Navigation Links
4 days of REM sleep deprivation contributes to a reduction of cell proliferation in rats
Date:2/1/2008

WESTCHESTER, Ill. Four days exposure to a REM sleep deprivation procedure reduces cell proliferation in the part of the forebrain that contributes to long-term memory of rats, according to a study published in the February 1 issue of the journal SLEEP.

The study, authored by Dennis McGinty, PhD, of the V.A. Greater Los Angeles Healthcare System, focused on male Sprague-Dawley rats. REM sleep deprivation was achieved by a brief treadmill movement initiated by automatic online detection of REM sleep. A yoked-control (YC) rat was placed in the same treadmill and experienced the identical movement regardless of the stage of the sleep-wake cycle.

According to the results, REM sleep was reduced by 85 percent in REM sleep deprived rats and by 43 percent in YC rats. Cell proliferation was reduced by 63 percent in REM sleep deprived rats compared with YC rats. Across all animals, cell proliferation exhibited a positive correlation with the percentage of REM sleep.

Several studies have shown that sleep contributes to brain plasticity in general, and to adult neurogenesis, in particular, said Dr. McGinty. Neurogenesis is a concrete example of brain plasticity, suppression of adult neurogenesis is thought to be important in pathologies such as depression. One current question has to do with the relative contribution of the two sleep states, non-REM and REM, which have very different, even opposite, physiological properties. This study showed that REM sleep has a critical role in facilitating brain plasticity. The study does not exclude an equally important role for non-REM sleep. In other recent work, we have shown that sleep fragmentation can also suppress adult neurogenesis. How sleep affects the molecular mechanisms underlying neurogenesis remains to be explored.

It is recommended that older adults get between seven and eight hours of nightly sleep.

The American Academy of Sleep Medicine (AASM) offers the following
'/>"/>

Contact: Jim Arcuri
jarcuri@aasmnet.org
708-492-0930
American Academy of Sleep Medicine
Source:Eurekalert

Page: 1 2

Related biology news :

1. Alcohol and sleep restriction can affect young mens alertness and driving performance
2. Ohio scientists develop blue-blocking glasses to improve sleep and ADHD symptoms
3. Journal Sleep: Insomniacs are more likely to report a family history of the sleep disorder
4. Snoozing worms help Penn researchers explain the evolution of sleep
5. KGI professor contributes new insights on jumping genes
6. Mayo Clinic study: Ossurs collars superior in immobilization and reduction of pressure
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/29/2014)... study from UC San Francisco is the first to ... overtime and accelerate cellular aging, these negative effects may ... sleeping well. , "The study participants who exercised, ... than the ones who didn,t maintain healthy lifestyles, even ... author Eli Puterman, PhD, assistant professor in the department ...
(Date:7/28/2014)... University of Arizona has sequenced the complete genome of ... and agriculturalists, understanding of the growing patterns of African ... rice varieties that are better able to cope with ... , The paper, "The genome sequence of African rice ... was published online in Nature Genetics on ...
(Date:7/28/2014)... have pinpointed a mechanism in part of the brain that ... it to both type 1 and type 2 diabetes. The ... Proceedings of the National Academies of Sciences . , ... a part of the hypothalamus known as the ventromedial nucleus ... glucose levels in the blood," said lead author Sabrina Diano, ...
Breaking Biology News(10 mins):Healthy lifestyle may buffer against stress-related cell aging, study says 2Generating a genome to feed the world: UA-led team sequences African rice 2Generating a genome to feed the world: UA-led team sequences African rice 3Generating a genome to feed the world: UA-led team sequences African rice 4Glucose 'control switch' in the brain key to both types of diabetes 2
... dayand starting this week, they will be part of a multinational ... mines left over from as long ago as the First and ... naval exercises in the Baltic Sea this year, where more than ... all part of a day,s work for U.S. Navy divers, who ...
... in air pollution were associated with changes in biomarkers of ... as measures of cardiovascular physiology in healthy young persons, according ... JAMA, a theme issue on Global Health. ... but the mechanisms by which air pollution leads to CVD ...
... A review of studies reporting estimates of the ... malaria over the past 20 years suggests that a ... women attending antenatal (before birth) facilities in sub-Saharan Africa, ... published in the May 16 issue of JAMA ...
Cached Biology News:Undersea warriors, undersea medicine: The future force 2Air pollution level changes in Beijing linked with biomarkers of cardiovascular disease 2Air pollution level changes in Beijing linked with biomarkers of cardiovascular disease 3Air pollution level changes in Beijing linked with biomarkers of cardiovascular disease 4Considerable prevalence of both malaria, STIs exist among pregnant women in sub-Saharan Africa 2
(Date:7/29/2014)... 2014  Pomerantz LLP is investigating claims on behalf ... "Company") (NASDAQ: IPXL).  Such investors are advised to contact ... or 888-476-6529, ext. 237. The investigation concerns ... have violated Sections 10(b) and 20(a) of the Securities ... 29, 2014, Impax Laboratories, Inc. (the "Company") issued a ...
(Date:7/29/2014)... 29, 2014 A new report ... (types, applications and geography) - Size, Share, Global Trends, ... and Forecast, 2013 - 2020", suggests that the global ... by 2020 registering a CAGR of 11.1% from 2014 ... by the electro surgical devices in operative procedures by ...
(Date:7/29/2014)... 2014 Philadelphia’s newest entrepreneurial incubation space is ... start. The Innovation Center @3401 , a collaborative effort ... Science Center to help attract and nurture start-up businesses ... 28. , The Innovation Center @3401 (ic@3401), ... Streets, is the new home of DreamIt Ventures ...
(Date:7/29/2014)... July 29, 2014  United Therapeutics Corporation (NASDAQ: ... financial results for the second quarter ended ... shows that our medicines are reaching increasing ... hypertension (PAH)," said Martine Rothblatt, Ph.D., United ... commercial launch this quarter of our extended-release ...
Breaking Biology Technology:SHAREHOLDER ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of Impax Laboratories, Inc. - IPXL 2Global Surgical Equipment Market is expected to reach $12.1 billion by 2020 - Allied Market Research 2Global Surgical Equipment Market is expected to reach $12.1 billion by 2020 - Allied Market Research 3Innovation Center @3401 Opens for Business; DreamIt Ventures and Point.io First Residents 2Innovation Center @3401 Opens for Business; DreamIt Ventures and Point.io First Residents 3United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 2United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 3United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 4United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 5United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 6United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 7United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 8United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 9United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 10United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 11United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 12United Therapeutics Corporation Reports Second Quarter 2014 Financial Results 13
... Toronto, Ontario - Cedara Software , a ... of medical software technologies, has released a new version ... toolkit, MergeCOM-3. , ,The product is a software development ... and supports flexible DICOM connectivity for software applications. , ...
... into the third year of their Sarbanes-Oxley ... is a good time to pause and reflect on ... on good internal control practices, I hear from hundreds ... how painful implementing 404 has become for their companies. ...
... officials may not be saying it, but they are frightened ... deadly avian flu virus begins quietly in scattered areas of ... on it - with substantial harm done to public health ... one that is exacerbated by the lack of an electronic ...
Cached Biology Technology:The Big Picture of SOX 404 2The Big Picture of SOX 404 3The Big Picture of SOX 404 4UW compound counters Avian flu 2UW compound counters Avian flu 3
Cytofix/Cytoperm Kit 250 Tests...
The BD PhosFlow Fix Buffer I can be used for the simultaneous fixation and permeabilization of cells prior to intracellular staining. Applications: Intracellular Staining (Flow) Storage Temperature:...
... Anti-MAGE-D2/NRAGE-Like 2b GenBank ... Immunogen : peptide (C-QSQENQDTRPKVKAKK), corresponding ... human MAGE-D2/NRAGE-Like 2b Formulation: antiserum ... 30% glycerol Quality Assurance: routinely ...
Request Info...
Biology Products: