Navigation Links
A CNIO team reduces the size of the human genome to 19,000 genes
Date:7/3/2014

How nutrients are metabolised and how neurons communicate in the brain are just some of the messages coded by the 3 billion letters that make up the human genome. The detection and characterisation of the genes present in this mass of information is a complex task that has been a source of ongoing debate since the first systematic attempts by the Human Genome Project more than ten years ago.

A study led by Alfonso Valencia, Vice-Director of Basic Research at the Spanish National Cancer Research Centre (CNIO) and head of the Structural Computational Biology Group, and Michael Tress, researcher at the Group, updates the number of human genes those that can generate proteins to 19,000; 1,700 fewer than the genes in the most recent annotation, and well below the initial estimations of 100,000 genes. The work, published in the journal Human Molecular Genetics, concludes that almost all of these genes have ancestors prior to the appearance of primates 50 million years ago.

"The shrinking human genome," that's how Valencia describes the continuous corrections to the numbers of the protein-coding genes in the human genome over the years that has culminated in the approximately 19,000 human genes described in the present work. "The coding part of the genome [which produces proteins] is constantly moving," he adds: "No one could have imagined a few years ago that such a small number of genes could make something so complex."

The scientists began by analysing proteomics experiments; proteomics is the most powerful tool to detect protein molecules. In order to determine a map of human proteins the researchers integrated data from seven large-scale mass spectrometry studies, from more than 50 human tissues, "in order to verify which genes really do produce proteins " says Valencia.

FEWER THAN TEN NEW GENES SEPARATE MICE AND MEN

The results brought to light just over 12,000 proteins and the res
'/>"/>

Contact: Nuria Noriega
nnoriega@cnio.es
Centro Nacional de Investigaciones Oncologicas (CNIO)
Source:Eurekalert  

Page: 1 2 3

Related biology news :

1. Soy-based S-equol supplement reduces metabolic syndrome risk factors
2. Minimally invasive treatment for ruptured aneurysm: Safe, reduces mortality
3. Laparoscopy reduces the risk of small-bowel obstruction
4. Hot sauce ingredient reduces beer belly fat as a weight-loss surgery alternative
5. The absence of elephants and rhinoceroses reduces biodiversity in tropical forests
6. Drugs from lizard saliva reduces the cravings for food
7. New study: Snacking on raisins significantly reduces overall post-meal blood sugar levels
8. Cystic fibrosis makes airways more acidic, reduces bacterial killing
9. Study in mice discovers injection of heat-generating cells reduces belly fat
10. Eating well during pregnancy reduces babys obesity risk regardless of moms size
11. RTS,S malaria candidate vaccine reduces malaria by approximately one-third in African infants
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
A CNIO team reduces the size of the human genome to 19,000 genes
(Date:4/13/2015)... 13, 2015 According to ... Biometrics Market Forecast & Opportunities, 2020", the global biometrics ... around 14% till 2020. The biometrics market is ... implementation and review of biometric management systems. The ... products with greater efficiency, are resulting in increasing ...
(Date:4/8/2015)... , April 8, 2015  Infinisource, a leading ... services, and Morpho, a leading supplier of biometric ... produce the market,s most advanced biometrically-enabled time clock, ... NXG time clock is setting a bold, new ... data for the small and mid-size employer. When ...
(Date:4/2/2015)... , April 2, 2015 According ... 2015 attributed to somewhat higher than 125 MSEK. This ... year-end report 2014 that revenues for Q1 2015 would ... company reported for Q4 2014. The operating result for ... negative. The complete interim report will as previously communicated ...
Breaking Biology News(10 mins):Global Biometrics Market to Cross US$ 21 Billion by 2020: TechSci Research 2iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 2iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 3Fingerprint Cards Revises Revenues for Q1 2015 2
... MD -- The Biophysical Society is pleased to announce the ... Now in its third year and supported by supported by ... young investigators at the interface of the physical and life ... 2012 in San Diego, California as part of the Biophysical ...
... mean sinking your toes into smooth sand or walking firm-footed on ... exactly what it is that makes granular materials change from a ... a beach or rice grains in a hopper, being able to ... of a wide range of products. In a study ...
... MISSISSIPPI STATE, MISSISSIPPIAuthors of a recent study examined ... exactly how much plant knowledge is required for professionals ... Stortz evaluated the attitudes and perceptions of practicing landscape ... the importance of horticultural knowledge. The survey results were ...
Cached Biology News:Researchers explain what makes granular material become solid 2Researchers explain what makes granular material become solid 3Landscape architecture survey: Is plant knowledge passé? 2
(Date:5/4/2015)... 4, 2015  Tikcro Technologies Ltd. (OTCQB: TIKRF) announced ... Form 20-F for the fiscal year ended December 31, ... The annual report on Form 20-F contains information regarding ... the area of cancer immune checkpoints. This project aims ... specificity and binding in targeting certain identified immune checkpoints. ...
(Date:5/4/2015)... Genedata, a leading provider of ... science research, today announced the release of ... its enterprise solution for biologics R&D. This first-in-class ... discovery and development of novel biotherapeutics. Version 5.0 ... protein optimization and developability requirements. Genedata will present ...
(Date:5/4/2015)... --  Tocagen Inc. , a clinical-stage immuno-oncology company, ... investigational studies were presented at the 11 th ... Neurological Surgeons (AANS)/Congress of Neurological Surgeons (CNS) Section ... Washington, D.C. In addition, Tocagen ... and continues to advance towards initiation of a ...
(Date:5/1/2015)... 2015 OncoTAb, Inc., a ... company, announced that Pinku Mukherjee, Ph.D. has received the ... of Governors’ highest faculty honor. Mukherjee received the award, ... for her innovative research and development of cancer diagnostics ... a crowning moment in my scientific career,” said Mukherjee, ...
Breaking Biology Technology:Tikcro Technologies Files Annual Report on Form 20-F for the Year Ended December 31, 2014 2Genedata Biologics 5.0 – Antibody Engineering and Developability Assessment Advances 2Genedata Biologics 5.0 – Antibody Engineering and Developability Assessment Advances 3Genedata Biologics 5.0 – Antibody Engineering and Developability Assessment Advances 4Tocagen Presents Updated Interim Survival Data from Ongoing Clinical Studies at American Association of Neurological Surgeons (AANS)/Congress of Neurological Surgeons (CNS) Section on Tumors 2Tocagen Presents Updated Interim Survival Data from Ongoing Clinical Studies at American Association of Neurological Surgeons (AANS)/Congress of Neurological Surgeons (CNS) Section on Tumors 3Tocagen Presents Updated Interim Survival Data from Ongoing Clinical Studies at American Association of Neurological Surgeons (AANS)/Congress of Neurological Surgeons (CNS) Section on Tumors 4Tocagen Presents Updated Interim Survival Data from Ongoing Clinical Studies at American Association of Neurological Surgeons (AANS)/Congress of Neurological Surgeons (CNS) Section on Tumors 5OncoTAb CSO Awarded the University of North Carolina’s O. Max Gardner Award 2
... Forest Laboratories, Inc.,(NYSE: FRX ), an ... its Fiscal 2009 Second Quarter financial results,before the ... 2008. Later that,day, at 10:00 AM EDT, Forest ... President and Chief Operating Officer and Frank Perier, ...
... (OTC,Bulletin Board: SCIE), a San Diego-based medical device ... WavSTAT(R) Optical Biopsy,System to the University of Southern ... Biopsy System as an adjunctive tool to improve,clinical ... esophagus.,This marks the final phase of a study ...
... October 1 Excalibur, the international,investment house specialising ... be achieved in the UK biotech sector,despite the ... Professor Sir Christopher Evans and a development,of Merlin ... York Pharma plc, the specialist dermatology company, to ...
Cached Biology Technology:Forest Laboratories, Inc. Sets Date and Conference Call for Fiscal 2009 Second Quarter Earnings 2University of Southern California Receives Cancer Diagnosis System for Detecting Esophageal Dysplasia 2University of Southern California Receives Cancer Diagnosis System for Detecting Esophageal Dysplasia 3University of Southern California Receives Cancer Diagnosis System for Detecting Esophageal Dysplasia 4Excalibur - 'Transforming' Biotech Deals can Still be Achieved 2
Request Info...
Request Info...
CoverWell imaging chamber gasket with adhesive, one chamber, 20 mm diameter, 1.0 mm deep *set of 40* Cell Biology Imaging Tools and Accessories Microscope Slide Accessories...
Request Info...
Biology Products: