Navigation Links
21st century vaccines -- innovation in design and rational use
Date:9/23/2011

New Rochelle, NY, September 22, 2011Innovation in the design of vaccines is rapidly expanding their use, safety, and effectiveness for disease prevention and therapeutic interventions. The enormous potential of OMICS sciences for global health and vaccine design is examined in "Vaccines of the 21st Century and Vaccinomics," a special issue of OMICS: A Journal of Integrative Biology, the peer-reviewed journal published by Mary Ann Liebert, Inc. The issue is available free online.

"Truly a fresh new look at how we design vaccines and apply them judiciously to benefit global health is essential and timely in the present age of data enabled science and postgenomics integrative biology," writes Eugene Kolker, PhD, Editor-in-Chief of OMICS, and Chief Data Officer, Seattle Children's Hospital, and Head, Bioinformatics & High-Throughput Analysis Laboratory, Seattle Children's Research Institute, and the Special Issue Guest Editor Vural Ozdemir (Associate Professor, McGill University, Canada), and co-authors of the Introductory Editorial, Tikki Pang (World Health Organization, Geneva, Switzerland), Bartha M. Knoppers, Denise Avard, Ma'n H. Zawati (Centre of Genomics and Policy, Department of Human Genetics, Faculty of Medicine, McGill University), and Samer A. Faraj (Desautels Faculty of Management, McGill University).

Despite advances in public health in the 21th century, we still lack safe and highly effective vaccines against the common pathogens seriously affecting global society such as neglected tropical diseases and helminth infections, tuberculosis, HIV, and malaria. These gaps in global health are deepened further by the lack of development of new antimicrobial drugs. The new field of vaccinomics relies on the integrated use of multi-omics data intensive biotechnologies (e.g., genomics, proteomics, metabolomics) to understand individual and population differences in immune responses to vaccines. Vaccinomics holds great promise for the design of safer and more effective vaccines, and their targeted rational use via novel postgenomics diagnostics to prevent and combat infectious diseases, and to intervene in chronic non-communicable diseases such as cancer, diabetes, and obesity.

Featuring global contributions from leading experts in Australia, Asia, Europe, and North America, "Vaccines of the 21st Century: Vaccinomics for Global Public Health" includes a series of articles on cutting-edge topics such as the conceptual basis of vaccinomics; high throughput ''game changing'' experimental approaches for 21st century vaccine design; case studies including previously neglected tropical diseases vastly affecting the developing countries (e.g., vaccinomics for helminth infections); the new therapeutic cancer vaccines; social science and policy analyses on vaccinomics and global health convergence, and the current strategies for vaccinomics-enabled rational vaccine design deployed by the vaccine industry.

An opinion piece by Alan Bernstein, Global HIV Vaccine Enterprise (New York, NY), Bali Pulendran, Emory University School of Medicine (Atlanta, GA), and Rino Rappuoli, Novartis Global Vaccines and Diagnostics (Siena, Italy) provides a forward look in the article "Systems Vaccinomics: The Road Ahead for Vaccinology."

Guest Editor Vural Ozdemir notes that "OMICS technologies and postgenomics diagnostics, when considered under a sound public health genomics framework, can offer innovative and potentially cost-effective solutions to current priorities in global health." In a concluding remark, he observes that the new science demands more than technological proficiency: "Seeking science-based solutions such as vaccinomics for the extant global public health priorities can only be achieved in a sustainable manner through a tri-partite integration of the biological, social, and political determinants of health."


'/>"/>

Contact: Vicki Cohn
vcohn@liebertpub.com
914-740-2100
Mary Ann Liebert, Inc./Genetic Engineering News
Source:Eurekalert  

Related biology news :

1. Bringing botany into the 21st Century
2. Penn study shows an ancient crop effective in protecting against a 21st century hazard
3. Human influence on the 21st century climate: 1 possible future for the atmosphere
4. Illuminating life: How RNA, after a century in the shadows, emerged into the spotlight
5. Renaissance of 200-year old technology could ease 21st century sustainability challenges
6. Shrinking tundra, advancing forests: how the Arctic will look by centurys end
7. Captain Scotts century-old collections suggests marine life is capturing more carbon
8. More than 31 freshwater species have moved to Galicia over past century
9. A plan to promote sustainable US scientific discovery and innovation in the 21st century is proposed in OMICS
10. New study reveals decline of marine phytoplankton over the past century
11. Leaded gasoline predominant source of lead exposure in latter 20th century
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
21st century vaccines -- innovation in design and rational use
(Date:7/20/2017)... Delta (NYSE: DAL ) customers now can use ... Reagan Washington National Airport (DCA). ... Delta launches biometrics to board aircraft at Reagan Washington ... Delta,s biometric boarding pass experience that ... integrated into the boarding process to allow eligible Delta SkyMiles Members who ...
(Date:5/23/2017)... 2017  Hunova, the first robotic gym for the rehabilitation and functional ... in Genoa, Italy . The first 30 robots will ... USA . The technology was developed and patented at ... IIT spin-off Movendo Technology thanks to a 10 million euro investment from ... click: ...
(Date:4/24/2017)... , April 24, 2017 ... and partner with  Identity Strategy Partners, LLP (IdSP) ... "With or without President Trump,s March 6, 2017 ... Terrorist Entry , refugee vetting can be instilled with ... resettlement. (Right now, all refugee applications are suspended ...
Breaking Biology News(10 mins):
(Date:8/15/2017)... ... August 15, 2017 , ... Any expert in stem cell research or ... for more than half a century. Despite their essential roles in human health ... known that molecular tags developed for this purpose also tag other, more abundant, non-stem ...
(Date:8/14/2017)... Ca (PRWEB) , ... August 14, 2017 , ... ... poorly characterized and performing antibodies. Key researchers in the antibody community have recently ... characterization and consistency for antibodies in the laboratory. , The team ...
(Date:8/11/2017)... Calif. (PRWEB) , ... August 11, 2017 , ... Algenist ... plant collagen-based formulation unlocking collagen like never before. , Collagen is the key ... firsts to market with Liquid Collagen™, which include: , ...
(Date:8/10/2017)... ... 2017 , ... Each year in the United States more than 300,000 people ... independent lifestyle and, even worse, the one-year mortality rate is high, ranging from 12 ... of California Davis Medical Center (Sacramento) and Second Xiangya Hospital of the Central-South University ...
Breaking Biology Technology: