Navigation Links
23andMe presents top 10 most interesting genetic findings of 2010
Date:1/12/2011

at is highly expressed in the brain and known to be important in processes that are disrupted by the plaques that form in the brains of people with Alzheimer's. Two of the genes near rs597668, BLOC1S3 and MARK4, encode brain proteins that are also involved in processes that are disrupted in Alzheimer's disease. The MARK4 protein in particular is interesting because it interacts with tau, the protein responsible for the tangles seen in the brains of people with Alzheimer's.

Although risk models that incorporated an individual's information for the two replicated CLU and PICALM gene regions did not substantially improve prediction compared to a traditional model using only APOE status, age and sex, Nancy Pedersen of the Karolinska Institute in Sweden, points out in an accompanying editorial that this finding is not surprising given the small effect of these SNPs on risk and "only verifies the notion that AD is a polygenic disorder; i.e., that potentially tens of thousands of risk alleles, each with a small effect, are important for liability to disease. What is remarkable is that the single gene APOE is as important as it is for this complex disorder, and that right now, the most important thing doctors can do is encourage people to make lifestyle changes, especially those that improve cardiovascular health, that may reduce the risk of dementia or at least postpone it."

"SNPwatch: Large Study Identifies Two More Genetic Variants Associated with Alzheimer's Disease." May 11, 2010. The Spittoon. http://spittoon.23andme.com/2010/05/11/snpwatch-large-study-identifies-two-more-genetic-variants-associated-with-alzheimers-disease/

"SNPwatch: Largest Alzheimer's Genetic Studies To Date Identify Three New Susceptibility Genes." Sep 8, 2009. The Spittoon.

Contact: Jane E. Rubinstein
jrubinstein@rubenstein.com
212-843-8287
23andMe Inc.
Source:Eurekalert  

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18

Related biology news :

1. 23andMe receives NIH funding to evaluate web-based research on the genetics of drug response
2. Colossal fossil: Museums new whale skeleton represents decades of research
3. UC doctoral student presents research at international conference
4. American Society of Agronomy presents 2010 Fellows
5. AMP presents at FDA meeting on regulating diagnostics
6. AAPS presents therapeutic protein drug interactions workshop
7. ASNTR meeting presents Sanberg Awards to Prof. Lin & Prof. Dunnett
8. Latino Theater Company Presents Dementia Starting April 29
9. Hormone sensitivity of breast stem cells presents drug target
10. NYU School of Medicine presents biomedical researchers Dart/NYU Biotechnology Achievement Awards
11. P&G Beauty & Grooming presents advancements in skin care at AAD Annual Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
23andMe presents top 10 most interesting genetic findings of 2010
(Date:4/17/2014)... bone marrow need to produce hydrogen sulfide in order ... a new study from the Center for Craniofacial Molecular ... USC. , Professor Songtao Shi, principal investigator on the ... the cells governs the flow of calcium ions. The ... results in osteogenesis, or the creation of new bone ...
(Date:4/17/2014)... fragmentation of forests in the Amazon help create ... to rapid and widespread forest loss during drought ... findings show that forests in the Amazon could ... with forest fires lead to large-scale loss of ... assistant professor of geography, Penn State. , "We ...
(Date:4/17/2014)... have detected new early-warning signs of the potential loss ... far-reaching implications for the diagnosis and treatment of diabetic ... Americans. , "We had not expected to see such ... said Ann Elsner, professor and associate dean in the ... study. "We set out to study the early signs, ...
Breaking Biology News(10 mins):Drought and fire in the Amazon lead to sharp increases in forest tree mortality 2Drought and fire in the Amazon lead to sharp increases in forest tree mortality 3New technique detects microscopic diabetes-related eye damage 2New technique detects microscopic diabetes-related eye damage 3
... Angeles, Calif., May 22, 2011Some men of African descent may ... to research conducted at the Keck School of Medicine of ... study, published in the journal Nature Genetics on ... in men of African descent, who tend to more susceptible ...
... Researchers from the Centers for Disease Control and ... to prion diseases, looking at hunting, venison consumption, and ... reported in animals. Three prion diseases in particular ... Creutzfeldt-Jakob disease (vCJD), and chronic wasting disease (CWD) ...
... forces that guide how cells migratehow they manage to get ... living body are poorly understood. Scientists at the Harvard School ... Catalonia (IBEC) have, for the first time, devised a way ... conclusion is that the cells fight it out, each pushing ...
Cached Biology News:USC research determines apparent genetic link to prostate cancer in African-American men 2CDC assesses potential human exposure to prion diseases 2CDC assesses potential human exposure to prion diseases 3The dance of the cells: A minuet or a mosh? 2The dance of the cells: A minuet or a mosh? 3
(Date:1/15/2014)... , Jan. 15, 2014 ­ RedBrick Health ... behavior change technology, today announces that EmblemHealth , ... and wellness company, is now providing the RedBrick Compass ... coaching program, to all of its members. EmblemHealth is ...
(Date:1/15/2014)... Reston, VA (PRWEB) January 15, 2014 ... education have continued their sponsorship of an annual competition ... interest in, and access to, innovative STEM study. The ... , TEAMS: Tests of Engineering Aptitude, Mathematics, and ...
(Date:1/15/2014)... 2014 Freeslate, Inc ., the ... that Lupin Limited, one of India’s top five pharmaceutical ... PharmD System for high throughput solid form screening. ... on a wide range of quality, affordable generic and ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 Carahsoft and ... Thursday, January 23, 2014 at 2pm EST (11am PST), ... The topic focuses on how technology can turn raw, ... decisions for government agencies. The online webinar will last ...
Breaking Biology Technology:EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 2EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 3Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 2Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 3Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 4Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 5Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 2Lupin Selects Freeslate’s CM Protégé PharmD System to Accelerate Polymorph Screening for Drug Development 3Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2
... Quest Diagnostics Incorporated (NYSE: DGX ), the world,s ... the final results for its previously announced cash tender offer ... (the "Tender Cap") of its 5.125% Senior Notes due 2010 ... The terms and conditions of the tender offer are described ...
... /PRNewswire-FirstCall/ - BioSyntech, Inc. (TSX: BSY), a biotechnology ... announced statistically significant results from an analysis of ... the BST-CarGel(R) randomized clinical trial. Specifically, statistically significant ... BST-CarGel treatment was found during analyses of tissues ...
... for Discovery and Validation of New Biomarker Panels ... Rules-Based Medicine, Incorporated (RBM), the world,s leading multiplexed ... the most comprehensive collection of quantitative immunoassays for ... drug and diagnostic development. The new service, DiscoveryMAP(TM) ...
Cached Biology Technology:Quest Diagnostics Announces Final Tender Offer Results 2Quest Diagnostics Announces Final Tender Offer Results 3BioSyntech Reports Positive Results from Pivotal Trial for BST-CarGel(R) Cartilage Repair Device 2BioSyntech Reports Positive Results from Pivotal Trial for BST-CarGel(R) Cartilage Repair Device 3BioSyntech Reports Positive Results from Pivotal Trial for BST-CarGel(R) Cartilage Repair Device 4BioSyntech Reports Positive Results from Pivotal Trial for BST-CarGel(R) Cartilage Repair Device 5Rules-Based Medicine, Inc. Launches DiscoveryMAP(TM) Service for Drug and Diagnostic Development 2Rules-Based Medicine, Inc. Launches DiscoveryMAP(TM) Service for Drug and Diagnostic Development 3
Peptide-affinity Purified Polyclonal Antibody to ICEBERG Peptide with sequence EEDPQLASKMGLH, from C Terminus of the protein sequence according to NP_067546...
A431 cells Source: Cell Lysate Form: Ready to Use Application: Western Blotting Control...
Madin-Darby bovine kidney (MDBK) cells Source: Cell Lysate Form: Ready to Use Application: Western Blotting Control...
... Mutation Explorer processes up to 48 ... traces. Data input can be from either ... terminator or primer chemistries. The detection parameters ... analyst to analyst consistency. We have ...
Biology Products: