Navigation Links
$3.75 million grant advances tissue engineering partnership
Date:1/27/2010

aterials, TECs exhibit promise as a treatment after tendon injury. By mechanically stimulating TECs prior to surgery, Butler says UC researchers have created TECs that almost exactly match the functional stiffness of the normal tendon. But, he says, these TEC-based repairs can't completely recreate the exact tendon architecture, especially where it inserts into bone.

That led to the partnership between Butler's lab and the lab of Christopher Wylie, PhD, professor and director of the division of developmental biology at CCHMC.

"We want to understand how the tendon normally develops," says Butler, "because we might then be able to introduce or precondition these TECs biologically in a way that's even more effective than what we've done using mechanical stimulation. We actually hope to introduce some of these signals that we measure during growth and development during the repair process that occurs after injury in the adult tendon."

Using multi-functional tissue engineering, Butler and Wylie will identify which genes and signaling pathways are expressed at different stages of normal tendon development.

Then, they will work to experimentally manipulate the expression of those target genes and signals in TECs prior to introducing them at surgery.

They hope that the research will not only lead to better TECs for soft tissue repair, but a maturation of tissue engineering principles that can be applied for bone or cartilage repair.

In order to share those principles, Butler and Wylie will present their work to a consortium of clinical and basic science investigators as well as an industry panel at a one-day conference at UC in April.

"These BRPs are not about just doing fundamental research," Butler says, "they're about translating that research to more rapidly bring treatments to patients."


'/>"/>

Contact: Katy Cosse
kathryn.cosse@uc.edu
513-558-0207
University of Cincinnati Academic Health Center
Source:Eurekalert

Page: 1 2

Related biology news :

1. T. Denny Sanford donates $50 million to Burnham Institute for Medical Research
2. Duke awarded up to $43 million to develop test for dirty bomb/radiation exposure
3. UF gets almost $15 million in federal funds to build research complex to help older adults
4. Molecular Biometrics Closes $12.5 Million Series B Equity Funding
5. $1 million from NIH continues cell growth regulation studies
6. Brandeis wins $1 million Keck Foundation grant to research active matter
7. LSUHSC awarded multi-million dollar grant to reduce pneumonia
8. University of Maryland School of Medicine receives $30 million to coordinate stem cell consortium
9. Story of 4.5 million-year-old whale unveiled in Huelva
10. NTU and EDB launch S$50 million ($36 million) integrated circuit design research center
11. Penn, Georgia collaboration awarded $14.6 million to expand pathogen database
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/31/2015)...   Guidepoint , a leading global research services ... Management TRACKER, part of the Guidepoint TRACKER ... medical device and therapeutics markets. The Post-Surgical Pain Management ... market share, and adoption rates across three major modalities ... The Post-Surgical Pain Management TRACKER will provide ...
(Date:3/24/2015)... and Markets ( http://www.researchandmarkets.com/research/hdgz7h/global_iris ) has announced ... 2015-2019" report to their offering. The ... at a CAGR of 23.5 percent over the period ... and the growth prospects of the Global Iris Recognition ... size, the report considers the revenue generated from sales ...
(Date:3/24/2015)... , March 24, 2015   Crossmatch ™, ... today announced that its U.are.U ® 4500 ... Goorin Bros . to achieve PCI compliance ... secures access to the POS terminal, protecting the ... of data breaches. With one-third ...
Breaking Biology News(10 mins):Guidepoint Launches Post-Surgical Pain Management TRACKER 2Guidepoint Launches Post-Surgical Pain Management TRACKER 3Global Iris Recognition Market 2015-2019 with 3M Cogent, Bioenable Technologies, Cross Match Technology, Iris ID Systems & Safran Dominating 2Crossmatch Fingerprint Readers Help Retailer Prevent Data Breaches at Point-of-Sale 2
... occur in sports and in combat, but health experts ... head movements during these activities pose the greatest risks ... have developed a powerful new computer-based process that helps ... injuries. This approach could lead to new medical treatment ...
... 12, 2013The foodborne bacteria Listeria monocytogenes sickens ... many more worldwide, killing about 25-30% of those infected. ... L. monocytogenes , and current methods for detecting the ... method for developing an inexpensive biosensor to detect the ...
... maxillary sinuses. Those bulbous pouches on either side of the ... sinus infections than anything else. They were thought to be ... present value. Yet researchers led by the University of ... role in the shape and function of the human nose, ...
Cached Biology News:Computer model may help athletes and soldiers avoid brain damage and concussions 2Computer model may help athletes and soldiers avoid brain damage and concussions 3Low-cost nano-biosensor to detect foodborne pathogen that causes listeriosis 2Low-cost nano-biosensor to detect foodborne pathogen that causes listeriosis 3The nose's unheralded neighbor 2The nose's unheralded neighbor 3
(Date:5/1/2015)... MN , May 1, 2015 /PRNewswire/ - BioAmber ... producing sustainable chemicals, today announced that it has priced an ... stock at a price of $9.00 per share, and ... to purchase up to an additional 585,000 shares of ... will be $35.1 million.  The offering is expected to close ...
(Date:5/1/2015)... , May 1, 2015 ... Genetic Technologies Ltd (NASDAQ: GENE ), Agilent ... Scientific Inc. (NYSE: TMO ), Sequenom Inc. ... PKI ). Free research report on Genetic ... On Thursday, April 30, 2015, the NASDAQ Composite ...
(Date:4/30/2015)... Blythewood, South Carolina (PRWEB) May 01, 2015 ... steam system services, is extremely proud to announce that ... have been named as a winner of a Queen’s ... business success for the design and manufacture of a ... is the revolutionary alternative to traditional steam flow ...
(Date:4/30/2015)... - BioAmber Inc. (NYSE: BIOA ), an industrial ... commenced an underwritten public offering of its common stock.  ... 30-day option to purchase up to an additional 15 ... the public offering. The offering is subject to market ... whether or when the offering may be completed, or ...
Breaking Biology Technology:BioAmber Inc. Announces Pricing Of $35.1 Million Registered Offering 2BioAmber Inc. Announces Pricing Of $35.1 Million Registered Offering 3Life Sciences Tools and Services Stocks on our Radar -- Genetic Technologies, Agilent Technologies, Thermo Fisher Scientific, Sequenom, and PerkinElmer 2Life Sciences Tools and Services Stocks on our Radar -- Genetic Technologies, Agilent Technologies, Thermo Fisher Scientific, Sequenom, and PerkinElmer 3Life Sciences Tools and Services Stocks on our Radar -- Genetic Technologies, Agilent Technologies, Thermo Fisher Scientific, Sequenom, and PerkinElmer 4Life Sciences Tools and Services Stocks on our Radar -- Genetic Technologies, Agilent Technologies, Thermo Fisher Scientific, Sequenom, and PerkinElmer 5Spirax Sarco Receives a Queen’s Award for Innovation 2Spirax Sarco Receives a Queen’s Award for Innovation 3BioAmber Inc. Announces Public Offering Of Common Stock 2BioAmber Inc. Announces Public Offering Of Common Stock 3
... Multiple Fields, Strengthening the Molecular Bioassays Market , ... Based on its recent analysis of the molecular ... with the 2009 Frost & Sullivan North America ... pioneering Tag-lite(TM) technology for cell surface receptor investigation, ...
... , PHILADELPHIA and LONDON, June 9 /PRNewswire/ -- ... reported today that, despite difficult economic times, renewals of ... many existing customers have even added new content to ... is the world,s largest citation database, providing researchers, administrators, ...
... Executive to Lead Personalized Medicine Company in Next Phase of Growth ... , a personalized medicine company, announced today ... new President and CEO. , , Burns comes to ... strategic management of science and technology for pharmaceutical, diagnostic, and biotech ...
Cached Biology Technology:Frost & Sullivan Recognizes Cisbio Bioassays for Technology Innovation 2Frost & Sullivan Recognizes Cisbio Bioassays for Technology Innovation 3Frost & Sullivan Recognizes Cisbio Bioassays for Technology Innovation 4Frost & Sullivan Recognizes Cisbio Bioassays for Technology Innovation 5Web of Science(R) Renewals Remain Strong Despite Tough Economic Climate 2AssureRx Adds New CEO 2