall disease in plants
Date:7/10/2012

Next week's Journal of Biological Chemistry "Paper of the Week" by Wai Mun Huang and colleagues at the University of Utah Health Sciences Center and the University of Minnesota reveals new insights into the molecular properties of the rod-shaped soil bacterium Agrobacterium tumefaciens, the pathogen responsible for crown gall disease, a tumor-forming infection in plants, such as tomatoes, walnuts, grapes and beets.

The bacterium is parasitic: It infects its plant host by entering through an open wound, inserts a small segment of its genetic code into the plant's genome, devours energy made by the plant, and forms knobby brown lesions on the plant stem.

Huang's group focused on the pathogen's genetic material. Most bacteria have circular chromosomes. But A. tumefaciens C58, the strain studied by Huang's group, contains one circular chromosome and one linear chromosome (along with two circular plasmids). Huang's research illuminates how this bacterium maintains its linear chromosome.

Huang's team ascertained the DNA sequence for the telomeres, or the protective end caps, of the linear chromosome in A. tumefaciens C58 and confirmed that an enzyme, TelA, actually forms them by making hairpin loops. These end caps are important for maintaining the stability of linear chromosomes. Interestingly, TelA also binds the telomeres. This activity is unique among bacterial enzymes of this kind and may protect the telomeres (which degrade over time and thus lose their ability to preserve DNA), as telomere binding proteins do in eukaryotes.

"Hairpin-ended linear chromosomes and plasmids are found in a number of branches of bacteria and viruses," Huang says. "They are simple and elegant to form and to maintain." But what remains to be understood is why this linear configuration is not more common or even the preferred configuration for bacteria, Huang emphasizes.


'/>"/>

Contact: Angela Hopp
ahopp@asbmb.org
240-283-6614
American Society for Biochemistry and Molecular Biology
Source:Eurekalert

Page: 1

Related biology news :

