Navigation Links
A built-in strategy for transgene containment

Zhejiang University, Hangzhou, China. A method of creating selective terminable transgenic rice was reported by the scientists of Zhejiang University in this weeks PLoS ONE. Unintended spreading of transgenic rice by pollen and seed dispersal is a major concern for planting transgenic rice, especially transgenic rice expressing pharmaceutical or industrial proteins.

The transgenic rice plants created in the past usually can only be detected by sophisticated molecular detection methods and it is prohibitedly difficult to identify and selectively kill the transgenic rice plants once they escape into environments and contaminate conventional rice.

However, with the technology reported by Dr. Zhicheng Shens group, the transgenic rice plants mixed in the conventional rice could be selectively eliminated by a spray of Bentazon, an herbicide commonly used for rice weed control.

This technology appears to be quite simple, reliable and inexpensive for implementation. If you use Bentazon for weed control in your rice field, you do not need to worry about any possible contamination caused by transgenic rice created by our method. The herbicide will take care of it said Dr. Shen, the corresponding author of the article. Containment of transgenic crops only by physical isolation is not sufficient in our view, as human errors, animal activities and nature accidents will lead to the spreading of transgenic rice plants sooner or later added Chaoyang Lin, graduate student in Dr. Shens laboratory and one of the leading contributors of the article. Indeed, several major accidents of unintended spreading of the transgenic crops did happen in the past several years in USA.

This technology may be best for use to contain transgenic rice as bioreactors. While all biotech products today are safe and nutritious, this technology could allow certain crops targeted for industrial, energy or health uses to be grown under controlled conditions and kept separate from other channels said Nick Duck Vice President of Research for Athenix Corp. in the USA.

The principle beneath this strategy is elegant and simple according to the article. The genes of interest in these transgenic rice plants will be linked with an RNAi cassette which suppresses the expression of the rice detoxification enzyme of Bentazon, rendering the transgenic rice to be sensitive to the herbicide. Conventional rice is highly tolerant to Bentazon.

Dr. Shens lab is currently using the technology for developing transgenic rice as well as corn for expression of industrial enzymes and pharmaceutical proteins. We believe that transgenic crops are the future, and we feel much better knowing that we may release selectively terminable transgenic plants in the future to address the concern of transgene spreading, said Dr. Shen.


Contact: Dr. Zhicheng Shen
Public Library of Science

Related biology news :

1. Built-in exercise monitor predicts fitness
2. A screening strategy using zebrafish targets genes that protect against hearing loss
3. ETH Zurich competence center ESC introduces energy strategy
4. Strategy for nanotechnology-related environmental, health and safety research
5. Carbon capture strategy could lead to emission-free cars
6. Texas Hospital nations first to use large-scale cocoon strategy against whooping cough
7. New screening strategy for detection of chagas disease in children
8. Lupus Research Institute strategy delivers $30 million in national funding
9. Bee strategy helps servers run more sweetly
10. Penn Veterinary Medicine report new strategy to create genetically-modified animals
11. Embryonic stem cell strategy advanced with UCSF finding
Post Your Comments:
(Date:10/29/2015)... , Oct. 29, 2015  Rubicon Genomics, Inc., ... U.S. distribution of its DNA library preparation products, ... Rubicon,s new ThruPLEX Plasma-seq kit. ThruPLEX Plasma-seq has ... preparation of NGS libraries for liquid biopsies--the analysis ... and prognostic applications in cancer and other conditions. ...
(Date:10/27/2015)... Oct. 27, 2015 In the present market ... concern for various industry verticals such as banking, healthcare, ... the growing demand for secure & simplified access control ... such as hacking of bank accounts, misuse of users, ... such as PC,s, laptops, and smartphones are expected to ...
(Date:10/26/2015)... Calif. and LAS VEGAS ... Nok Nok Labs , an innovator in modern authentication ... , today announced the launch of its latest version ... unified platform enabling organizations to use standards-based authentication that ... Nok Nok S3 Authentication Suite is ideal for organizations ...
Breaking Biology News(10 mins):
(Date:11/25/2015)... 2015 Studies reveal the differences ... and pave the way for more effective treatment for one ...   --> --> ... problems in cats, yet relatively little was understood about the ... have been conducted by researchers from the WALTHAM Centre for ...
(Date:11/25/2015)... 2015 /PRNewswire/ - Aeterna Zentaris Inc. (NASDAQ:  AEZS; TSX: ... prospects remain fundamentally strong and highlights the following ... received DSMB recommendation to continue the ZoptEC Phase ... the final interim efficacy and safety data ... men with heavily pretreated castration- and Taxane-resistant prostate ...
(Date:11/25/2015)... Oregon , November 25, 2015 ... Market Research Report is a professional and in-depth ... industry.      (Logo: ) ... overview of the industry including definitions, classifications, applications ... is provided for the international markets including development ...
(Date:11/24/2015)... HILLS, N.J. (PRWEB) , ... November 24, 2015 , ... ... as the recipient of the 2016 USGA Green Section Award. Presented annually since 1961, ... golf through his or her work with turfgrass. , Clarke, of Iselin, ...
Breaking Biology Technology: