Navigation Links
3-D biomimetic scaffolds support regeneration of complex tissues from stem cells
Date:1/10/2013

New Rochelle, NY, January 10, 2013Stem cells can be grown on biocompatible scaffolds to form complex tissues such as bone, cartilage, and muscle for repair and regeneration of damaged or diseased tissue. However, to function properly, the cells must often grow in a specific pattern or alignment. An innovative method for creating a stretched polymer scaffold that can support complex tissue architectures is described in an article in Tissue Engineering, Part C, Methods, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available on the Tissue Engineering, Part C, Methods website.

Zu-yong Wang and a team of researchers from National University of Singapore, Nanyang Technological University, KK Women's and Children's Hospital, and Duke-NUS Graduate Medical School, in Singapore, developed a reproducible method that involves stretching a polymer thin film to produce scaffolds that can support the growth of human mesenchymal stem cells. The stretching process creates orientated 3-dimensional micro-grooves on the surface of the films, and these formations promote consistent alignment and elongation of stem cells as they grow and develop into tissues on and around the resorbable scaffold.

The authors present their work in the article, "Biomimetic 3D anisotropic geometries by uniaxial stretch of poly(?-caprolactone) films for mesenchymal stem cell proliferation, alignment and myogenic differentiation."

"The researchers developed a very elegant method to promote cell behavior," says John Jansen, DDS, PhD, Methods Co-Editor-in-Chief and Professor and Chairman, Department of Biomaterials, Radboud University Nijmegen Medical Center, The Netherlands.


'/>"/>

Contact: Vicki Cohn
vcohn@liebertpub.com
914-740-2100 x2156
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert  

Page: 1

Related biology news :

1. Slice, stack, and roll: A new way to build collagen scaffolds
2. Nanoscale scaffolds and stem cells show promise in cartilage repair
3. WHOI research projects awarded $5.2 million to support marine microbial research
4. Scale-up of a temporary bioartificial liver support system described in BioResearch Open Access
5. Can algae-derived oils support large-scale, low-cost biofuels production?
6. Combining two genome analysis approaches supports immune system contribution to autism
7. Cargill expands support of Notre Dame Haiti Program
8. BONESUPPORT für 2012 Top 100 Global Award von Red Herring ausgewählt
9. BONESUPPORT sélectionné en tant que 100 meilleures entreprises mondiales du Red Herring 2012
10. BONESUPPORT Selected As A 2012 Red Herring Top 100 Global
11. $1 million Kenan Trust Grant extends support of Scripps Florida education outreach
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
3-D biomimetic scaffolds support regeneration of complex tissues from stem cells
(Date:1/11/2017)... , Jan. 11, 2017 Intoxalock, a leading ... the release of its patent-pending calibration device. With this ... perform calibrations, securely upload data logs and process repairs ... customer. "Fighting drunk driving through the application ... public at large, but also for the customer who ...
(Date:1/6/2017)... NEWARK, Calif. , Jan. 5, 2017  Delta ... introduced its iris scanning technology for automotive at CES® ... GNTX ) to demonstrate the use of ... to identify and authenticate the driver in a car, ... automobiles during the driving experience. Delta ID ...
(Date:12/22/2016)... Dec. 20, 2016  As part of its longstanding mission ... personal genetics company, recently released its latest children,s book, titled ... book focuses on the topics of inheritance and variation of ... (NGSS) taught in elementary school classrooms in the US. ... by illustrator Ariana Killoran , whose previous book with ...
Breaking Biology News(10 mins):
(Date:1/18/2017)... -- Market Research Future published a half-cooked research report on Global Cancer ... a CAGR of 12% during the period 2016 to 2022. ... ... division without any control. These abnormal cells have the ability to ... can spread to other parts of the body through the blood ...
(Date:1/17/2017)... ... January 17, 2017 , ... MS ... The new Balance™ GT Soybean Performance System will combine industry-leading genetics with a ... ingredient in the new Balance® Bean herbicide. The Balance™ GT Soybean Performance System ...
(Date:1/17/2017)... SAN DIEGO , Jan. 17, 2017 /PRNewswire/ ... Diego School of Medicine and St. Boniface Hospital ... treatments for peripheral neuropathy, an unmet health need ... in the Journal of Clinical Investigation, their results ... properties that prevent and reverse neuronal injury in ...
(Date:1/17/2017)...  Zimmer Biomet Holdings, Inc. (NYSE and SIX: ZBH) ... and earnings conference call will be broadcast live over ... a.m. Eastern Time.  A news release detailing the quarterly ... a.m. Eastern Time the morning of the conference call. ... via Zimmer Biomet,s Investor Relations website at http://investor.zimmerbiomet.com ...
Breaking Biology Technology: