Navigation Links
A calculator to estimate the likelihood of antidepressant response
Date:7/1/2013

Philadelphia, PA-- As in any other field of medicine, when a depressed person visits a psychiatrist for treatment of depression, they like to be informed of the odds that they will respond to the medication they are prescribed. Unfortunately, there has been no precise way to predict antidepressant response in individual patients.

It would be very nice to have an equation that would enable doctors to predict the likelihood that individual patients would respond to specific treatments. Accurate predictions are likely to be challenging. The ability to accurately predict the likelihood of antidepressant response for individual patients could be an important step in developing individualized treatment plans.

The effectiveness of antidepressant medications varies tremendously across patients and the overall effectiveness of current medications is lower than previously expected. For example, the largest antidepressant trial ever conducted -- the NIMH STAR*D study -- provided somewhat discouraging news about the effectiveness of antidepressants. Only 30% of patients responded to their initial antidepressant and after one year and up to four different treatments, 30% of patients did not achieve remission.

In this issue of Biological Psychiatry, Dr. Roy Perlis at Massachusetts General Hospital has taken an important step toward this objective.

He gathered data collected from the STAR*D study and used multiple prediction models to identify statistical patterns. Using the best-performing model, he then generated an online risk calculator and visualization tool that provides a graphical estimate of an individuals' risk for treatment resistance.

"To address the needs of individual depressed patients, we will need to find ways to design psychiatric treatments to respond to the differences among patients with depression. The 'depression calculator' that emerges from the STAR*D trial is one step forward in this effort," sai
'/>"/>

Contact: Rhiannon Bugno
Biol.Psych@utsouthwestern.edu
214-648-0880
Elsevier
Source:Eurekalert

Page: 1 2

Related biology news :

1. Measuring mercury: Common test may overestimate exposure from dental amalgam fillings
2. New online tool estimates carbon and energy impact of trees
3. US underestimates costs of carbon pollution and climate change
4. Atmospheric scientists release first bottom-up estimates of Chinas CO2 emissions
5. Developing world has less than 5 percent chance of meeting UN child hunger target, study estimates
6. Ability to estimate quantity increases in first 30 years of life
7. Environmental benefit of biofuels is overestimated, new study reveals
8. Scientists provide first large-scale estimate of reef shark losses in the Pacific Ocean
9. Wind pushes plastics deeper into oceans, driving trash estimates up
10. New research lowers past estimates of sea-level rise
11. Costs for changing pollution criteria in Florida waters likely to exceed EPA estimates
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/15/2014)... University Mainz (JGU) as a full member, ensuring ... a significant nationwide standing in the field of ... Gutenberg University Mainz as a full member of ... and international competition for the best minds and ... proud that Mainz University has been recognized as ...
(Date:10/15/2014)...   Neurotechnology , a provider of high-precision ... the VeriLook Surveillance 3.0 software development kit ... face identification using live video streams from single ... version not only identifies faces in a crowd, ... they are moving through the video frame. It ...
(Date:10/14/2014)... is how to produce enough food to feed the ... Agriculture Organization of the United Nations predicts that food ... to feed a growing global population, and plants are ... production. Plants—grains, cereals, fruits, vegetables, and more—feed humans ... must tap into our knowledge of how plants work ...
Breaking Biology News(10 mins):Johannes Gutenberg University Mainz joins Germany's Gauss-Allianz as a full member 2Johannes Gutenberg University Mainz joins Germany's Gauss-Allianz as a full member 3VeriLook Surveillance 3.0 SDK Identifies Faces and Moving Objects, Differentiates Pedestrians from Other Moving Objects in Video Surveillance Systems 2VeriLook Surveillance 3.0 SDK Identifies Faces and Moving Objects, Differentiates Pedestrians from Other Moving Objects in Video Surveillance Systems 3Building a bridge from basic botany to applied agriculture 2Building a bridge from basic botany to applied agriculture 3
... Ph.D., of Fred Hutchinson Cancer Research Center, has received ... study the potential role of "genetic conflicts" in the ... colleagues want to find out whether a lost evolutionary ... whether autoimmunity when the body,s immune system turns ...
... PhD candidate has been highly awarded for his innovative image ... Norton, from the Kielpinski group in the Centre for Quantum ... following extensive work on high resolution imaging. Run ... the Extreme Imaging competition aims to promote and celebrate local ...
... French . Vancouver, B.C. -- Marine protected areas ... wrong time. As a result of changing conditions, marine species have been ... per year over the past 50 years, and forecasts of shifts of ... on where to put MPAs weren,t always made with a changing climate ...
Cached Biology News:Did an evolutionary arms race cause lupus? Biologist Harmit Malik receives grant to try and find out 2Extreme imaging wins science praise 2Marine protected areas: changing climate could require change of plans 2
(Date:10/22/2014)... October 22, 2014 Involution Studios ... release of a new infographic, Understanding Ebola . ... a beautifully designed, easy to follow informative tool for ... of outbreak, symptoms and prevention. , "As the news ... the 2014 Ebola outbreak represents not only a healthcare ...
(Date:10/22/2014)... October 22, 2014 According to ... by Service Type (Consulting, Integration, Deployment & Support), ... Deployment Model (Public, Private, Others (Hybrid & Community)) ... defines and segments the Cloud Professional Services Market ... forecasting of revenues. It also identifies the drivers ...
(Date:10/22/2014)... KONG , Oct. 22, 2014  aTyr Pharma ... that rare disease expert John C. McKew , ... McKew brings more than two decades of expertise in ... Institutes of Health, Wyeth Research and Genetics Institute, Inc. ... aTyr,s efforts to expand and translate its novel Physiocrine ...
(Date:10/20/2014)... ON , Oct. 20, 2014 /PRNewswire/ - BIOREM Inc. (TSXV: ... $1.7 million which brings Q3 orders to $5.8 million and provides ... control projects in North America and one ... continue to bid new projects at record levels," said Peter ... were higher at the end of Q3 than they have been ...
Breaking Biology Technology:Involution Studios' Ebola Infographic Provides Key Disease Information and Statistics at a Glance 2Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 2Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 3Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 4Cloud Professional Services Market by Public, Private, Hybrid & Community Expected to Reach $34.41 Billion by 2019 - New Report by MarketsandMarkets 5aTyr Pharma Appoints John C. McKew, Ph.D., as Vice President, Research 2aTyr Pharma Appoints John C. McKew, Ph.D., as Vice President, Research 3
... George Bush and Bill Clinton urge Americans to come to aid ... from two former presidents, but because of how they ask people ... and Clinton point viewers to the Web site for the ... of dollars that have streamed in over the Internet since the ...
... Hamlet: Do you see that cloud, thats almost in shape ... a camel, indeed. ,Hamlet: Methinks it is like a weasel. ... a whale? ,Polonius: Very like a whale. , Hamlet ... Shakespeare) , ,Occasionally stumbling across truth but mostly skilled ...
... Controls unveiled its newest products this week at ... The additions to the line are part of the ... ease of use for customers and branching out into ... showed off its latest vehicular battery, designed for hybrid ...
Cached Biology Technology:Outpouring of tsunami relief displays power of the Internet 2Outpouring of tsunami relief displays power of the Internet 3Follow these three rules when choosing tech consultants 2Follow these three rules when choosing tech consultants 3Follow these three rules when choosing tech consultants 4
Antibody specific for trimethyl-Lys27 of histone H3. Mouse monoclonal. Antigen: Synthetic peptide derived from histone H3, trimethylated at lysine 27...
DL-Dithiothreitol (Clelands Reagent) ,PROTEASE FREE!! ,Molecular Biology Grade ,PRODUCT MUST SHIP NEXT DAY DURING HOT SUMMER MONTHS. ,C 4 H 10 O 2 S 2 ,Molecular Weight: 154.25 ,CAS RN: [27565-...
DTT 50 l...
...
Biology Products: