Navigation Links
3D X-ray film: Rapid movements in real time

This news release is available in German.

How does the hip joint of a crawling weevil move? A technique to record 3D X-ray films showing the internal movement dynamics in a spatially precise manner and, at the same time, in the temporal dimension has now been developed by researchers at ANKA, KIT's Synchrotron Radiation Source. The scientists applied this technique to a living weevil. From up to 100,000 two-dimensional radiographs per second, they generated complete 3D film sequences in real time or slow motion. The results are now published in the Proceedings of the National Academy of Sciences (PNAS) DOI: 10.1073/pnas.1308650111.

Three-dimensional radiographs represent internal structures, but do not provide any information about movement sequences. Conventional computer tomography is not efficient enough to reproduce movement in a spatially precise manner and, at the same time, in the temporal dimension. Every individual three-dimensional image, called tomogram, is reconstructed from hundreds of two-dimensional radiographs. "To produce highly resolved tomograms at such recording speed, we had to adjust every setting screw, from the X-ray source to the pixel detector and we optimally attuned all process steps to each other," Tomy dos Santos Rolo says. The doctoral student is the leading developer of the experimental setup. By making the 3D image frequencies approach the image rates known for 2D cine films, he reached the world record in high-speed tomography, i.e. a real 3D film with microscopic magnification.

For scientific evaluation, the three-dimensional contours of anatomic structures have to be clearly visible. This is achieved by the so-called phase contrast. If highly parallel X-rays pass the biological examination object, wave optics phenomena occur, which highlight the inner and outer contours.

"It is these contours that matter to us. We want to distinguish individual functional elements that move relative to each other. That is why we need sharp contours," Alexey Ershov, the expert for image analysis in the team, says. From the X-ray source to movement analysis, all process stages are designed to filter out image noise without reducing contrast. This also applies to the mathematic algorithms optimized for radiography. They reconstruct three spatial and one temporal dimension and derive exact movement patterns from the data.

In line with the first moving images cinematography , the scientists call their method "cinetomography". In the late 19th century, movements of big animals were studied. Today, researchers can analyze internal biological processes of small organisms, as is now demonstrated for the recently discovered screw joint of the weevil. Insects, spiders, and crustaceans make up more than 80% of all species.

Cinetomography cannot only be used to image in four dimensions biological and biotechnological processes, but also combustion processes relevant to industry.


Contact: Monika Landgraf
Karlsruher Institut fr Technologie (KIT)

Related biology news :

1. Superbright and fast X-rays image single layer of proteins
2. High-tech X-ray imaging technique to offer detailed look at engineered tissue
3. Scientists prove X-ray laser can solve protein structures from scratch
4. Bringing out the best in X-ray crystallography data
5. X-ray science taps bug biology to design better materials and reduce pollution
6. NLST: CT detects twice as many lung cancers as X-ray at initial screening exam
7. New X-ray method shows how frog embryos could help thwart disease
8. In the blink of an eye: X-ray imaging on the attosecond timescale
9. A dual look at photosystem II using the worlds most powerful X-ray laser
10. Improved X-ray microscopic imaging
11. X-rays reveal uptake of nanoparticles by soya bean crops
Post Your Comments:
Related Image:
3D X-ray film: Rapid movements in real time
(Date:11/17/2015)... , November 17, 2015 ... 19 novembre  2015.  --> Paris , ... --> DERMALOG, le leader de l,innovation biométrique, a ... fois passeports et empreintes sur la même surface de ... passeports et l,autre pour les empreintes digitales. Désormais, un ...
(Date:11/17/2015)... 17, 2015 Pressure BioSciences, Inc. (OTCQB: PBIO) ... and sale of broadly enabling, pressure cycling technology ("PCT")-based ... today announced it has received gross proceeds of $745,000 ... Placement (the "Offering"), increasing the total amount raised to ... additional closings are expected in the near future. ...
(Date:11/12/2015)... 2015  A golden retriever that stayed healthy despite ... has provided a new lead for treating this muscle-wasting ... Institute of MIT and Harvard and the University of ... Cell, pinpoints a protective gene that ... effects. The Boston Children,s lab of Lou Kunkel ...
Breaking Biology News(10 mins):
(Date:11/25/2015)... November 25, 2015 2 nouvelles études ... les différences entre les souches bactériennes retrouvées dans ... des êtres humains . Ces recherches  ouvrent une ... la prise en charge efficace de l,un des ... les chats .    --> 2 nouvelles ...
(Date:11/25/2015)... ... 2015 , ... A long-standing partnership between the Academy of ... formalized with the signing of a Memorandum of Understanding. , AMA Executive Director ... Minter and Capt. Albert Glenn Tuesday, November 24, 2015, at AMA Headquarters in ...
(Date:11/24/2015)... ... November 24, 2015 , ... The United States Golf Association (USGA) ... USGA Green Section Award. Presented annually since 1961, the USGA Green Section Award recognizes ... with turfgrass. , Clarke, of Iselin, N.J., is an extension specialist of ...
(Date:11/24/2015)... ... 24, 2015 , ... International Society for Pharmaceutical Engineering (ISPE) ... annual events for pharmaceutical manufacturing: 2015 Annual Meeting. The conference took place in ... largest number of attendees in more than a decade. , “The 2015 ...
Breaking Biology Technology: