Navigation Links
2020 vision of vaccines for malaria, TB and HIV/AIDS
Date:5/25/2011

SEATTLE, WA, May 25, 2011 Collectively, malaria, TB & HIV/AIDS cause more than five million deaths per year nearly the entire population of the state of Washington and represent one of the world's major public health challenges as we move into the second decade of the 21st century. In the May 26, 2011, edition of the premier scientific journal Nature, Seattle BioMed Director Alan Aderem, Ph.D., along with Rino Rappuoli, Ph.D., Global Head of Vaccines Research for Novartis Vaccines & Diagnostics, discuss recent advances in vaccine development, along with new tools including systems biology and structure-based antigen design that could lead to a deeper understanding of mechanisms of protection. This, in turn, will illuminate the path to rational vaccine development to lift the burden of the world's most devastating infectious diseases.

According to Aderem, a systems biology pioneer who recently joined Seattle BioMed to incorporate that approach with the Institute's infectious disease research, new conceptional and technological advances indicate that it will be possible to develop vaccines for the "big three" infectious diseases within the next 10 years. "Success will be largely dependent on our ability to use novel approaches such as systems biology to analyze data sets generated during proof-of-concept trials," he explained. "This will lead to new insights such as the identification of correlates of protection or signatures of immunogenicity and the acceleration of large-scale clinical trials." Aderem added that innovative, new clinical and regulatory approaches will also accelerate the pathway to much-needed vaccines.

The article discusses the strengths and criticisms of the systems biology approach, with the key strength of the approach lying in its ability to capture and integrate massive amounts of biological data to visualize emergent properties that are not demonstrated by their individual parts and cannot be predicted from the
'/>"/>

Contact: Jennifer Mortensen
jennifer.mortensen@seattlebiomed.org
206-256-7220
Seattle Biomedical Research Institute
Source:Eurekalert

Page: 1 2

Related biology news :

1. LIAI launches new division to look at novel approaches to heart disease and inflammation
2. Rong Li Lab probes mechanism of asymmetry in meiotic cell division
3. Gene therapy restores vision to mice with retinal degeneration
4. New cell division mechanism discovered
5. The bonsai effect: Wounded plants make jasmonates, inhibiting cell division, stunting growth
6. NYU biologist Bonneau named among 20 "visionary" scientists under 40 by Discover magazine
7. Proteins strangle cell during division
8. Billion-year revision of plant evolution timeline may stem from discovery of lignin in seaweed
9. TECNALIA uses artificial vision to improve recycling of electronic scrap metal
10. Scientists deconstruct cell division
11. Cells with double vision
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/20/2015)... Conn. , May 20, 2015 NXT-ID, ... announces that its wholly owned subsidiary, 3D-ID LLC, a ... under Team Battelle for the biometrics technology portion of ... Suite Contract from the Department of the Army. ... recognition products developed for government, law enforcement and security ...
(Date:5/14/2015)... 14, 2015 Research and Markets ( ... "Fingerprint Sensors Market in Smart Mobile Devices " ... that 2014 was a watershed year for fingerprint sensors ... ,Apple Pay,. Apple gave fingerprint sensors a raison d,etre ... Fingerprint sensors are a must-have feature in flagship smartphones. ...
(Date:5/10/2015)... Fingerprint Cards (FPC) has received an order for ... World Peace Industrial Group (WPI), part of WPG Holdings. WPI ... . Deliveries are planned to take place during Q3 2015 ... China . The order value of 235 ... 1 000 MSEK for 2015.   Jörgen Lantto, acting ...
Breaking Biology News(10 mins):NXT-ID, Inc Announces Participation as Member of Team Battelle for TIES Contract Award 2NXT-ID, Inc Announces Participation as Member of Team Battelle for TIES Contract Award 3Global Smart Mobile Devices Fingerprint Sensors Market 2015-2019: Key Vendors are Authentec, Validity Sensors, Fingerprint Cards, Next Biometrics Group. IDEX, and Qualcomm 2Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 235 Million 2
... better understanding how antimicrobials bind and thereby get inactivated ... University of Illinois may have found a way to ... not a cure, this work has potential as a ... Gerard Wong a professor of materials science and engineering, ...
... nodes can be crucial for spreading low doses of ... as scrapie and Creutzfeldt-Jakob disease - into the nervous ... open access journal BMC Veterinary Research. While we can ... role in the neuroinvasion of prions for high doses ...
... caused the extinction of mammoths and the decline of ... debated. Overhunting by Paleoindians, climate change and disease lead ... considered a little out there is now hitting closer ... including two Northern Arizona University geologists, reports evidence that ...
Cached Biology News:Cystic fibrosis patients may breathe easier, thanks to bioengineered antimicrobials 2Lymph nodes can be key in spreading prion infectivity 2Research team says extraterrestrial impact to blame for Ice Age extinctions 2Research team says extraterrestrial impact to blame for Ice Age extinctions 3
(Date:5/21/2015)... VANCOUVER , May 21, 2015 /PRNewswire/ - ... a clinical stage regenerative medicine company focused on ... an upcoming poster presentation at the International Society ... treatment for chronic Achilles tendinosis currently in a ... on May 29 th from 5:30 PM ...
(Date:5/21/2015)... Tunnell Consulting, Inc. today ... senior statistician and Principal, a position to which she ... management and analysis of complex and large data sets ... “We’re delighted to have Julia join the Tunnell team ... Dr. Philippe Cini, Group Vice President and leader of ...
(Date:5/20/2015)... Research and Markets ( http://www.researchandmarkets.com/research/x4b7kw/top_technologies ) ... in HW_Technical Insights" report to their offering. ... trends in the Health and Wellness sector and has ... an impact in the year 2015. The research service ... health and wellness technologies that are anticipated to have ...
(Date:5/20/2015)... , May 19, 2015 Research and Markets ... the "Global Cell Therapy Market Outlook 2020 " ... cell therapy in tissue and regenerative medicine is expected ... other options which could help in the growth of ... segment but they are unable to form new tissue ...
Breaking Biology Technology:RepliCel to Present Unique Autologous Cell Treatment for Achilles Tendinosis at International Society for Cellular Therapy Conference 2RepliCel to Present Unique Autologous Cell Treatment for Achilles Tendinosis at International Society for Cellular Therapy Conference 3Julia O’Neill Joins Tunnell Consulting’s Operational and Process Improvement Practice 2Top Technologies in the Health and Wellness Industry 2015 2Global Cell Therapy Market Outlook 2015-2020 - 262 Cell Therapies & 13 Marketed Cell Therapies 2Global Cell Therapy Market Outlook 2015-2020 - 262 Cell Therapies & 13 Marketed Cell Therapies 3
... a movie about giant robots that undergo structural ... summer, a scientific study about structural transformations within ... design of novel materials that will serve next-generation ... Researchers at the U.S. Department of Energy (DOE),s ...
... most people, the clock changes just twice a year for ... (N24HWD, or Non-24), their internal body clock changes every ... is estimated that approximately 65,000 – 95,000 people suffer from ... can advance by about 15 minutes each night. Patients suffering ...
... 2011 Health Care Compliance Strategies, Inc. (HCCS) announced ... Care Nurses (AACN), to deliver a series of critical ... on HCCS Learning Management Systems.  This training includes two ... (ECCO) and Essentials of Nurse Manager Orientation ...
Cached Biology Technology:Nanocrystal transformers 2Nanocrystal transformers 3Nanocrystal transformers 4New Website Targets Common Sleep Disorder in Blind Individuals 2HCCS Partners with American Association of Critical Care Nurses (AACN) to Offer Nurse Training 2HCCS Partners with American Association of Critical Care Nurses (AACN) to Offer Nurse Training 3
Request Info...
Request Info...
Recombinant Rat Leptin, Ultra Pure...
Lentigen's manufacturing platform is sufficiently versatile for use in the manufacture of any HIV-based Lentiviral vector. Lentigen will manufacture your LV of choice to the highest possible titer a...
Biology Products: