Navigation Links
$12 million for a center for research on aphasia
Date:3/26/2013

EVANSTON, Ill. --- Northwestern University has received a $12 million grant from the National Institutes of Health (NIH) to establish a center devoted to research on aphasia, a devastating language disorder that essentially robs the brain of language.

"In the U.S. alone, more than one million people suffer from aphasia, rendering normal communication impossible," said Cynthia Thompson, who will direct the new Center for the Neurobiology of Language Recovery. "For the first time, the best researchers in the field will work together to find biomarkers that can predict language recovery."

A world-renowned researcher on aphasia, brain plasticity and language recovery, Thompson is the primary investigator of the prestigious NIH Center grant and the Jean and Ralph Sundin Professor of Communication Sciences.

The center will bring Thompson and top aphasia researchers from Johns Hopkins, Harvard and Boston universities together to do large-scale investigations that shed light on how language is processed in healthy people and how language recovers when impaired by stroke or other neurological disease processes.

Research conducted through the new center will have the potential to challenge existing clinical practices for aphasia and promote the availability of treatment for individuals with chronic aphasia. Health insurance policies today typically restrict treatment to only a few sessions immediately after the onset of stroke.

The work of the center is expected to significantly impact clinical intervention practices for individuals with aphasia as well as expand knowledge about brain plasticity and the reorganization of language functions. The center, which will study more than 200 patients, also will generate a large database for other researchers to access.

At Northwestern, Thompson will continue her focus on agrammatic aphasia, a form of aphasia that affects the ability to understand and produce sentences. At Harvard and Boston, researchers David Caplan and Swathi Kiran will study anomic aphasia, a form of aphasia that affects processing of spoken words. And at Johns Hopkins, Brenda Rapp will conduct research on the neurobiology of the recovery of spelling (writing) processes.

In groundbreaking research, Thompson has shown that the brain has the capacity to recover many years following stroke as opposed to only in the first few months after stroke's onset. She also has demonstrated that behavioral treatment of aphasia focused on improving impaired language processing affects not only the ability to understand and produce language but also activity in the brain.

"Right now we know little about the factors that affect language recovery, although our recent work examining blood flow in the brain holds promise," Thompson said. In a landmark 2010 study, she and her team discovered that measures of blood flow can aid in predicting language recovery following stroke.

Researchers will study blood flow and other potential biomarkers of recovery, including brain activity during the "resting state." Using functional magnetic resonance imaging (fMRI), they also will study the integrity of white matter tracts (the fibers that connect brain regions with one another) and whether damage to these tracts influences language recovery.

Across projects, the researchers will gather behavioral and neuroimaging data using a common, comprehensive battery of measures. They will include fMRI, structural and perfusion imaging and diffusion tensor imaging as tools for identifying, monitoring and evaluating areas of the brain associated with language recovery.

In more exploratory research, researchers will use eye tracking to study cognitive strategies used by healthy and brain damaged people while they process language. Researchers will track the eye movement patterns of healthy people, compare those patterns to those of people with aphasia, and study how, or if, eye movements normalize with recovery.


'/>"/>

Contact: Wendy Leopold
w-leopold@northwestern.edu
847-491-4890
Northwestern University
Source:Eurekalert

Related biology news :

1. Oceans acidifying faster today than in past 300 million years
2. Autism Speaks awards $1.1 million to fund high priority studies
3. In search for a vaccine, IU biologist receives $2.3 million to explore chlamydia genomics
4. WHOI researchers, collaborators receive $1.4 million grant to study life in oceans greatest depths
5. University leads £6 million EU project to tackle obesity
6. Scientists win $2 million to study new pathway in development and maintenance of lymphoma
7. 17th century Dutch explorers help the Atlas reach a major milestone -- 30 million records
8. Mafic melts, methane seeps, 2 million waves, foreign magma, and the invisible hand
9. UF receives $1 million from Keck Foundation to study mechanisms of inherited disease
10. Scientist wins $3 million renewal of one of longest-running NIH grants to Scripps Research
11. From 503-million-year-old fungi to recent earthquakes: New Geology posted ahead of print
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/28/2017)... , March 28, 2017 The ... Hardware (Camera, Monitors, Servers, Storage Devices), Software (Video Analytics, ... Region - Global Forecast to 2022", published by MarketsandMarkets, ... 2016 and is projected to reach USD 75.64 Billion ... and 2022. The base year considered for the study ...
(Date:3/24/2017)... 24, 2017 The Controller General of Immigration from ... Abdulla Algeen have received the prestigious international IAIR Award for the ... Continue Reading ... ... Controller Abdulla Algeen (small picture on the right) have received the IAIR ...
(Date:3/23/2017)... The report "Gesture Recognition and Touchless Sensing Market by Technology (Touch-based ... to 2022", published by MarketsandMarkets, the market is expected to be worth USD ... 2022. Continue Reading ... ... ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... and LAGUNA HILLS, Calif. , Oct. ... Cancer Research, London (ICR) and University ... SKY92, SkylineDx,s prognostic tool to risk-stratify patients with multiple myeloma ... MUK nine . The University of Leeds ... partly funded by Myeloma UK, and ICR will perform the ...
(Date:10/10/2017)... ... 2017 , ... San Diego-based team building and cooking events company, Lajollacooks4u, has ... The bold new look is part of a transformation to increase awareness, appeal to ... period. , It will also expand its service offering from its signature gourmet cooking ...
(Date:10/10/2017)... 10, 2017 International research firm Parks Associates announced ... at the TMA 2017 Annual Meeting , October 11 in ... residential home security market and how smart safety and security products impact ... Parks Associates: Smart Home ... "The residential security market has ...
(Date:10/9/2017)... DIEGO , Oct. 9, 2017  BioTech ... biological mechanism by which its ProCell stem cell ... critical limb ischemia.  The Company, demonstrated that treatment ... amount of limbs saved as compared to standard ... the molecule HGF resulted in reduction of therapeutic ...
Breaking Biology Technology: