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$7.5M grant to fund research on interaction of drinking and HIV infection
Date:10/20/2010

al, will study changes in the brain structure, metabolism, and cognitive functioning of heavier and lighter drinkers with HIV over three years.

In another study at Fenway Health in Boston led by Christopher Kahler, professor of community health (research) and scientific director of the ARCH, and Kenneth Mayer, professor of medicine based at The Miriam, Monti will adapt an effective emergency room alcohol intervention he has developed for a clinical trial with chronic heavy drinkers with HIV. The "motivational interview" technique presents facts and feedback about a patient's consumption compared to that of peers and relays information about the health effects of the patient's level of drinking.

"You don't hammer patients over the head with it, but you present them with the information in a nonconfrontational style and ask them what they think about it," Monti said. "You ask them whether they'd be interested in changing and if the answer is yes, you give them some thumbnail sketches about how they might want to go about that."

In another new but separate $4-million grant, Monti will develop and test an emergency room intervention method to curb sexual risk-taking and heavy alcohol consumption.

The ARCH pilot studies will investigate the role of occult hepatitis C in the HIV and alcohol mix, the effects of HIV and drinking during pregnancy on newborns, the brain response that HIV-positive drinkers have to various stimuli depending on their level of use and acute brain response to alcohol, and the effects of drinking and HIV among fishermen and commercial sex workers in Uganda. Additional pilot studies will be jointly funded by the ARCH and Brown's Center for AIDS Research, directed by Charles Carpenter, professor of medicine based at The Miriam.

Another major element of the program, led by Mayer and Suzanne Colby, associate professor of psychiatry and human behavior (research), will be to educate postdoctoral trainees and d
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Contact: David Orenstein
david_orenstein@brown.edu
401-863-1862
Brown University
Source:Eurekalert

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