1. Wind pushes plastics deeper into oceans, driving trash estimates up
2. Preserved frogs hold clues to deadly pathogen
3. Antitoxin strategy may help target other pathogens
4. College students work to sterilize air, kill pathogens on buses
5. Bees self-medicate when infected with some pathogens
6. Researchers uncover molecular pathway through which common yeast becomes fungal pathogen
7. New research finds increased growth responsible for color changes in coral reefs
8. Sports and energy drinks responsible for irreversible damage to teeth
9. Fertilizer use responsible for increase in nitrous oxide in atmosphere
10. Symposium: Protein-Folding Diseases: Models & Mechanisms
11. Small molecule may play big role in Alzheimers disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/26/2015)... May 26, 2015 Research ... addition of the "Saudi Arabia Biometric Systems ... their offering. ,     (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , ,The biometric ... is projected to grow at over 22% ... is attributed to the surging demand for better ...
(Date:5/22/2015)... , May 22, 2015  NXT-ID, Inc. (NASDAQ: ... 1st, it will be ending its promotional pricing and making ... Laurence Savin , Head of Marketing said, ... promotional pricing until the end of May. To get your ... and when we open the store on June 1, you,ll ...
(Date:5/21/2015)... -- According to a new market ... Services), by Applications (Surveillance (Airborne, Maritime, Land), Threat ... & Defense & Commercial) - Global Forecast to ... expected to grow from $7252.0 Million in 2015 ... Annual Growth Rate (CAGR) of 6.6%. ...
Breaking Biology News(10 mins):Saudi Arabia Biometric Systems Market Forecast and Opportunities, 2020 with Morpho Safran, ZK Technlogy, and Suprema Dominating 2NXT-ID, Inc Announces Retail Price For Wocket Smart Wallet And Extends Discounted Promotional Price Till End Of May 2NXT-ID, Inc Announces Retail Price For Wocket Smart Wallet And Extends Discounted Promotional Price Till End Of May 3Thermal Imaging Market Worth $9,998.9 Million by 2020 2Thermal Imaging Market Worth $9,998.9 Million by 2020 3Thermal Imaging Market Worth $9,998.9 Million by 2020 4
... Physical exercise has a positive effect on the formation of ... study from the Sahlgrenska Academy, University of Gothenburg, presented at ... of the Lumbar Spine (ISSLS), which is currently taking place ... shows that physical activity has a positive effect on cells ...
... revealed that the tremendous diversity of ladybird beetle species ... with impunity, poach members of ,herds, of tiny, soft-bodied ... ants that tend them.Reconstructing the evolutionary history of ladybird ... the ladybirds, first major evolutionary shift was from feeding ...
... has more than doubled in the past 10 years. ... improved cultivation technologies are essential for producers to realize ... Gaining popularity in greenhouse vegetable production is a ... a single stem. The system allows for uniform foliar ...
Cached Biology News:Exercise produces positive effects on the intervertebral discs 2Ladybirds -- wolves in sheep's clothing 2Twin-head cucumber system reduces start-up costs 2
(Date:5/29/2015)... Md. and RESEARCH TRIANGLE PARK, N.C. ... (NASDAQ: UTHR ) announced today that Roger Jeffs ... will provide an overview and update on the company,s business ... New York City . The presentation and ... June 4, 2015, at 11:00 AM Eastern Time, and can ...
(Date:5/29/2015)... Seoul Semiconductor (CEO: Chung-hoon Lee, http://www.seoulsemicon.com ), ... announced that it will increase the global automotive ... and high reliable LED product line-up for the ... developed efficient and reliable LED packages for the ... headlamps to global auto makers. Seoul Semiconductor’s 14 ...
(Date:5/28/2015)... 28, 2015 Research ... addition of Jain PharmaBiotech,s new report  "Alzheimer ...  to their offering.       (Logo: ... challenge in management. With nearly 8 million ... major markets of the world and anticipated ...
(Date:5/28/2015)... , May 28, 2015  Quest Diagnostics Incorporated (NYSE: ... information services, announced that it is scheduled to speak ... York.  Steve Rusckowski , the company,s President and ... point strategy.  The presentation is scheduled for Tuesday, June ... The presentation will be webcast live during the conference ...
Breaking Biology Technology:Seoul Semiconductor Increases the Global Automotive LED Market Share with its High Efficient and Reliable LEDs for Automotive Lightings 2Global Alzheimer Disease Report 2015-2024 - New Drugs, Markets and Companies 2Global Alzheimer Disease Report 2015-2024 - New Drugs, Markets and Companies 3Quest Diagnostics to Speak at the Jefferies 2015 Global Healthcare Conference 2
... Inspection Service approves permit for NKO(R) ... ... /PRNewswire-FirstCall/ - Neptune Technologies &,Bioressources Inc. ("Neptune") (NASDAQ.NEPT - TSX.V.NTB) is ... (TGA) in Australia that Neptune Krill Oil (NKO(R)) has,obtained approval as ...
... CLARA, Calif., Dec. 4 Finesse Solutions, LLC,Santa ... solutions for,life sciences process applications, announced the general ... designed to take the guesswork,out of validation and ... OS)., Traditional validation of control systems can ...
... of scientists,has awarded Ganeden Biotech, Inc. self-affirmed GRAS ... GanedenBC30 (Bacillus coagulans,GBI- 30, 6086). After an extensive ... concluded that GanedenBC30 is safe for use as ... self-affirmed GRAS,status is awarded to any substance that ...
Cached Biology Technology:Neptune Technologies & Bioressources Inc. obtains Complementary Medicine approval in Australia for NKO(R) 2Neptune Technologies & Bioressources Inc. obtains Complementary Medicine approval in Australia for NKO(R) 3Finesse Introduces TruBio(TM) IOQ 2Ganeden Biotech Obtains Self-Affirmed GRAS Status for Probiotic Ingredient, GanedenBC30 (Bacillus coagulans GBI-30, 6086) 2
Methylation analysis of gene promoters using bilsulfite treatment of DNA and comparative DNA sequence analysis. Probe design and PCR included....
... automated, GLP-compliant Facility , Galaxy LIMS, Sophisticated ... Highly experienced scientists ,We offer individual sample ... full plasmids for single or double strand ... when the DNA of interest is 1.3 ...
GLP-compliant, CLIA-certified DNA sequencing service. ASQ and SQA certified quality assurance staff. Auditors welcome....
Sequencing and primer design rolled into one. Just give us your clone and a reference sequence, and we'll do the rest. Single-strand or double-strand coverage. Guaranteed results....
Biology Products: