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8 hours of resistance
Date:5/25/2011

Prof. Yosef Yarden of the Biological Regulation Department, Prof. Eytan Domany of the Physics of Complex Systems Department and Prof. Moshe Oren of the Molecular Cell Biology Department. The study was coordinated by former graduate student Dr. Yaara Zwang; taking part were Aldema Sas-Chen, Yotam Drier, Dr. Tal Shay, Roi Avraham, Dr. Mattia Lauriola, Efrat Shema and Efrat Lidor-Nili. Also taking part were clinical researchers: Dr. Jasmine Jacob-Hirsch, Dr. Ninette Amariglio and Prof. Gideon Rechavi of the Chaim Sheba Medical Center and Drs. Yiilng Lu and Gordon B. Mills of the M.D. Anderson Cancer Center at the University of Texas.

This research sheds new light on the differences between healthy and cancerous cells. It might help develop new effective approaches to chemotherapy. Cancerous tumors sometimes develop resistance to the therapy, among other reasons because it stresses the body. The stress, in turn, leads to the production of growth factors that cause cells to divide, so that the treatment ultimately defeats itself. A better understanding of how growth factors work can help identify intervals for chemotherapy that will prevent the increased division of cancerous cells.


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Contact: Yivsam Azgad
news@weizmann.ac.il
972-893-43856
Weizmann Institute of Science
Source:Eurekalert

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