Navigation Links
2020 vision of vaccines for malaria, TB and HIV/AIDS
Date:5/25/2011

SEATTLE, WA, May 25, 2011 Collectively, malaria, TB & HIV/AIDS cause more than five million deaths per year nearly the entire population of the state of Washington and represent one of the world's major public health challenges as we move into the second decade of the 21st century. In the May 26, 2011, edition of the premier scientific journal Nature, Seattle BioMed Director Alan Aderem, Ph.D., along with Rino Rappuoli, Ph.D., Global Head of Vaccines Research for Novartis Vaccines & Diagnostics, discuss recent advances in vaccine development, along with new tools including systems biology and structure-based antigen design that could lead to a deeper understanding of mechanisms of protection. This, in turn, will illuminate the path to rational vaccine development to lift the burden of the world's most devastating infectious diseases.

According to Aderem, a systems biology pioneer who recently joined Seattle BioMed to incorporate that approach with the Institute's infectious disease research, new conceptional and technological advances indicate that it will be possible to develop vaccines for the "big three" infectious diseases within the next 10 years. "Success will be largely dependent on our ability to use novel approaches such as systems biology to analyze data sets generated during proof-of-concept trials," he explained. "This will lead to new insights such as the identification of correlates of protection or signatures of immunogenicity and the acceleration of large-scale clinical trials." Aderem added that innovative, new clinical and regulatory approaches will also accelerate the pathway to much-needed vaccines.

The article discusses the strengths and criticisms of the systems biology approach, with the key strength of the approach lying in its ability to capture and integrate massive amounts of biological data to visualize emergent properties that are not demonstrated by their individual parts and cannot be predicted from the
'/>"/>

Contact: Jennifer Mortensen
jennifer.mortensen@seattlebiomed.org
206-256-7220
Seattle Biomedical Research Institute
Source:Eurekalert

Page: 1 2

Related biology news :

1. LIAI launches new division to look at novel approaches to heart disease and inflammation
2. Rong Li Lab probes mechanism of asymmetry in meiotic cell division
3. Gene therapy restores vision to mice with retinal degeneration
4. New cell division mechanism discovered
5. The bonsai effect: Wounded plants make jasmonates, inhibiting cell division, stunting growth
6. NYU biologist Bonneau named among 20 "visionary" scientists under 40 by Discover magazine
7. Proteins strangle cell during division
8. Billion-year revision of plant evolution timeline may stem from discovery of lignin in seaweed
9. TECNALIA uses artificial vision to improve recycling of electronic scrap metal
10. Scientists deconstruct cell division
11. Cells with double vision
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/15/2014)... an unexpected extent. The outbreak does not follow the ... a new disease dynamic in regions, where it has ... National Academy of Sciences Leopoldina, acatech – the German ... the German Academies of Sciences and Humanities have presented ... the statement the academies call for the following consequences ...
(Date:10/15/2014)... Oct. 15, 2014   Neurotechnology , a ... the availability of the VeriLook Surveillance 3.0 ... provides real-time biometric face identification using live video ... cameras. The new version not only identifies faces ... from objects while they are moving through the ...
(Date:10/14/2014)... fly genome for the first time, revealing robust immune ... thrives in pathogen-rich dung piles and garbage heaps. , ... Genome Biology , will increase understanding of house fly ... to resist insecticides, which could lead to novel control ... transmit more than 100 human and animal diseases, including ...
Breaking Biology News(10 mins):Academies call for consequences from the Ebola virus epidemic 2Academies call for consequences from the Ebola virus epidemic 3Academies call for consequences from the Ebola virus epidemic 4Academies call for consequences from the Ebola virus epidemic 5VeriLook Surveillance 3.0 SDK Identifies Faces and Moving Objects, Differentiates Pedestrians from Other Moving Objects in Video Surveillance Systems 2VeriLook Surveillance 3.0 SDK Identifies Faces and Moving Objects, Differentiates Pedestrians from Other Moving Objects in Video Surveillance Systems 3House fly genome reveals expanded immune system 2
... linked to many of the same health problems as tobacco ... wheeze, according to a new study by researchers at Yale ... used illicit drug in the United States, and abuse of ... in today's Archives of Internal Medicine. First author Jeanette M. ...
... of the same health problems as tobacco smoke, such as ... a new study by researchers at Yale School of Medicine. ... in the United States, and abuse of the drug is ... of Internal Medicine. First author Jeanette M. Tetrault, M.D., and ...
... has long been recognized that birds possess the ability to ... how this is done has not yet been clarified. ... homing pigeons in a new study (1) by Gerta Fleissner ... promising insight into this complex topic. The article will ...
Cached Biology News:Migration played key role in HIV spread in South Africa 2Long-term marijuana smoking leads to respiratory complaints 2Homing pigeons get their bearings from their beaks 2
(Date:10/22/2014)... HONG KONG , Oct. 22, 2014 /PRNewswire/ ... announced today that rare disease expert John C. ... research. Dr. McKew brings more than two decades of ... the National Institutes of Health, Wyeth Research and Genetics ... will lead aTyr,s efforts to expand and translate its ...
(Date:10/20/2014)... Texas (PRWEB) October 20, 2014 ... announced that a team from Iowa State University won ... design contest. Using a Convey HC-2ex, the team’s solution ... 14 times faster than the second place finisher. , ... world embarked upon the month long challenge, using a ...
(Date:10/20/2014)... 20, 2014 , A major ... and the delivery of care has revealed changing trends ... inequalities in the provision of healthcare services across the ... by United European Gastroenterology (UEG), have been announced today ... awareness of the burden of GI disorders across ...
(Date:10/20/2014)... 2014 OncLive® is ... Center at Thomas Jefferson University has joined its ... Strategic Alliance Partnership program, the Sidney Kimmel Cancer ... raise awareness of the Center’s cutting-edge research programs, ... Clinicians and other health care professionals from the ...
Breaking Biology Technology:aTyr Pharma Appoints John C. McKew, Ph.D., as Vice President, Research 2aTyr Pharma Appoints John C. McKew, Ph.D., as Vice President, Research 3Team from Iowa State Wins 2014 MemoCODE Design Contest Using Convey HC-2ex 2Team from Iowa State Wins 2014 MemoCODE Design Contest Using Convey HC-2ex 3Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 2Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 3Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 4Major Survey Reveals Changing Trends and Inequalities in Healthcare Provision for Gastrointestinal Disorders Across Europe 5Sidney Kimmel Cancer Center at Thomas Jefferson University Partners With OncLive 2Sidney Kimmel Cancer Center at Thomas Jefferson University Partners With OncLive 3
... Hospital and Medical Center and the University of Arizona College ... the Valley Fever Center based at the hospital.  The center ... than 30 years of experience in treating and researching Valley ... Tucson in 1996. The center plans to see ...
... MSC Care Management, the industry,s leading provider of ... workers, compensation claimants nationwide, announced today that it ... also focused on the workers, compensation industry, to ... management solution, known as S3. Integrated Healthcare Services, ...
... WEST LAFAYETTE, Ind., Oct. 4, 2011 Kylin ... today that it has received a notice of ... (USPTO) for its second U.S. patent application. This ... technology, as well as expanded areas on Kylin,s ...
Cached Biology Technology:St. Joseph's Hospital, University of Arizona Create Valley Fever Center in Phoenix 2MSC to Offer Surgical Implant Cost Management Solution through Acquisition of Integrated Healthcare Services 2Kylin Therapeutics Receives Notice of Allowance for Second U.S. Patent Covering Delivery of Therapeutic RNA and pRNAi Technology 2
ANTI PIG LDH H4...
... in refrigerators, freezers, or liquid nitrogen. Conveniently sized to ... color coding to project, user, lab, etc. Holes in ... air circulation. Supplied with 10 x 10 (11.6 mm ... dimensions: 13 x 13 x 5.1 cm H (5 ...
Recombinant Rhesus Monkey IFN-Alpha...
RABBIT ANTI AMPHOTERIN...
Biology Products: