Navigation Links
2 research facilities awarded technology seeding grants
Date:12/16/2011

The Ontario Genomics Institute (OGI) has awarded two research facilities with $10,000 each to test or develop leading-edge technologies to better aid the work of Ontario researchers.

The two recipients are The Centre for Applied Genomics (TCAG), part of The Hospital for Sick Children (SickKids) in Toronto and a Genome Canada Science and Technology Innovation Centre, and StemCore Laboratories based at the Ottawa Hospital Research Institute. Both technology seeding grants will benefit the advancement of Next Generation Sequencing (NGS) methods.

Dr. Stephen Scherer, Director of TCAG at SickKids and the University of Toronto's McLaughlin Centre, will be comparing methods that enable genome enrichment and exome capture. Exome sequencing, focused on sequencing the coding regions of the genome, has become a popular method for the identification of rare Mendelian genetic disorders using short-read, high-throughput NGS technologies. As the human exome comprises only about one to two percent of the whole genome, enough coverage can be obtained with less sequencing, hence reducing costs and having analysis completed in less time.

Dr. Scherer will examine two kits Illumina's TruSeq Exome Enrichment Kit and Life Tech TargetSeq Exome Enrichment kit. By evaluating the performance of both kits, the team will be able to provide better guidance to scientists in Ontario and further afield in choosing the most appropriate product and approach depending on the goals of each project and the amount of actual coverage and uniformity obtained for candidate genes.

The second recipient is Pearl Campbell at StemCore Labs who will be optimizing ChIP-Seq methods, which allows for clearer examination of protein interaction sites, important in understanding gene expression.

The team will undertake a systematic examination of the ChIP-Seq library construction protocol to optimize the amount of usable data that can be obtained from each experiment. Due to the limited number of publications dealing with optimization of ChIP-Seq library construction, it is hoped that this study may assist in the development of standard operating procedures and clarify best practices for bioinformatic handling of clonal duplications observed in SE ChIP-Seq data.

"Through our Technology Seeding grants, we are investing in revolutionary technologies that bring many benefits to the research community," commented Dr. Mark Poznansky, President and CEO, OGI. "Technology is key to genomics research and providing funding to test technologies and enable platforms to acquire leading technology is paramount to keep us at the leading edge of research."


'/>"/>

Contact: Alastair Harris-Cartwright
aharriscartwright@ontariogenomics.ca
416-673-6582
Ontario Genomics Institute
Source:Eurekalert

Related biology news :

1. Wistar Institute researcher receives New Innovator award from NIH
2. NC State researchers get to root of parasite genome
3. White Mountain Research Station to host climate change conference
4. Stevens awarded $1M for advanced biofuels research
5. Researchers find animal with ability to survive climate change
6. Researchers find an essential gene for forming ears of corn
7. Researchers note differences between people and animals on calorie restriction
8. Researcher working on destruction of chemical weapons
9. Researchers study acoustic communication in deep-sea fish
10. Researchers discover that growing up too fast may mean dying young in honey bees
11. The Rett Syndrome Research Trust launches operations
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/1/2016)... , Feb. 1, 2016  Wocket® smart wallet ( www.wocketwallet.com ) ... television personality, Joey Fatone . Las Vegas ... fans. --> Las Vegas , where Joey ... --> The new video ad was filmed at the Consumer Electronics ... at the Wocket booth to meet and greet fans. ...
(Date:1/22/2016)... , January 22, 2016 /PRNewswire/ ... announced the addition of the  "Global ... their offering. --> http://www.researchandmarkets.com/research/4lmf2s/global_behavioral ... the  "Global Behavioral Biometric Market 2016-2020" ... Research and Markets ( http://www.researchandmarkets.com/research/4lmf2s/global_behavioral ) ...
(Date:1/20/2016)... Jan. 20, 2016  Synaptics Incorporated (NASDAQ: ... solutions, today announced sampling of S1423, its newest ... and small screen applications including smartwatches, fitness trackers, ... round and rectangular shapes, as well as thick ... with moisture on screen, while wearing gloves, and ...
Breaking Biology News(10 mins):
(Date:2/8/2016)... ... February 08, 2016 , ... Bulk food ... bulk foods at various stages of the production process. Despite frequently inspecting loose ... bulk products post packaging such as sacks of dry powders. , Mettler-Toledo Product ...
(Date:2/8/2016)... -- NanoViricides, Inc. (NYSE MKT: NNVC) (the "Company"), a nanomedicine company developing ... MPH, will present information about the company,s programs at the BIOCEO ... New York City . --> ... 5:30PM EST. Registered attendees can request a one on one meeting ... --> New York City . ...
(Date:2/8/2016)... , Feb. 8, 2016  Diplomat Pharmacy, Inc. (NYSE: DPLO) announced today that its new website ... pharmacy resource–user-centric, story-driven, knowledge-based and mobile-friendly. Visit the ... ... ... "The goal was to ...
(Date:2/6/2016)... , ... February 06, 2016 , ... The Center for ... for middle and high school teachers on Wednesday February 10, 2016. This Bite ... the Smithsonian-Mason School of Conservation, located at 1500 Remount Road in Front Royal, VA ...
Breaking Biology Technology: