Navigation Links
2 research facilities awarded technology seeding grants
Date:12/16/2011

The Ontario Genomics Institute (OGI) has awarded two research facilities with $10,000 each to test or develop leading-edge technologies to better aid the work of Ontario researchers.

The two recipients are The Centre for Applied Genomics (TCAG), part of The Hospital for Sick Children (SickKids) in Toronto and a Genome Canada Science and Technology Innovation Centre, and StemCore Laboratories based at the Ottawa Hospital Research Institute. Both technology seeding grants will benefit the advancement of Next Generation Sequencing (NGS) methods.

Dr. Stephen Scherer, Director of TCAG at SickKids and the University of Toronto's McLaughlin Centre, will be comparing methods that enable genome enrichment and exome capture. Exome sequencing, focused on sequencing the coding regions of the genome, has become a popular method for the identification of rare Mendelian genetic disorders using short-read, high-throughput NGS technologies. As the human exome comprises only about one to two percent of the whole genome, enough coverage can be obtained with less sequencing, hence reducing costs and having analysis completed in less time.

Dr. Scherer will examine two kits Illumina's TruSeq Exome Enrichment Kit and Life Tech TargetSeq Exome Enrichment kit. By evaluating the performance of both kits, the team will be able to provide better guidance to scientists in Ontario and further afield in choosing the most appropriate product and approach depending on the goals of each project and the amount of actual coverage and uniformity obtained for candidate genes.

The second recipient is Pearl Campbell at StemCore Labs who will be optimizing ChIP-Seq methods, which allows for clearer examination of protein interaction sites, important in understanding gene expression.

The team will undertake a systematic examination of the ChIP-Seq library construction protocol to optimize the amount of usable data that can be obtained from each experiment. Due to the limited number of publications dealing with optimization of ChIP-Seq library construction, it is hoped that this study may assist in the development of standard operating procedures and clarify best practices for bioinformatic handling of clonal duplications observed in SE ChIP-Seq data.

"Through our Technology Seeding grants, we are investing in revolutionary technologies that bring many benefits to the research community," commented Dr. Mark Poznansky, President and CEO, OGI. "Technology is key to genomics research and providing funding to test technologies and enable platforms to acquire leading technology is paramount to keep us at the leading edge of research."


'/>"/>

Contact: Alastair Harris-Cartwright
aharriscartwright@ontariogenomics.ca
416-673-6582
Ontario Genomics Institute
Source:Eurekalert

Related biology news :

1. Wistar Institute researcher receives New Innovator award from NIH
2. NC State researchers get to root of parasite genome
3. White Mountain Research Station to host climate change conference
4. Stevens awarded $1M for advanced biofuels research
5. Researchers find animal with ability to survive climate change
6. Researchers find an essential gene for forming ears of corn
7. Researchers note differences between people and animals on calorie restriction
8. Researcher working on destruction of chemical weapons
9. Researchers study acoustic communication in deep-sea fish
10. Researchers discover that growing up too fast may mean dying young in honey bees
11. The Rett Syndrome Research Trust launches operations
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/14/2017)... , June 15, 2017  IBM (NYSE: IBM ) is ... tech event dedicated to developing collaboration between startups and global ... June 15-17. During the event, nine startups will showcase the ... in various industries. France ... international market, with a 30 percent increase in the number ...
(Date:5/16/2017)... 16, 2017   Bridge Patient Portal , ... MD EMR Systems , an electronic medical ... GE, have established a partnership to build an ... the GE Centricity™ products, including Centricity Practice Solution ... These new integrations will allow healthcare delivery ...
(Date:4/19/2017)... , April 19, 2017 ... its vendor landscape is marked by the presence of ... is however held by five major players - 3M ... these companies accounted for nearly 61% of the global ... leading companies in the global military biometrics market boast ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... Alto, CA, USA (PRWEB) , ... October 11, 2017 , ... ... set to take place on 7th and 8th June 2018 in San Francisco, CA. ... policy influencers as well as several distinguished CEOs, board directors and government officials from ...
(Date:10/11/2017)... , Oct. 11, 2017  VMS BioMarketing, a leading provider ... nationwide oncology Clinical Nurse Educator (CNE) network, which will launch ... for communication among health care professionals to enhance the patient ... office staff, and other health care professionals to help women ... cancer. ...
(Date:10/11/2017)... ... , ... Disappearing forests and increased emissions are the main causes of the ... Especially those living in larger cities are affected by air pollution related diseases. , ... pollution-affected countries globally - decided to take action. , “I knew I had to ...
(Date:10/11/2017)... Bay, Florida (PRWEB) , ... October 11, 2017 ... ... and Drug Administration (FDA) has granted orphan drug designation to SBT-100, its novel ... (sdAb) for the treatment of osteosarcoma. SBT-100 is able to cross the cell ...
Breaking Biology Technology: