Navigation Links
2 neuroscientists from Cold Spring Harbor Laboratory awarded 'transformative' NIH grants
Date:9/24/2009

ogical and neuropsychiatric disorders."

The current proposal arose out of planning work in the Brain Architecture Project, undertaken by Mitra with initial funding from the W. M. Keck Foundation and involving important collaborations and contributions from Professor Larry Swanson of the University of Southern California and Jason Bohland, Ph.D., of CSHL, among others. Some of the early discussions took place at meetings Mitra organized over the last several years at CSHL's Banbury Center.

"We hope that the current project will be the seed for a larger community-wide effort for brain-wide circuit mapping across species, enabling comparative studies," said Mitra. "It is greatly encouraging that the NIH, in awarding this generous grant, has taken a leadership role in this area."

Dubnau: Tracing how brain proteins are regulated

Every neuron in the brain forms a complex web of fibers that make connections with countless other neurons. The brain must somehow maintain and control each of these connections by precisely regulating the synthesis or delivery of many different proteins to each of the neural connection points, called synapses. Geneticists already know a great deal about how cells control the quantity of each RNA synthesized ("transcribed") in the nucleus. But these RNA molecules each carry instructions beyond the nucleus, to direct the synthesis of a particular protein. Much less is known about how the translation of each RNA into a given protein is precisely controlled at each neuronal synapse.

Josh Dubnau's "transformative" project addresses an important gap in knowledge: about how this fundamental step in the conversion of genetic information -- its "translation" from RNA to protein -- is regulated in neurons, the ubiquitous cells of the brain whose dense web of connections underlie its capacity to perform sophisticated functions such as forming and storing memories.

"Every neuron in the bra
'/>"/>

Contact: Peter Tarr
tarr@cshl.edu
516-367-8455
Cold Spring Harbor Laboratory
Source:Eurekalert

Page: 1 2 3 4

Related biology news :

1. Caltech neuroscientists find brain region responsible for our sense of personal space
2. Neuroscientists discover long-term potentiation in the olfactory bulb
3. Bipolar disorder genes, pathways identified by Indiana University neuroscientists
4. Advertisers, neuroscientists trace source of emotions in brain
5. Early spring time for Edinburgh? Study predicts effect of global warming on spring flowers
6. Methods for gene transfer in stem cells featured in Cold Spring Harbor Protocols
7. Spring cold snap helps with stream ecosystem research
8. Springer to collaborate with the Human Genome Organization
9. Springer launches SpringerImages
10. Battle of the sexes benefits offspring, says research
11. Bisphenol A exposure in pregnant mice permanently changes DNA of offspring
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/31/2014)... synchrotron source that emits over a wide part of ... is currently being built in Lund, Sweden. The MAX ... the team putting together its component parts in a ... circumference of just a few hundred metres. Nevertheless, if ... new class of experiments that require source brightness and ...
(Date:10/31/2014)... Melbourne researchers have uncovered key steps involved in programmed ... diseases including lupus, cancers and neurodegenerative diseases. , ... Institute worked together to discover the three-dimensional structure of ... the first steps in how it causes cell death. ... and Proceedings of the National ...
(Date:10/30/2014)... a $1.04 million grant from the U.S. Army ... osteoarthritis using a patient,s own stem cells, spurred ... polymers., Liping Tang, a bioengineering professor and interim ... is primarily focused on helping soldiers who are ... if we inject microscaffolding that we,ve developed into ...
Breaking Biology News(10 mins):A new generation of storage -- ring 2A matter of life and death: Cell death proteins key to fighting disease 2UTA researcher uses microscaffolding injections to mend cartilage, prevent osteoarthritis 2
... Research(R), a revolutionary biometric media research firm specializing ... of Andre Marquis as Senior Vice President of ... for expanding Innerscope,s offering into the growing digital ... innovative digital initiatives for start-ups and Fortune 500 ...
... the world are building an extensive repository of genetically ... function of the approximately 57,000 genes that make up ... Genomics Consortium recently announced the public availability of more ... about half of the known functional genes mapped for ...
... 2009 Despite a down economy, Safeway Inc. presented ... at the Translational Genomics Research Institute (TGen). Dan ... stores throughout Arizona, thanked the grocery chain,s customers and ... very proud to donate to such an organization as ...
Cached Biology News:Innerscope Research(R) Appoints Digital Leader, Andre Marquis, as Senior Vice President of Sales and Marketing 2200,000 rice mutants available worldwide for scientific investigation 2Safeway gives $685,000 to TGen for breast cancer research 2
(Date:10/30/2014)... (PRWEB) October 30, 2014 The report ... Chemicals), by Application (Cosmetics & Toiletries, and Soaps & ... to 2019”, has defined and segmented the Fragrance Ingredients ... trends in terms of value. The market has been ... North America, Europe, Asia-Pacific, Latin America, and Rest of ...
(Date:10/30/2014)... 29, 2014 Global polyvinyl chloride (PVC) ... economic crisis during 2008-2009, especially in North America and ... currently is keeping to a growing trend. , The ... utilized in the construction segment. In 2013, the key ... tubing, sheets and rigid film. Moreover, the PVC was ...
(Date:10/30/2014)... (PRWEB) October 30, 2014 ... collaboration provider, offers Office 365 end users the ... a complete phone system by adding voice enablement ... (O365) includes Lync Online, a communication tool that ... calls. With hosted voice, O365 becomes a comprehensive ...
(Date:10/30/2014)... (PRWEB) October 30, 2014 Spartan Bioscience ... Spartan RX CYP2C19 System . It detects CYP2C19 genetic ... cheek swab. , The Spartan RX CYP2C19 System is ... has been approved in Canada. Due to the system’s ... may be used by healthcare professionals such as doctors, ...
Breaking Biology Technology:Fragrance Ingredients Market worth $17,104.21 Million by 2019 - New Report by MarketsandMarkets 2Fragrance Ingredients Market worth $17,104.21 Million by 2019 - New Report by MarketsandMarkets 3Fragrance Ingredients Market worth $17,104.21 Million by 2019 - New Report by MarketsandMarkets 4Fragrance Ingredients Market worth $17,104.21 Million by 2019 - New Report by MarketsandMarkets 5Global Polyvinyl Chloride Demand Is on Upward Trend Now, Says Merchant Research & Consulting in Its Topical Study 2Global Polyvinyl Chloride Demand Is on Upward Trend Now, Says Merchant Research & Consulting in Its Topical Study 3SoundConnect Launches Voice Enablement and Hybrid Audio Conferencing for Office 365 2SoundConnect Launches Voice Enablement and Hybrid Audio Conferencing for Office 365 3Health Canada approves first near-patient DNA test for personalized medicine 2Health Canada approves first near-patient DNA test for personalized medicine 3
... Optimal Microdissection , CapSure HS and CapSure ... rapid extraction of populations of pure cells ... Laser Capture Microdissection., Ensure the Integrity ... , All CapSure LCM Caps have a ...
... Precision-designed for Optimal Microdissection , ... enable the precise and rapid extraction of ... and cytology samples with Laser Capture Microdissection., ... for Downstream Molecular Analysis , All CapSure ...
... the method of choice for thousands of ... instrument to offer both LCM and Laser ... Laser Cutting provides unprecedented speed and ... large numbers of cells. , LCM ...
Bio-Plex Manager software, version 3.0, 5 license netshare, is a five-user software package that provides access to data from the Bio-Plex suspension array system from a server. This version does not...
Biology Products: