Navigation Links
2 UNC faculty receive Autism Centers of Excellence grants for new research
Date:9/4/2012

CHAPEL HILL, N.C. -- Two autism researchers in the University of North Carolina School of Medicine have each been awarded $12.6 million grants in the latest round of funding from the National Institutes of Health's Autism Centers of Excellence (ACE) research program.

UNC, which was ranked No. 2 among the top 25 institutions in the world publishing autism research in 2010 by the Interagency Autism Coordinating Committee, is one of only two institutions that have received more than one Autism Centers of Excellence grant.

"These grants are further evidence that UNC has become one of the premier autism research institutions in the world," said Dr. Joseph Piven, recipient of a grant for a new round of research in the ongoing Infant Brain Imaging Study (IBIS) Network.

The NIH created the Ace Program in 2007 to launch an intense and coordinated research program into the causes of autism spectrum disorders (ASD) and to find new treatments.

The grant to Dr. Piven, Kenan Professor of Psychiatry and Director of the Carolina Institute for Developmental Disabilities, will be used to fund longitudinal brain imaging of a combined sample of 600 infants who are at high risk for later developing autism by virtue of having an older sibling with autism. The Infant Brain Imaging Network, or IBIS, which is led by UNC and includes clinical study sites at Children's Hospital of Philadelphia, the University of Washington in Seattle and Washington University in St. Louis, will conduct the study.

"The identification of early brain markers in infants who later develop autism, during a period when children may benefit maximally from early detection and intervention, has the potential to significantly improve the lives of autistic individuals," Piven said.

Dr. Linmarie Sikich, associate professor of psychiatry and director of the Adolescent and School-age Psychiatric Intervention REsearch Program (ASPIRE), has been awarded a $12.6 million grant to establish a new research network, the ACE SOARS Network , to develop and test new treatments for autism spectrum disorders (ASD). Dr. Sikich will direct the ACE SOARS Network and provide overall project coordination.

The first project the ACE SOARS network will undertake is a 5-year study of oxytocin nasal spray in children and adolescents (ages 3-17) with an autism spectrum disorder called SOARS-B (Study of Oxytocin in Autism to improve Reciprocal Social Behaviors), which will be conducted at treatment centers at UNC, Harvard University, Mount Sinai School of Medicine, Vanderbilt University and University of Washington with genetic analyses done at Duke University. The SOARS-B study will determine if oxytocin improves social functioning in ASD, evaluate oxytocin's safety in children, and identify factors that influence a child's response to oxytocin. The study is the largest treatment study to date and will ultimately include 300 individuals with an autism spectrum diagnosis. It is also one of the first studies that will focus equally on both verbal and nonverbal individuals on the spectrum.

"We are very grateful for our government's support of autism research and are excited to be a part of efforts to develop safe and effective treatments to improve the core symptoms of autism," Sikich said. "At least 1.5 million Americans suffer from autism, but options for treatment are currently limited."

"Our SOARS-B study is a great example of translational science to develop new treatments," Sikich said. "A large clinical trial is needed to really figure out whether oxytocin works in autism and is only possible with the support of the National Institutes of Health and the cooperation of medical centers across the country since no U.S. pharmaceutical companies are currently marketing intranasal oxytocin."

Dr. Piven said that UNC research on autism "covers that gamut from basic neurobiology to clinical research on pathogenesis to applied research on intervention.

"The breath of the IBIS and ACE SOARS research networks, one focusing on brain development in infants at risk for autism and the other conducting research on a novel therapeutic intervention for autism, are examples of the depth and range of autism research at UNC," he said.

The ACE research program is funded by five NIH institutes: the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), the National Institute on Deafness and Other Communication Disorders, the National Institute of Environmental Health Sciences, the National Institute of Mental Health and the National Institute of Neurological Disorders and Stroke.


'/>"/>

Contact: Tom Hughes
tahughes@unch.unc.edu
919-966-6047
University of North Carolina Health Care
Source:Eurekalert  

Related biology news :

1. IU biologist receives Department of Energys top young faculty award
2. In search for a vaccine, IU biologist receives $2.3 million to explore chlamydia genomics
3. WHOI researchers, collaborators receive $1.4 million grant to study life in oceans greatest depths
4. Renowned geneticist R. Rodney Howell receives ACMG Foundation Lifetime Achievement Award
5. UF receives $1 million from Keck Foundation to study mechanisms of inherited disease
6. Gladstone scientist Warner C. Greene receives Washington University School of Medicine Alumni Award
7. Carnegies Wolf B. Frommer receives Bogorad Award for Excellence in Plant Biology
8. UC Riverside plant cell biologist receives top scientific honor
9. UC Riverside receives grant for global health and development research
10. Washington University receives $8 million to lead international childhood malnutrition effort
11. SRI Sarnoffs Iris on the MoveĀ® N-Glanceā„¢ Identification System Receives Lenel Factory Certification
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
2 UNC faculty receive Autism Centers of Excellence grants for new research
(Date:11/22/2016)... 22, 2016 According to the new market research ... Face, Vein, Signature, Voice), Multi-Factor), Component (Hardware and Software), Function (Contact and ... the market is expected to grow from USD 10.74 Billion in 2015 ... between 2016 and 2022. Continue Reading ... ...
(Date:11/21/2016)... 21, 2016   Neurotechnology , a provider ... today announced that the MegaMatcher On Card fingerprint ... for the NIST Minutiae Interoperability Exchange (MINEX) ... mandatory steps of the evaluation protocol. ... test of fingerprint templates used to establish compliance ...
(Date:11/17/2016)... , Nov. 17, 2016 Global Market Watch: ... Biobanks (Disease-Based Banks, Population-Based Banks and Academics) market is to ... for Private Biobanks shows the highest Compounded Annual Growth Rate ... region during the analysis period 2014-2020. North ... of 9.95% followed by Europe at ...
Breaking Biology News(10 mins):
(Date:12/7/2016)... ... December 07, 2016 , ... ... and online shopping cart. The new website has been designed to provide ... digital components allow customers to access detailed product information, read educational industry content ...
(Date:12/7/2016)... Hole, Massachusetts (PRWEB) , ... December 07, 2016 , ... Kara Dwyer Dodge grew up ... Richard Dwyer, a third-generation fisherman in Scituate, Mass., found a sea turtle entangled in the ... shore, where the turtle became a minor sensation because no one could remember ever seeing ...
(Date:12/6/2016)... Diagnostics Inc. ("SQI" or the "Company") (TSX-V: SQD; OTCQX: SQIDF), today reported ... year ended September 30, 2016. ... , , SQI is ... that develops and commercializes proprietary technologies and products for advanced multiplexed ... of $1.4 million more than tripling prior years revenue. ...
(Date:12/6/2016)... ... 06, 2016 , ... The Osteoarthritis Research Society International (OARSI) ... (FDA) to consider OA as a serious disease. As an organization of professionals ... of OA patients, many of whom may experience progressive disability and decreased quality ...
Breaking Biology Technology: