Navigation Links
A brain filter for clear information transmission
Date:9/6/2012

This press release is available in German.

Stefan Remy and colleagues at the German Center for Neurodegenerative Diseases (DZNE) and the University of Bonn have illuminated how this system works. "The system acts like a filter, only letting the most important impulses pass," explains Remy. "This produces the targeted neuronal patterns that are indispensible for long-term memory storage."

How does this refined control system work? How can inhibitory signals produce precise output signals? This was the question investigated by Remy and his colleagues. Scientists have known for some time that this inhibitory system is crucial for the learning process. For instance, newest research has shown that this system breaks down in Alzheimer's patients. Remy and his team investigated the nerve cells of the hippocampus, a region of the brain that plays a crucial role in memory formation.

The information we learn or remember is processed in the brain through nerve impulses. Incoming signals enter the cell as excitatory signals. Here, they are processed via branched structures, known as dendrites, and are sent selectively to neighboring neurons. The dendrites in this brain region serve as efficient amplifiers for synchronous signals.

"We were able to show that in specific dendrites, the 'strong' dendrites, clustered signals are amplified very well. 'Weak' dendrites only transmit signals in certain phases," says Christina Mller, postdoctoral student in Remy's working group and the lead author of the study to appear in Neuron. Dendrites are excitable to differing degrees. 'Strong' dendrites transmit synchronous excitatory signals precisely and very reliably. They can resist any inhibition. Thus ensures specific signals, perhaps most relevant for learning and memory, are reliably transmitted. This results in defined patterns of activity that are
'/>"/>

Contact: Sonja Jlich-Abbas
sonja.juelich-abbas@dzne.de
49-228-433-02263
Helmholtz Association of German Research Centres
Source:Eurekalert

Page: 1 2

Related biology news :

1. REST is crucial for the timing of brain development
2. Holding a mirror to brain changes in autism
3. Strong scientific evidence that eating berries benefits the brain
4. The Japanese traditional therapy, honokiol, blocks key protein in inflammatory brain damage
5. Step forward in research into new treatments for brain edema
6. University of Alberta led research may have discovered how memories are encoded in our brains
7. Nanotherapy: Treating deadly brain tumors by delivering big radiation with tiny tools
8. Friendly to a fault, yet tense: Personality traits traced in brain
9. New discoveries about brain-hand connection sought to improve therapies, treatments, prosthetics
10. Autism risk gene linked to differences in brain structure
11. Amyloid beta in the brain of individuals with Alzheimers disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/7/2015)... , June 30, 2015 ... has announced the addition of the "Capacitive ... offering. To this date, fingerprint sensing ... technology and fingerprint sensors are well developed. This ... sensing technology. The domain of capacitive ...
(Date:7/2/2015)... Research and Markets( http://www.researchandmarkets.com/research/jvft55/next_generation ) has ... Market by Application, Technology, Function & Geography - Global ... The next generation biometrics market is expected to ... 17.9% between 2015 and 2020 Travel & ... Safran SA ( France ), NEC ...
(Date:6/29/2015)... 2015 Research and Markets( ... "Latin America Biomedical Sensors Market - Growth, Trends & ... The Latin America Biomedical Sensors market is estimated at ... over the period 2014-2020 The near future ... genetic formulation of each individual. These sensors can be ...
Breaking Biology News(10 mins):Worldwide Capacitive Fingerprint Sensors Patent Landscape Market Report 2015-2020 - Main IP Holders include Seiko Epson, AuthenTec, Sony and STMicroelectronics 2Next Generation Biometrics Market 2015 - Global Forecast to 2020 with Safran, NEC, 3M Cogent, Fujitsu & Suprema Dominating the $24 Billion Market 2Next Generation Biometrics Market 2015 - Global Forecast to 2020 with Safran, NEC, 3M Cogent, Fujitsu & Suprema Dominating the $24 Billion Market 3Latin America Biomedical Sensors Market Report 2015-2020 2
... of a commonly used atypical antipsychotic drug improved survival ... Chicago researchers report this month. The result offers promise ... currently lacks approved drugs for treatment. Mice treated ... likely to maintain their weight when given an exercise ...
... "improved cookstoves" (ICs) and traditional mud stoves has found ... the worrisome "black carbon," or soot, particles that are ... mud stoves or open-cook fires. The report, which raises ... technology in the developing world, appears in ACS, journal ...
... impact of climate change on Chinese cereal crops has found ... published in the Journal of the Science of Food ... warming increases in temperature from 1980 onwards correlated with both ... The study was carried by Dr. Tianyi Zhang, from the ...
Cached Biology News:Antipsychotic drug may be helpful treatment for anorexia nervosa 2Antipsychotic drug may be helpful treatment for anorexia nervosa 3Is rainfall a greater threat to China's agriculture than warming? 2
(Date:7/29/2015)... July 30, 2015 Sanofi, ... publie ses résultats pour le premier semestre 2015. ... les résultats. Visionner l,interview vidéo et ... Au sommaire de l,interview :  ... Moteurs de croissance - Diabète ...
(Date:7/29/2015)... , July 29, 2015 US-Australian drug ... ) today confirmed it is committed to progressing its ... soon as practicable and to ensure the Company delivers ... Executive Officer, Iain Ross , said the Company ... the lead pre-clinical programs, discovery programs and academic partnerships ...
(Date:7/29/2015)... MONTREAL , July 29, 2015 /PRNewswire/ - BioAmber Inc. ... Laurin , the Company,s Chief Financial Officer has resigned.  ... former Chief Financial Officer who retired in December 2014, ... search for a permanent successor.     Andy ... Mr. Laurin and ensure a smooth transition.  Andy was ...
(Date:7/29/2015)...  AsureQuality and Ubiquitome have agreed to collaborate ... food and primary production sectors. The collaboration will ... the Freedom4. AsureQuality provides quality assurance ... shelf for producers, processors and Competent Authorities around ... control and pest management and surveillance programmes. ...
Breaking Biology Technology:Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 2Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 3Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 4Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 5Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 6Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 7Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 8Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 9Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 10BioAmber Announces Change in Chief Financial Officer 2BioAmber Announces Change in Chief Financial Officer 3AsureQuality and Ubiquitome Partner on Applications for Mobile Molecular Food Safety Testing 2
... NutraCea (OTC Bulletin Board:,NTRZ), a world leader in ... today that it has appointed Olga Hernandez-Longan [45],to ... in accordance with,his previously announced intentions, has retired ... and advisory capacity., Ms. Hernandez-Longan has over ...
... net loss narrows on higher revenue due to Roche milestone ... ITMN ) today announced results from operations for the third,quarter ... net,loss for the third quarter of 2008 of $12.5 million, ... million, or $0.66 per share, in the third,quarter of 2007., ...
... Pa., Nov. 6 ViroPharma Incorporated,(Nasdaq: VPHM ... chief,executive officer of ViroPharma, will present at the ... P.M. ET on Wednesday, November,12, 2008. The conference ... Hotel., ViroPharma also announced that Colin Broom, ...
Cached Biology Technology:NutraCea Appoints New Chief Financial Officer 2InterMune Reports Third Quarter 2008 Financial Results and Business Highlights 2InterMune Reports Third Quarter 2008 Financial Results and Business Highlights 3InterMune Reports Third Quarter 2008 Financial Results and Business Highlights 4InterMune Reports Third Quarter 2008 Financial Results and Business Highlights 5InterMune Reports Third Quarter 2008 Financial Results and Business Highlights 6InterMune Reports Third Quarter 2008 Financial Results and Business Highlights 7InterMune Reports Third Quarter 2008 Financial Results and Business Highlights 8InterMune Reports Third Quarter 2008 Financial Results and Business Highlights 9ViroPharma to Present at Three November Healthcare Conferences 2
Human Norrin Biotinylated Affinity Purified PAb Protein Family: Other Growth Factors, Other Wnt-related Molecules...
Human VASA Biotinylated Affinity Purified PAb...
Immunogen: Synthetic Peptide: C N(185) D G T E F G G S I Y Q K(197) Storage: -20 C, Avoid Freeze/Thaw Cycles...
interferon-related developmental regulator 2...
Biology Products: