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7 CAMH scientists win Young Investigator awards focused on breakthrough research
Date:1/11/2011

y environment. Not only will this approach measure motivational deficits and affected brain regions more objectively than past methods, but the results are also expected to help guide the development of future treatments for these deficits in schizophrenia.

Dr. Zachary Kaminsky will conduct research on major depression in identical twins in a study involving epigenetics. This field of research examines how developmentally acquired or environmentally triggered changes to chemical attachments on DNA can alter the ability of genes to produce proteins. He will search for epigenetic markers in the blood, which will provide the basis for early diagnostic and therapeutic developments for depression.

Dr. Romina Mizrahi will use a brain imaging technique developed at CAMH to "see" brain inflammation levels in people with schizophrenia. This will be useful to test new treatment strategies and understand how inflammation relates to the severity of schizophrenia.

Dr. Tarek Rajji will study the effects of a brain stimulation technique to enhance brain plasticity, and consequently address attention and memory problems, in people with schizophrenia. Deficits with these complex thinking processes are common features of the illness, and improvements could enhance individuals' ability to function in society as well as their overall quality of life.

Dr. Arun Tiwari's research will examine the role that genes play on side effects that some people with schizophrenia experience after taking antipsychotic medicines. Understanding the genetic causes of the side effects that lead to obesity, diabetes, high blood pressure and other related symptoms will help predict who is at risk and which medications to take.

Dr. Aristotle Voineskos will conduct research on a brain stimulation treatment among people with schizophrenia to improve "working memory" deficits, which can lead to improvements in real-world function. In addition, he will examine wh
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Contact: Michael Torres
media@camh.net
416-595-6015
Centre for Addiction and Mental Health
Source:Eurekalert

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