Navigation Links
A deadly scorpion provides a safe pesticide
Date:1/11/2010

Scorpions deliver a powerful, paralyzing venom ― a complex cocktail of poisonous peptides that immobilize animal prey on the spot. Some of the toxins in this cocktail damage only insects, which is why a Tel Aviv University researcher is harnessing them to create a safe and ecologically sound pesticide.

Prof. Michael Gurevitz of Tel Aviv University's Department of Plant Sciences has isolated the genetic sequences for important neurotoxins in the scorpion venom. He's also developed methods to produce and manipulate toxins to restrict their toxicity in certain insects or mammals.

"Two decades ago I realized that scorpion venom is a goldmine for possible insecticidal and therapeutic agents. This raised the question of how to use them as ecologically-safe agents against insects in a farmer's fields, or in medicinal disorders," he says.

In his study of the toxins and the evolution of their genes he recently published a paper in the journal Molecular Biology and Evolution that demonstrates how computational analyses at the gene sequence level leads to better understanding of how to manipulate toxin activity.

A venom factory in the lab

Rather than isolating the venom constituents of the Israeli yellow scorpion, known to be among the world's most poisonous scorpions, Prof. Gurevitz developed genetic methods for producing and manipulating the desired toxins in bacteria. He then investigated how they act against insects and mammals, paving the way for potential use in the agriculture industry.

He went in this direction because attempts to insert a certain neurotoxin gene into a plant genome hoping for the plant to produce the toxin and kill infesting insects has failed. As a peptide, the toxin was metabolized in the insect guts, which evidently seems to require that it first be engineered to be able to penetrate into the insect blood stream to have its impact on the nervous system.

Prof. Gurev
'/>"/>

Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University
Source:Eurekalert

Page: 1 2

Related biology news :

1. Scripps research team blocks bacterial communication system to prevent deadly staph infections
2. Northwestern to expose most deadly infectious diseases in 3-D
3. Best treatment identified to reduce deadly Staph infections
4. Research unveils new hope for deadly childhood disease
5. Deadly genetic disease prevented before birth in zebrafish
6. Ayurvedic nightshade deadly for dengue mosquito
7. Sydney harbors deadly diet for sea creatures
8. New vaccine may give long-term defense against deadly bird flu and its variant forms
9. Deadly dose: Rensselaer heparin expert helps uncover source of lethal contamination
10. Deadly rugby virus spreads in sumo wrestlers
11. 15-state Southern obesity summit to focus on deadly epidemic
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2014)... changing climate threaten some of the world,s most ... establish seed collections to save the seeds in ... some genetic diversity., For decades, these seed collections ... a one-size-fits-all approach for how many seeds to ... regardless of species, pollination mode, growth habitat and ...
(Date:7/30/2014)... from Bjorn Brembs, professor of neurogenetics at the Institute ... figure allowing readers and reviewers to run the underlying ... important leap forward for scientific publishing, by demonstrating a ... scholarly output. , Figure 3 in fact doesn,t really ... to F1000Research , and the figure is generated ...
(Date:7/30/2014)... injury (SCI), traumatic brain injury (TBI) and peripheral nerve ... learned over the past 30 years regarding both the ... growth, but this large body of information has not ... his team from University of Miami in USA proposed ... consensus is emerging that one contributing factor is a ...
Breaking Biology News(10 mins):Saving seeds the right way can save the world's plants 2F1000Research brings static research figures to life 2
... Hagfish is a strange animal: it feeds by gnawing its way ... 3 days. Scientists at the University of British Columbia (Canada) believe ... inside the carcass to become acidic from the build up of ... is able to cope with environmental conditions of up to 7% ...
... to a low-weight preemie at 24 weeks, exhibited the first-found ... and the amniotic fluid of a woman in preterm labor. ... cannot be cultured and grown in the lab, researchers from ... Department of Obstetrics and Gynecology at MetroHealth Medical Center in ...
... Dr. Peter Sarnow and a team of Stanford University scientists ... named miR-122, in order to replicate in cultured liver cells. ... amount of hepatitis C virus RNA was reduced by approximately ... potential to develop new antiviral agents against hepatitis C, the ...
Cached Biology News:Prenatal nicotine exposure reduces breathing response of newborns... 2Prenatal nicotine exposure reduces breathing response of newborns... 3
(Date:7/30/2014)... Hartford, CT (PRWEB) July 30, 2014 ... economic development organization based in East Hartford, Conn., was ... on Phase II of a project that will determine ... facility in rural north-central Connecticut. USDA Rural Development provided ... (RBEG) program for the second phase of the feasibility ...
(Date:7/30/2014)... Arlington, MA (PRWEB) July 30, 2014 ... products, announces completion of its first round of seed ... round will enable preliminary efforts to develop a novel ... the support of our investors and their commitment to ... CEO of LayerBio. "Ophthalmology is one of many areas ...
(Date:7/29/2014)... The advanced optical methods and applications for ... a revolution in the neurosciences were the inspiration behind ... SPIE, the international society for optics and photonics ... of the BRAIN Initiative in the United States, and ... vision for and provide examples of the impact that ...
(Date:7/29/2014)... foam of atom-thick sheets can be made to any ... Rice University. , In microscopic images, the foam ... and walls that reinforce each other. The structure consists ... of graphene oxide that self-assemble with the assistance of ... the foam could find use in structural components, as ...
Breaking Biology Technology:USDA Grant Funds Second Phase of Bio-Energy Research Community Economic Development in CT 2USDA Grant Funds Second Phase of Bio-Energy Research Community Economic Development in CT 3SPIE Launches 'Neurophotonics' Journal with Special Section on BRAIN Initiative 2SPIE Launches 'Neurophotonics' Journal with Special Section on BRAIN Initiative 3SPIE Launches 'Neurophotonics' Journal with Special Section on BRAIN Initiative 4Tough foam from tiny sheets 2
... 2012  Argos Therapeutics Inc., today announced that it ... AGS-003-006, a Phase 2 study of its Arcelis™ ... with advanced renal cell carcinoma (RCC). The results ... T cell responses and overall survival. AGS-003 in ...
... DIEGO, Jan. 31, 2012  bioTheranostics, Inc., a bioMerieux ... drive personalized treatment, has introduced a new product ... resistance and pathway interrogation called PRECIS Precision Medicine ... cancer management, partners accurate diagnosis of primary tumor ...
... science world, with the potential to create foldaway mobile phones, ... new finding at the University of Manchester gives graphene,s potential ... for distilling alcohol. In a report published in ... shows that graphene-based membranes are impermeable to all gases and ...
Cached Biology Technology:Argos Therapeutic Arcelis™ Immunotherapy AGS-003 in Combination With Sunitinib Shows Statistically Significant Correlation of Immune System Response to Overall Survival in Phase 2 Study in Patients with Advanced Renal Cell Carcinoma (RCC) 2Argos Therapeutic Arcelis™ Immunotherapy AGS-003 in Combination With Sunitinib Shows Statistically Significant Correlation of Immune System Response to Overall Survival in Phase 2 Study in Patients with Advanced Renal Cell Carcinoma (RCC) 3bioTheranostics Launches Precision Medicine Biomarkers for Tumor Pathway Interrogation 2bioTheranostics Launches Precision Medicine Biomarkers for Tumor Pathway Interrogation 3Supermaterial goes superpermeable 2
For the differentiation of mouse embryonic stem cells tooligodendrocytes....
Preadipocyte factor-1 [Pref-1, DLK-1], C-terminal...
IC50: 35 ng/ml · Limit of detection: 8 ng/ml...
, Glycerol 30%...
Biology Products: