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23andMe presents top 10 most interesting genetic findings of 2010
Date:1/12/2011

f the results of this study will not have the same longevity as its participants. In genetics, as with most things in life, if a result seems too good to be true, it probably is. That said, the study did contain some interesting tidbits, such as the association of rs2075650 near the APOE gene with longevity. This gene is an established susceptibility gene for Alzheimer's disease.

"SNPwatch: Uncertainty Surrounds Longevity GWAS." Jul 17, 2010. The Spittoon. http://spittoon.23andme.com/2010/07/07/snpwatch-uncertainty-surrounds-longevity-gwas/

Sebastiani P et al. (2010) Genetic Signatures of Exceptional Longevity in Humans. Science. Published Online Jul 1 2010, doi: 10.1126/science.1190532

Newman AB et al. (2010) A Meta-analysis of Four Genome-Wide Association Studies of Survival to 90 Years or Older: The Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium. J Gerontol A Biol Sci Med Sci. 65A(5): 478-487.

7. Baby's First Tooth May Be A Health Predictor

Some 23andMe SNPwatches focus not on what's new to be learned in your personal genetic data, but on what we can learn about human development and health through genetics. So it was fascinating to learn that baby's first tooth is more than a life event to post on Facebook or share with the grandparents. This year SNPwatch shared how researchers identified several genetic variations associated with the timing of a baby's first tooth and the number of teeth at age one as published in the journal PLoS Genetics.

All of the SNPs associated with first tooth eruption and teeth at age 1, which were identified in this study of 6,000 people who had been followed by epidemiologists since early in their mothers' pregnancies, are located in or around genes known to have roles in organ formation, growth and development, or cancer, thus suggesting that studies of
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Contact: Jane E. Rubinstein
jrubinstein@rubenstein.com
212-843-8287
23andMe Inc.
Source:Eurekalert  

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