Navigation Links
454 Sequencing uncovers a genetic basis for different social behaviors in wasp
Date:9/27/2007

Branford, September 27, 2007

454 Life Sciences, a Roche company, in collaboration with researchers from the University of Illinois at Urbana-Champaign today announced that they have uncovered genetic underpinnings to social behavior in wasps. Using the companys Genome Sequencer system, the researchers examined messenger RNA from the brains of wasps and correlated different expression patterns to different social behaviors. The study, entitled "Wasp brain gene expression supports an evolutionary link between maternal behavior and eusociality," appears online (ahead of print) today in the journal Science.

The presence of workers that forgo reproduction and care for their siblings is a defining feature of eusociality and a major challenge for evolutionary theory. It has been proposed that worker behavior evolved from maternal care behavior. The researchers explored this idea by studying gene expression (what genes are active and to what extent) in wasps. Gene expression in workers was more similar to foundresses, which show maternal care, than to queens and gynes, which do not. Insulin-related genes were among those genes showing a distinct pattern, suggesting that the evolution of eusociality involves major nutritional and reproductive pathways.

Our goal was to test the prediction that maternal and worker (eusocial) behaviors share a common molecular basis explained Gene Robinson, PhD., senior author and G. William Arends Professor of Integrative Biology and Director of the Neuroscience Program at the University of Illinois. We used 454 Sequencing, together with the recently sequenced honey bee genome, to rapidly bring genomics to a model social organism, the wasp. This research is an early example of the utility of 454 sequencing for transcriptomics.

The Genome Sequencer generates hundreds of thousands of long, highly-accurate reads in a single run, giving researchers unprecedented detail and accuracy for transcriptome profiling and gene expression applications, explained Michael Egholm, Ph.D., Vice President of Research and Development at 454 Life Sciences. These and other applications enabled by 454 Sequencing are opening the door on social genomics. We are going to learn about how social behavior is coded in the genome and how it has evolved, which could have a lot of relevance to understanding human behavior."

454 Life Sciences develops and commercializes the innovative Genome Sequencer system for ultra-high-throughput DNA sequencing. Specific applications include de novo sequencing and re-sequencing of whole genomes, metagenomics, RNA analysis, and targeted sequencing of DNA regions of interest. The hallmarks of 454 Sequencing are its simple, unbiased sample preparation and long, highly accurate sequence reads, including paired reads. 454 Sequencing technology has enabled many peer-reviewed studies in diverse research fields such as: cancer research, infectious diseases research, drug discovery, marine biology, anthropology, paleontology, and many more.


'/>"/>

Contact: Benjamin Carmichael
benjamin.carmichael@russopartnersllc.com
212-845-4242
Noonan/Russo Communications
Source:Eurekalert

Related biology news :

1. Color-blind method opens new doors in DNA sequencing
2. Gene sequencing explains bioremediation bug
3. Sequencing of marine bacterium will help study of cell communication
4. NHGRI targets 12 more organisms for genome sequencing
5. NHGRI Selects 13 More Organisms for Genome Sequencing
6. NHGRI expands effort to revolutionize sequencing technologies
7. Sequencing our seas
8. Detection of DNA on nanotubes offers new sensing, sequencing technologies
9. Genome sequencing is for ecologists, too
10. NHGRI announces new sequencing targets
11. Nanopore method could revolutionize genome sequencing
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/20/2016)... 20, 2016  Synaptics Incorporated (NASDAQ: SYNA ... today announced sampling of S1423, its newest ClearPad ... small screen applications including smartwatches, fitness trackers, and ... and rectangular shapes, as well as thick and ... moisture on screen, while wearing gloves, and supports ...
(Date:1/15/2016)... , Jan. 15, 2016 Recent publicized ... small to find new ways to ensure data security ... iOS and Android that ties ... biometrics, transforming it into a hardware authorization token. Customer ... swipe their fingerprint on their KodeKey enabled device to ...
(Date:1/13/2016)... , January 13, 2016 /PRNewswire/ ... announced the addition of the  "India ... Estimation & Forecast (2015-2020)"  report ... http://www.researchandmarkets.com/research/7h6hnn/india_biometrics ) has announced the addition ... Identification Market - Estimation & Forecast ...
Breaking Biology News(10 mins):
(Date:2/8/2016)... , February 8, 2016 ... Genetics" or the "Company"), the ultra-rapid Point-Of-Care (POC) molecular diagnostics ... Mark its Chlamydia trachomatis (CT) test to be launched on ... IVD Directive (98/79/EC), the CT test is now cleared for ... --> The launch of the io® CT test ...
(Date:2/6/2016)... Virginia (PRWEB) , ... February 06, 2016 , ... ... E-mail: amitchell(at)cee(dot)org , The Center for Excellence in Education Sponsors Teacher Training ... VA – February 4, 2016 – The Center for Excellence in Education (CEE) ...
(Date:2/5/2016)... CHAPEL HILL, N.C. , Feb. 5, 2016 /PRNewswire/ ... a key role for a host of launch activities ... The importance of this launch activity is especially high ... are specialists. Best Practices and the Role ... study will help companies focused on oncology therapies find ...
(Date:2/5/2016)... -- Amarantus BioScience Holdings, Inc. ... products for Regenerative Medicine, Neurology and Orphan Diseases, announced ... from the US Food and Drug Administration (FDA) for ... granted orphan drug designation (ODD) by the US FDA ... Inc. (OTCQB: AMBS), a biotechnology company ...
Breaking Biology Technology: