Bryc K et al. (2010) Genome-wide patterns of population structure and admixture among Hispanic/Latino populations. Proc Natl Acad Sciences. 107(S2):8954-8961.
10. Web-based research works!
It was a great year for 23andMe, as it proudly announced that its new web-based research paradigm (23andWe) works and unveiled its first peer-reviewed scientific study. The results, published last spring in PLoS Genetics, encompassed replications of previous findings as well as newly discovered genetic associations. 23andWe is a web-based, participant-driven research framework designed to facilitate the rapid recruitment and phenotyping of participants for many studies at once, thus reducing the time and money needed to make new discoveries. In this peer-reviewed paper 23andMe confirmed that self-reported data from customers has the potential to yield data of comparable quality as data gathered using traditional research methods, moving scientific research forward, faster.
Over 9,000 people contributed data to the study of 22 separate traits. Novel SNP associations were revealed for hair curl, asparagus anosmia (the inability to detect the scent of certain asparagus metabolites in urine), the photic sneeze reflex (the tendency to sneeze when entering bright light), and freckling. Previously identified genetic associations between nine genes and certain pigmentation-related traits (hair color, eye color, and freckling) were replicated.
At the annual American Society of Human Genetics meeting in November, 23andMe scientists also announced preliminary results from several studies, including research into the genetics of Parkinson's disease, infectious disease and physical traits; accuracy and performance of modeling risk using common genetic variants; and replication of additional ge
|Contact: Jane E. Rubinstein|