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21st century vaccines -- innovation in design and rational use
Date:9/23/2011

and population differences in immune responses to vaccines. Vaccinomics holds great promise for the design of safer and more effective vaccines, and their targeted rational use via novel postgenomics diagnostics to prevent and combat infectious diseases, and to intervene in chronic non-communicable diseases such as cancer, diabetes, and obesity.

Featuring global contributions from leading experts in Australia, Asia, Europe, and North America, "Vaccines of the 21st Century: Vaccinomics for Global Public Health" includes a series of articles on cutting-edge topics such as the conceptual basis of vaccinomics; high throughput ''game changing'' experimental approaches for 21st century vaccine design; case studies including previously neglected tropical diseases vastly affecting the developing countries (e.g., vaccinomics for helminth infections); the new therapeutic cancer vaccines; social science and policy analyses on vaccinomics and global health convergence, and the current strategies for vaccinomics-enabled rational vaccine design deployed by the vaccine industry.

An opinion piece by Alan Bernstein, Global HIV Vaccine Enterprise (New York, NY), Bali Pulendran, Emory University School of Medicine (Atlanta, GA), and Rino Rappuoli, Novartis Global Vaccines and Diagnostics (Siena, Italy) provides a forward look in the article "Systems Vaccinomics: The Road Ahead for Vaccinology."

Guest Editor Vural Ozdemir notes that "OMICS technologies and postgenomics diagnostics, when considered under a sound public health genomics framework, can offer innovative and potentially cost-effective solutions to current priorities in global health." In a concluding remark, he observes that the new science demands more than technological proficiency: "Seeking science-based solutions such as vaccinomics for the extant global public health priorities can only be achieved in a sustainable manner through a tri-partite integration of the biological, social, and pol
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Contact: Vicki Cohn
vcohn@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert  

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