Navigation Links
A built-in strategy for transgene containment
Date:3/18/2008

Zhejiang University, Hangzhou, China. A method of creating selective terminable transgenic rice was reported by the scientists of Zhejiang University in this weeks PLoS ONE. Unintended spreading of transgenic rice by pollen and seed dispersal is a major concern for planting transgenic rice, especially transgenic rice expressing pharmaceutical or industrial proteins.

The transgenic rice plants created in the past usually can only be detected by sophisticated molecular detection methods and it is prohibitedly difficult to identify and selectively kill the transgenic rice plants once they escape into environments and contaminate conventional rice.

However, with the technology reported by Dr. Zhicheng Shens group, the transgenic rice plants mixed in the conventional rice could be selectively eliminated by a spray of Bentazon, an herbicide commonly used for rice weed control.

This technology appears to be quite simple, reliable and inexpensive for implementation. If you use Bentazon for weed control in your rice field, you do not need to worry about any possible contamination caused by transgenic rice created by our method. The herbicide will take care of it said Dr. Shen, the corresponding author of the article. Containment of transgenic crops only by physical isolation is not sufficient in our view, as human errors, animal activities and nature accidents will lead to the spreading of transgenic rice plants sooner or later added Chaoyang Lin, graduate student in Dr. Shens laboratory and one of the leading contributors of the article. Indeed, several major accidents of unintended spreading of the transgenic crops did happen in the past several years in USA.

This technology may be best for use to contain transgenic rice as bioreactors. While all biotech products today are safe and nutritious, this technology could allow certain crops targeted for industrial, energy or health uses to be grown under controlled conditions and kept separate from other channels said Nick Duck Vice President of Research for Athenix Corp. in the USA.

The principle beneath this strategy is elegant and simple according to the article. The genes of interest in these transgenic rice plants will be linked with an RNAi cassette which suppresses the expression of the rice detoxification enzyme of Bentazon, rendering the transgenic rice to be sensitive to the herbicide. Conventional rice is highly tolerant to Bentazon.

Dr. Shens lab is currently using the technology for developing transgenic rice as well as corn for expression of industrial enzymes and pharmaceutical proteins. We believe that transgenic crops are the future, and we feel much better knowing that we may release selectively terminable transgenic plants in the future to address the concern of transgene spreading, said Dr. Shen.


'/>"/>

Contact: Dr. Zhicheng Shen
zcshen@zju.edu.cn
Public Library of Science
Source:Eurekalert

Related biology news :

1. Built-in exercise monitor predicts fitness
2. A screening strategy using zebrafish targets genes that protect against hearing loss
3. ETH Zurich competence center ESC introduces energy strategy
4. Strategy for nanotechnology-related environmental, health and safety research
5. Carbon capture strategy could lead to emission-free cars
6. Texas Hospital nations first to use large-scale cocoon strategy against whooping cough
7. New screening strategy for detection of chagas disease in children
8. Lupus Research Institute strategy delivers $30 million in national funding
9. Bee strategy helps servers run more sweetly
10. Penn Veterinary Medicine report new strategy to create genetically-modified animals
11. Embryonic stem cell strategy advanced with UCSF finding
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/2/2016)...   The Weather Company , an IBM Business (NYSE: ... capability in which consumers will be able to interact with ... via voice or text and receive relevant information about the ... Marketers have long sought an advertising solution that can create ... relevant and valuable; and can scale across millions of interactions ...
(Date:5/20/2016)... , May 20, 2016  VoiceIt is excited ... with VoicePass. By working together, VoiceIt ...  Because VoiceIt and VoicePass take slightly different approaches ... increases both security and usability. ... about this new partnership. "This marketing ...
(Date:5/3/2016)... , May 3, 2016  Neurotechnology, a provider ... MegaMatcher Automated Biometric Identification System (ABIS) , ... multi-biometric projects. MegaMatcher ABIS can process multiple complex ... any combination of fingerprint, face or iris biometrics. ... SDK and MegaMatcher Accelerator , which ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... , June 27, 2016  Global demand ... 4.6 percent through 2020 to $7.2 billion.  This ... and beverages, cleaning products, biofuel production, animal feed, ... biotechnology, diagnostics, and biocatalysts). Food and beverages will ... driven by increasing consumption of products containing enzymes ...
(Date:6/27/2016)... ... June 27, 2016 , ... ... on what they believe could be a new and helpful biomarker for malignant ... Click here to read it now. , Biomarkers are components in ...
(Date:6/27/2016)... ... 27, 2016 , ... Rolf K. Hoffmann, former senior vice ... University of North Carolina Kenan-Flagler Business School effective June 27. , ... with a focus on the school’s international efforts, leading classes and participating in ...
(Date:6/24/2016)... -- Regular discussions on a range of subjects including policies, debt ... said Poloz. Speaking at a lecture to the ... pointed to the country,s inflation target, which is set by ... "In certain areas there needs to ... goals, why not sit down and address strategy together?" ...
Breaking Biology Technology: