8 National Medals of Science awardees to be honored at gala, then the W...(which steroid hormones act in target cel...)

Date:9/29/2008

which steroid hormones act in target cells. They showed that steroid hormones regulate de novo synthesis of specific proteins by regulating the levels of specific mRNAs in target cells. Using cell-free transcription methods, they substantiated "initiation of transcription" as the rate-limited step at which nuclear receptors regulate gene expression and defined steroid hormone receptors as transcription factors.

Prior to serving at Baylor College, O'Malley spent four years at the Vanderbilt University as the Luscious Birch Professor and Director of the Reproductive Biology Center, and another four years at the National Institutes of Health as Molecular Biology section head at the Eunice Kennedy Shriver National Institute of Child Health and Human Development.

O'Malley graduated from the University of Pittsburgh School of Medicine and did his clinical residency at Duke University Medical Center.

Charles P. Slichter - University of Illinois at Urbana-Champaign

For establishing nuclear magnetic resonance as a powerful tool to reveal the fundamental molecular properties of liquids and solids. His inspired teaching has led generations of physicists and chemists to develop a host of modern technologies in condensed matter physics, chemistry, biology, and medicine.

Professor Charles Slichter, internationally recognized in condensed matter physics, is one of the world's top research scientists in the area of magnetic resonance, as well as a leading innovator in applications of resonance techniques to understanding the structure of matter. Slichter's deep physical insight and elegant experimental mastery have allowed him to make seminal contributions to an extraordinarily broad range of problems of great theoretical interest and technological importance in physics and chemistry.

While now retired from teaching, Slichter maintains an active research program and remains a vital presence in the physics department.
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Contact: Lisa-Joy Zgorski lisajoy@nsf.gov 703-292-8311 National Science Foundation Source:Eurekalert

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