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A calculator to estimate the likelihood of antidepressant response
Date:7/1/2013

d Dr. John Krystal, Editor of Biological Psychiatry. "To do better than this, we will need to include biomarkers that may serve the function that blood tests and blood pressure measurements serve in other areas of medicine."

Perlis agrees, commenting that "There has been great emphasis on the discovery of biomarkers to help predict clinical outcomes. No doubt this effort will succeed eventually. On the other hand, it's entirely possible that clinical features can help get us part of the way there - that clinical features can help make useful predictions."

"The analogy I would draw is the Framingham score for predicting cardiovascular risk. It's far from perfect, and there's plenty to criticize - but it has at least spurred efforts to use prediction in a clinical setting. It has also provided a platform to which biomarkers can be added, as they are identified," he added.

In the meantime, the whole point of providing a clinical calculator online is to allow clinicians to try it out - to see what could be done, if the will and the resources were there.


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Contact: Rhiannon Bugno
Biol.Psych@utsouthwestern.edu
214-648-0880
Elsevier
Source:Eurekalert

Page: 1 2

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