Navigation Links
21st century vaccines -- innovation in design and rational use
Date:9/23/2011

New Rochelle, NY, September 22, 2011Innovation in the design of vaccines is rapidly expanding their use, safety, and effectiveness for disease prevention and therapeutic interventions. The enormous potential of OMICS sciences for global health and vaccine design is examined in "Vaccines of the 21st Century and Vaccinomics," a special issue of OMICS: A Journal of Integrative Biology, the peer-reviewed journal published by Mary Ann Liebert, Inc. The issue is available free online.

"Truly a fresh new look at how we design vaccines and apply them judiciously to benefit global health is essential and timely in the present age of data enabled science and postgenomics integrative biology," writes Eugene Kolker, PhD, Editor-in-Chief of OMICS, and Chief Data Officer, Seattle Children's Hospital, and Head, Bioinformatics & High-Throughput Analysis Laboratory, Seattle Children's Research Institute, and the Special Issue Guest Editor Vural Ozdemir (Associate Professor, McGill University, Canada), and co-authors of the Introductory Editorial, Tikki Pang (World Health Organization, Geneva, Switzerland), Bartha M. Knoppers, Denise Avard, Ma'n H. Zawati (Centre of Genomics and Policy, Department of Human Genetics, Faculty of Medicine, McGill University), and Samer A. Faraj (Desautels Faculty of Management, McGill University).

Despite advances in public health in the 21th century, we still lack safe and highly effective vaccines against the common pathogens seriously affecting global society such as neglected tropical diseases and helminth infections, tuberculosis, HIV, and malaria. These gaps in global health are deepened further by the lack of development of new antimicrobial drugs. The new field of vaccinomics relies on the integrated use of multi-omics data intensive biotechnologies (e.g., genomics, proteomics, metabolomics) to understand individual and population differences in immune responses to vaccines. Vaccinomics holds great promise for the design of safer and more effective vaccines, and their targeted rational use via novel postgenomics diagnostics to prevent and combat infectious diseases, and to intervene in chronic non-communicable diseases such as cancer, diabetes, and obesity.

Featuring global contributions from leading experts in Australia, Asia, Europe, and North America, "Vaccines of the 21st Century: Vaccinomics for Global Public Health" includes a series of articles on cutting-edge topics such as the conceptual basis of vaccinomics; high throughput ''game changing'' experimental approaches for 21st century vaccine design; case studies including previously neglected tropical diseases vastly affecting the developing countries (e.g., vaccinomics for helminth infections); the new therapeutic cancer vaccines; social science and policy analyses on vaccinomics and global health convergence, and the current strategies for vaccinomics-enabled rational vaccine design deployed by the vaccine industry.

An opinion piece by Alan Bernstein, Global HIV Vaccine Enterprise (New York, NY), Bali Pulendran, Emory University School of Medicine (Atlanta, GA), and Rino Rappuoli, Novartis Global Vaccines and Diagnostics (Siena, Italy) provides a forward look in the article "Systems Vaccinomics: The Road Ahead for Vaccinology."

Guest Editor Vural Ozdemir notes that "OMICS technologies and postgenomics diagnostics, when considered under a sound public health genomics framework, can offer innovative and potentially cost-effective solutions to current priorities in global health." In a concluding remark, he observes that the new science demands more than technological proficiency: "Seeking science-based solutions such as vaccinomics for the extant global public health priorities can only be achieved in a sustainable manner through a tri-partite integration of the biological, social, and political determinants of health."


'/>"/>

Contact: Vicki Cohn
vcohn@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert  

Related biology news :

1. Bringing botany into the 21st Century
2. Penn study shows an ancient crop effective in protecting against a 21st century hazard
3. Human influence on the 21st century climate: 1 possible future for the atmosphere
4. Illuminating life: How RNA, after a century in the shadows, emerged into the spotlight
5. Renaissance of 200-year old technology could ease 21st century sustainability challenges
6. Shrinking tundra, advancing forests: how the Arctic will look by centurys end
7. Captain Scotts century-old collections suggests marine life is capturing more carbon
8. More than 31 freshwater species have moved to Galicia over past century
9. A plan to promote sustainable US scientific discovery and innovation in the 21st century is proposed in OMICS
10. New study reveals decline of marine phytoplankton over the past century
11. Leaded gasoline predominant source of lead exposure in latter 20th century
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
21st century vaccines -- innovation in design and rational use
(Date:1/15/2016)... Rico , Jan. 15, 2016 Recent ... and small to find new ways to ensure data ... iOS and Android that ... on biometrics, transforming it into a hardware authorization token. ... users swipe their fingerprint on their KodeKey enabled device ...
(Date:1/13/2016)... 13, 2016 ... of the  "India Biometrics Authentication & ... (2015-2020)"  report to their offering.  ... announced the addition of the  "India ... Estimation & Forecast (2015-2020)"  report ...
(Date:1/11/2016)... , Jan. 11, 2016  higi, the leading ... 10,000 retail locations, web and mobile, today announced ... million from existing investors. --> ... devoted to further innovate higi,s health platform – ... web portal – including expanding services and programs ...
Breaking Biology News(10 mins):
(Date:2/10/2016)... ... February 10, 2016 , ... HOLLOWAY AMERICA, a leading ... (ISPE) Rocky Mountain Chapter 21st Annual Vendor Exhibition on Thursday, February 18, 2016. ... tables for its annual event, which will run from 3:00 p.m. - 8:30 ...
(Date:2/10/2016)... ... February 10, 2016 , ... PatientCrossroads announces ... the secure online PatientCrossroads platform, has exceeded both its one-year and overall recruitment ... PROMPT study, which seeks to advance understanding of the hereditary risks for certain ...
(Date:2/10/2016)... ... , ... Cenna Bioscience Inc., an emerging biopharmaceutical company focused on the discovery ... has been selected to present at the Cavendish Global Health Impact Forum taking place ... purpose of the Forum is to help family offices and foundations develop and implement ...
(Date:2/9/2016)... Feb. 9, 2016  Regenicin, Inc. (OTC Bulletin ... in the development and commercialization of regenerative cell ... and organs, recently reported the Company,s operating results ... of 2016. Lonza America , Inc. ... fiscal year in the process of consummating an ...
Breaking Biology Technology: