Navigation Links
3-D biomimetic scaffolds support regeneration of complex tissues from stem cells
Date:1/10/2013

New Rochelle, NY, January 10, 2013Stem cells can be grown on biocompatible scaffolds to form complex tissues such as bone, cartilage, and muscle for repair and regeneration of damaged or diseased tissue. However, to function properly, the cells must often grow in a specific pattern or alignment. An innovative method for creating a stretched polymer scaffold that can support complex tissue architectures is described in an article in Tissue Engineering, Part C, Methods, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. The article is available on the Tissue Engineering, Part C, Methods website.

Zu-yong Wang and a team of researchers from National University of Singapore, Nanyang Technological University, KK Women's and Children's Hospital, and Duke-NUS Graduate Medical School, in Singapore, developed a reproducible method that involves stretching a polymer thin film to produce scaffolds that can support the growth of human mesenchymal stem cells. The stretching process creates orientated 3-dimensional micro-grooves on the surface of the films, and these formations promote consistent alignment and elongation of stem cells as they grow and develop into tissues on and around the resorbable scaffold.

The authors present their work in the article, "Biomimetic 3D anisotropic geometries by uniaxial stretch of poly(?-caprolactone) films for mesenchymal stem cell proliferation, alignment and myogenic differentiation."

"The researchers developed a very elegant method to promote cell behavior," says John Jansen, DDS, PhD, Methods Co-Editor-in-Chief and Professor and Chairman, Department of Biomaterials, Radboud University Nijmegen Medical Center, The Netherlands.


'/>"/>

Contact: Vicki Cohn
vcohn@liebertpub.com
914-740-2100 x2156
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert  

Page: 1

Related biology news :

1. Slice, stack, and roll: A new way to build collagen scaffolds
2. Nanoscale scaffolds and stem cells show promise in cartilage repair
3. WHOI research projects awarded $5.2 million to support marine microbial research
4. Scale-up of a temporary bioartificial liver support system described in BioResearch Open Access
5. Can algae-derived oils support large-scale, low-cost biofuels production?
6. Combining two genome analysis approaches supports immune system contribution to autism
7. Cargill expands support of Notre Dame Haiti Program
8. BONESUPPORT für 2012 Top 100 Global Award von Red Herring ausgewählt
9. BONESUPPORT sélectionné en tant que 100 meilleures entreprises mondiales du Red Herring 2012
10. BONESUPPORT Selected As A 2012 Red Herring Top 100 Global
11. $1 million Kenan Trust Grant extends support of Scripps Florida education outreach
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
3-D biomimetic scaffolds support regeneration of complex tissues from stem cells
(Date:6/20/2016)... -- Securus Technologies, a leading provider of civil ... investigation, corrections and monitoring announced that after exhaustive ... the final acceptance by all three (3) Department ... (MAS) installed. Furthermore, Securus will have contracts for ... October, 2016. MAS distinguishes between legitimate wireless device ...
(Date:6/9/2016)... June 9, 2016 Paris ... Teleste,s video security solution to ensure the safety of people ... during the major tournament Teleste, an international ... and services, announced today that its video security solution will ... to back up public safety across the country. The system ...
(Date:6/2/2016)... , June 2, 2016   The Weather Company , ... Watson Ads, an industry-first capability in which consumers will be ... able to ask questions via voice or text and receive ... Marketers have long sought an advertising ... that can be personal, relevant and valuable; and can scale ...
Breaking Biology News(10 mins):
(Date:12/5/2016)... December 5, 2016 According ... Market, by Products (Consumable, Instruments, Automated Cell Expansion ... and Stem Cell Research, Cancer, and Cell-Based Research), ... Banks) - Global Revenue, Trends, Growth, Share, Size ... Research, the global cell expansion market is expected ...
(Date:12/5/2016)... Mich. , Dec. 5, 2016 NxGen MDx announced today ... bringing the test in house, we,ve been able to improve customer service ... for patients," says Alan Mack , CEO of NxGen MDx. ... , , ... test volume has led to more job opportunities at the Grand Rapid ...
(Date:12/5/2016)... , December 5, 2016 The ... with almost $108 billion of revenue and some $890 ... were spent on global biopharmaceuticals, and this figure is ... Stock-Callers.com has lined up these four equities for assessment: ... Pharmaceuticals Inc. (NASDAQ: ACAD ), Acorda Therapeutics ...
(Date:12/4/2016)... , Dec. 3, 2016  In five studies ... Hematology (ASH) Annual Meeting and Exposition in ... engineering methods to improve the delivery of life-saving treatments ... new methods are designed to carry therapies directly to ... most, which could provide a substantial advantage over traditional, ...
Breaking Biology Technology: