Navigation Links
25 years of DNA on the computer
Date:1/3/2014

DNA carries out its activities "diluted" in the cell nucleus. In this state it synthesises proteins and, even though it looks like a messy tangle of thread, in actual fact its structure is governed by precise rules that are important for it to carry out its functions. Biologists have studied DNA by observing it experimentally with a variety of techniques, which have only recently been supplemented by research in silico, that is to say, the study of DNA by means of computer simulations. This is a recent area of study, but it has already given a major contribution to knowledge in this field. Angelo Rosa, a theoretical physicist of the International School for Advanced Studies (SISSA) in Trieste, with the collaboration of Christophe Zimmer, an experimental physicist from the Pasteur Institute in Paris has assessed the state of the art of this novel but powerful approach in a systematic review that has just been published in the journal International Review of Cell and Molecular Biology.

"Apart from some rare exceptions, we reviewed virtually all of the models developed to date", explains Rosa. "The review is mainly aimed at biologists in that we have made minimal use of mathematical formulas which hamper reading. I think this is the first review of its kind. The paper is actually also interesting for physicists and mathematicians who are approaching this new field for the first time".

The two physicists reviewed 25 years of computational models: "in this relatively short time span the models have become increasingly sophisticated and this, thanks to the development of computers", explains Rosa. "Today we are able to make far more detailed and predictive simulations, which allow us to lead the work of experimental researchers in previously unthought-of directions".

"This is a useful tool which, without going into mathematical detail, provides the biologist with an overview of the type of studies that will increasingly compleme
'/>"/>

Contact: Federica Sgorbissa
comunicazione@medialab.sissa.it
39-040-378-7644
International School of Advanced Studies (SISSA)
Source:Eurekalert  

Page: 1 2

Related biology news :

1. Oceans acidifying faster today than in past 300 million years
2. Ice sheet collapse and sea-level rise at the Boelling warming 14,600 years ago
3. 50 years of bird poop links DDT with changing bird menus
4. UH makes Princeton Reviews Green List 3 years in a row
5. Global warming has driven Europes mountain plants to migrate 2.7 meters upwards in 7 years
6. Jurassic pain: Giant flea-like insects plagued dinosaurs 165 million years ago
7. Scientists read the ash from the Icelandic volcano 2 years after its eruption
8. Special issue of the EMBO Journal celebrates 30 years of Wnt research
9. 10 million years to recover from mass extinction
10. Development of prosthetic hands stagnated for 20 years
11. Over 30 years of global soil moisture observations for climate applications
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
25 years of DNA on the computer
(Date:7/11/2014)... University of Chicago is creating a new professorship ... the University,s Institute for Molecular Engineering and the ... donation from the Millicent and Eugene Bell Foundation., ... reside within the Institute for Molecular Engineering. That ... project at the MBL,s Eugene Bell Center for ...
(Date:7/11/2014)... 3, 2014, Shenzhen, China Researchers from Salk Institute ... the first time evaluated the safety and reliability ... successfully developed a new method, TALEN-HDAdV, which could ... stem cell (hiPSC). This study published online in ... theoretical foundation for stem cell-based gene therapy. , ...
(Date:7/11/2014)... 11, 2014 The increased risk of kidney injury ... resuscitation fluids reflects the mass of HES molecules, according ... official journal of the International Anesthesia Research Society (IARS). ... harmful effect of HES on cultured human renal proximal ... Christian Wunder and colleagues of University Hospital Wrzburg, Austria. ...
Breaking Biology News(10 mins):New professorship in tissue engineering links molecular engineering, marine biology 2A new genome editing method brings the possibility of gene therapies closer to reality 2In lab studies, hydroxyethyl starch has direct harmful effects on kidney cells 2
... from blood poisoning? To answer this question, the doctor draws ... for testing. This takes up valuable time, which could cost ... to analyze blood there and then and have the results ... developed by scientists at the Fraunhofer Institute for Physical Measurement ...
... considering scores of applications to develop utility-scale solar power ... but too little is known to judge their likely ... the December 2011 issue of BioScience . Although ... technology, available information suggests a worrisome range of possible ...
... ARLINGTON, Va.Underscoring the importance of alternative energy for the ... Corps Base Hawaii Dec. 7 to learn about possible ... Research (ONR)-funded fuel cell vehicles (FCV) and high-efficiency trash ... the 70th anniversary of the Pearl Harbor attack, was ...
Cached Biology News:Recognizing blood poisoning quickly 2Solar power development in US Southwest could threaten wildlife 2New energy sources fuel interest from Secretary of the Navy 2
(Date:7/10/2014)... PROVO, Utah , July 10, 2014 ... genome annotation and interpretation, today announced an ... sequencing (NGS) analytics for Lineagen,s NextStep Dx ... evaluation of neurodevelopmental and neurological disorders, currently ... chromosomal microarray (CMA) testing service used by ...
(Date:7/10/2014)... --  Ceres, Inc . (Nasdaq: CERE ), ... results for the three months ended May 31, 2014 ... Ceres reported that the company and its customers have ... in Brazil, which concluded in June, despite dry and ... for part of the growing season. Yields of several ...
(Date:7/10/2014)... research may help in the fight against terrorism with ... quantities of explosives with the use of light and ... Sensors and Actuators B: Chemical , the researchers describe ... in concentrations as low as 6.3 ppm (parts per ... few minutes. , "Traditionally explosives detection has involved looking ...
(Date:7/10/2014)... journal PNAS (Proceedings of the National Academy of ... sleep deprivation have a significant effect on our metabolism. ... best time of day to test for diseases such ... effectively. , Researchers from the University of Surrey and ... between sleep deprivation, body clock disruption and metabolism, and ...
Breaking Biology Technology:Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 2Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 3Tute Genomics Platform Selected to Provide Clinical Interpretation for Lineagen's NextStepDx PLUS Next-Generation Sequencing-Based Diagnostic Test 4Ceres Announces Fiscal Third Quarter 2014 Financial Results 2Ceres Announces Fiscal Third Quarter 2014 Financial Results 3Ceres Announces Fiscal Third Quarter 2014 Financial Results 4Ceres Announces Fiscal Third Quarter 2014 Financial Results 5Ceres Announces Fiscal Third Quarter 2014 Financial Results 6Ceres Announces Fiscal Third Quarter 2014 Financial Results 7Ceres Announces Fiscal Third Quarter 2014 Financial Results 8Ceres Announces Fiscal Third Quarter 2014 Financial Results 9Detecting trace amounts of explosives with light 2Time of day crucial to accurately test for diseases, new research finds 2
... , SEATTLE, Sept. 10 Cell Therapeutics, Inc. ... the Biotech Industry conference on Wednesday, September 16, 2009, at 10:30 AM ... 16, 2009, at the Millennium Broadway Hotel in New York. The ... the presentation. The webcast can be accessed at www.celltherapeutics.com ...
... , CARLISLE, Pa., Sept. 9 Hanson ... pathogen screening, today announced the issuance of a U.S. Patent ... Microorganisms. The U.S. patent describes the Company,s method for screening ... and other plant material intended for human and animal consumption. ...
... , CAMBRIDGE, Mass., Sept. 9 ... development of next-generation cellulosic ethanol and high-performance specialty enzymes, announced that ... at 5:00 p.m. today. Verenium,s shares will continue to trade ... letter "D" added to the end of the trading symbol for ...
Cached Biology Technology:Hanson Technologies, Inc. Awarded Patent for its Advanced Food Pathogen Detection System 2Verenium 1:12 Reverse Stock Split Takes Effect 2Verenium 1:12 Reverse Stock Split Takes Effect 3Verenium 1:12 Reverse Stock Split Takes Effect 4
... Jouan MSC series of Class II ... conditions and certification to the world's ... ensures that the cabinets cannot be ... Natural lighting, low noise and arm ...
... to create the ideal environment for nucleic acid ... , Variable speed control (10 to 15 ... be for washing or hybridizing , A ... the chamber, ,is situated above a touch sensitive ...
... engineered for efficient drying down of synthetic ... cover and a post-trap with ammonia neutralizing ... of samples in ammonium hydroxide., , ... , Comes standard with ...
... MB (for aqueous, other low volatility and ... respond to specific applications of molecular biology ... of heat-labile samples. The RC systems can ... traps and a wide selection of rotors ...
Biology Products: