Navigation Links
3-D biomimetic scaffolds support regeneration of complex tissues from stem cells
Date:1/10/2013

New Rochelle, NY, January 10, 2013Stem cells can be grown on biocompatible scaffolds to form complex tissues such as bone, cartilage, and muscle for repair and regeneration of damaged or diseased tissue. However, to function properly, the cells must often grow in a specific pattern or alignment. An innovative method for creating a stretched polymer scaffold that can support complex tissue architectures is described in an article in Tissue Engineering, Part C, Methods, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available on the Tissue Engineering, Part C, Methods website.

Zu-yong Wang and a team of researchers from National University of Singapore, Nanyang Technological University, KK Women's and Children's Hospital, and Duke-NUS Graduate Medical School, in Singapore, developed a reproducible method that involves stretching a polymer thin film to produce scaffolds that can support the growth of human mesenchymal stem cells. The stretching process creates orientated 3-dimensional micro-grooves on the surface of the films, and these formations promote consistent alignment and elongation of stem cells as they grow and develop into tissues on and around the resorbable scaffold.

The authors present their work in the article, "Biomimetic 3D anisotropic geometries by uniaxial stretch of poly(?-caprolactone) films for mesenchymal stem cell proliferation, alignment and myogenic differentiation."

"The researchers developed a very elegant method to promote cell behavior," says John Jansen, DDS, PhD, Methods Co-Editor-in-Chief and Professor and Chairman, Department of Biomaterials, Radboud University Nijmegen Medical Center, The Netherlands.


'/>"/>

Contact: Vicki Cohn
vcohn@liebertpub.com
914-740-2100 x2156
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert  

Page: 1

Related biology news :

1. Slice, stack, and roll: A new way to build collagen scaffolds
2. Nanoscale scaffolds and stem cells show promise in cartilage repair
3. WHOI research projects awarded $5.2 million to support marine microbial research
4. Scale-up of a temporary bioartificial liver support system described in BioResearch Open Access
5. Can algae-derived oils support large-scale, low-cost biofuels production?
6. Combining two genome analysis approaches supports immune system contribution to autism
7. Cargill expands support of Notre Dame Haiti Program
8. BONESUPPORT für 2012 Top 100 Global Award von Red Herring ausgewählt
9. BONESUPPORT sélectionné en tant que 100 meilleures entreprises mondiales du Red Herring 2012
10. BONESUPPORT Selected As A 2012 Red Herring Top 100 Global
11. $1 million Kenan Trust Grant extends support of Scripps Florida education outreach
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
3-D biomimetic scaffolds support regeneration of complex tissues from stem cells
(Date:3/1/2017)...  Aware, Inc. (NASDAQ: AWRE), a leading supplier of ... Moberg has resigned, effective March 3, 2017, as ... and Treasurer of Aware citing a desire to retire.  ... of the Board of Directors of Aware. ... and co-President, General Counsel has been named Chief Executive ...
(Date:2/26/2017)... -- Securus Technologies, a leading provider of civil and ... corrections and monitoring, announces the appointment of a ... often, too many offenders return to jail or ... to tackle this ongoing problem and improve the ... significant steps are underway, Securus continues to invest ...
(Date:2/16/2017)... , Feb. 16, 2017  Genos, a ... announced that it has received Laboratory Accreditation from ... Accreditation is presented to laboratories that meet stringent ... demonstrate scientifically rigorous processes. "Genos is ... in laboratory practices. We,re honored to be receiving ...
Breaking Biology News(10 mins):
(Date:3/29/2017)... 29, 2017 Research and Markets has ... and Global Markets" report to their offering. ... The study ... sequencing, biochips, RNA interference, synthetic biology tools and genome editing ... These technologies and products are analyzed to determine ...
(Date:3/28/2017)... ... 2017 , ... NetDimensions announced today that Scandinavian Health Limited ... management for consistent implementation of standards and regulatory requirements across SHL companies worldwide. ... improve and streamline their training and employee development programs, which are critical to ...
(Date:3/28/2017)... ... March 28, 2017 , ... Benchworks announced that ... Philadelphia. The event was offered by the Chamber of Commerce for Greater Philadelphia ... groups and interaction with speakers who are leaders in their industries. Topics included ...
(Date:3/28/2017)... March 28, 2017 Summary This ... Enzo Biochem and its partnering interests and activities since 2010. ... provides an in-depth insight into the partnering activity of one ... demand company reports are prepared upon purchase to ensure inclusion ... The report will be delivered in PDF format ...
Breaking Biology Technology: