Navigation Links
2 research facilities awarded technology seeding grants

The Ontario Genomics Institute (OGI) has awarded two research facilities with $10,000 each to test or develop leading-edge technologies to better aid the work of Ontario researchers.

The two recipients are The Centre for Applied Genomics (TCAG), part of The Hospital for Sick Children (SickKids) in Toronto and a Genome Canada Science and Technology Innovation Centre, and StemCore Laboratories based at the Ottawa Hospital Research Institute. Both technology seeding grants will benefit the advancement of Next Generation Sequencing (NGS) methods.

Dr. Stephen Scherer, Director of TCAG at SickKids and the University of Toronto's McLaughlin Centre, will be comparing methods that enable genome enrichment and exome capture. Exome sequencing, focused on sequencing the coding regions of the genome, has become a popular method for the identification of rare Mendelian genetic disorders using short-read, high-throughput NGS technologies. As the human exome comprises only about one to two percent of the whole genome, enough coverage can be obtained with less sequencing, hence reducing costs and having analysis completed in less time.

Dr. Scherer will examine two kits Illumina's TruSeq Exome Enrichment Kit and Life Tech TargetSeq Exome Enrichment kit. By evaluating the performance of both kits, the team will be able to provide better guidance to scientists in Ontario and further afield in choosing the most appropriate product and approach depending on the goals of each project and the amount of actual coverage and uniformity obtained for candidate genes.

The second recipient is Pearl Campbell at StemCore Labs who will be optimizing ChIP-Seq methods, which allows for clearer examination of protein interaction sites, important in understanding gene expression.

The team will undertake a systematic examination of the ChIP-Seq library construction protocol to optimize the amount of usable data that can be obtained from each experiment. Due to the limited number of publications dealing with optimization of ChIP-Seq library construction, it is hoped that this study may assist in the development of standard operating procedures and clarify best practices for bioinformatic handling of clonal duplications observed in SE ChIP-Seq data.

"Through our Technology Seeding grants, we are investing in revolutionary technologies that bring many benefits to the research community," commented Dr. Mark Poznansky, President and CEO, OGI. "Technology is key to genomics research and providing funding to test technologies and enable platforms to acquire leading technology is paramount to keep us at the leading edge of research."


Contact: Alastair Harris-Cartwright
Ontario Genomics Institute

Related biology news :

1. Wistar Institute researcher receives New Innovator award from NIH
2. NC State researchers get to root of parasite genome
3. White Mountain Research Station to host climate change conference
4. Stevens awarded $1M for advanced biofuels research
5. Researchers find animal with ability to survive climate change
6. Researchers find an essential gene for forming ears of corn
7. Researchers note differences between people and animals on calorie restriction
8. Researcher working on destruction of chemical weapons
9. Researchers study acoustic communication in deep-sea fish
10. Researchers discover that growing up too fast may mean dying young in honey bees
11. The Rett Syndrome Research Trust launches operations
Post Your Comments:
(Date:11/10/2015)... YORK , Nov. 10, 2015 ... to behavioral biometrics that helps to identify and ... fraud. Signature is considered as the secure and ... the identification of a particular individual because each ... more accurate results especially when dynamic signature of ...
(Date:11/2/2015)... , Nov. 2, 2015  SRI International has been ... provide preclinical development services to the National Cancer Institute ... will provide scientific expertise, modern testing and support facilities, ... preclinical pharmacology and toxicology studies to evaluate potential cancer ... The PREVENT Cancer Drug Development Program is an ...
(Date:10/29/2015)... , Oct. 29, 2015  Rubicon Genomics, Inc., ... U.S. distribution of its DNA library preparation products, ... Rubicon,s new ThruPLEX Plasma-seq kit. ThruPLEX Plasma-seq has ... preparation of NGS libraries for liquid biopsies--the analysis ... and prognostic applications in cancer and other conditions. ...
Breaking Biology News(10 mins):
(Date:11/25/2015)... -- 2 nouvelles études permettent d , ... entre les souches bactériennes retrouvées dans la plaque ... . Ces recherches  ouvrent une nouvelle voie ... efficace de l,un des problèmes de santé les ...    --> 2 nouvelles études permettent d ...
(Date:11/25/2015)... LOS ANGELES and HOLLISTON, Mass. ... Regenerative Technology, Inc. (Nasdaq: HART ), a biotechnology ... announced that CEO Jim McGorry will present ... Tuesday, December 1, 2015 at 2:30 p.m. PT. The ... (link below) for 30 days. Management will also be ...
(Date:11/25/2015)... 25, 2015 /PRNewswire/ - Aeterna Zentaris Inc. (NASDAQ:  AEZS; ... and prospects remain fundamentally strong and highlights the ... recently received DSMB recommendation to continue the ZoptEC ... of the final interim efficacy and safety data ... in men with heavily pretreated castration- and Taxane-resistant ...
(Date:11/25/2015)... Orexigen® Therapeutics, Inc. (Nasdaq: OREX ) ... chat discussion at the Piper Jaffray 27th Annual Healthcare ... discussion is scheduled for Wednesday, December 2, at 8:00 ... replay will be available for 14 days after the ... NormartVP, Corporate Communications and Business Development , BrewLife(858) 875-8629 ...
Breaking Biology Technology: