Navigation Links
$1 million from NIH continues cell growth regulation studies
Date:1/11/2010

MELBOURNE, FLA. The new year began on a high note for Alan Leonard and Julia Grimwade, professors of biological sciences at Florida Institute of Technology, when they learned their National Institutes of Health grant, which they have held for the last 11 years, had been renewed for four more years. The competitive renewal brings them $1,024, 944 to continue their research into the regulation of cell growth and division.

The reproduction of cells from all types of organisms, from bacteria to humans, is tightly regulated to ensure that cells grow and divide only when it is appropriate for them to do so. When the regulation fails, diseases such as cancer can arise.

"We study how cellular proteins and DNA join together to form a very small molecular machine that acts as an 'on' switch, telling cells that it is time to begin a new replication cycle," said Leonard. "Because bacteria have far fewer protein and DNA components acting as cell growth regulators than mammalian cells do, we use the rapidly growing human gut bacterium, Escherichia coli, as a model system. However, the studies should shed light on cell growth regulation in all organisms."

The researchers hope to use the information they collect about how the switch is assembled to develop inhibitors that would prevent the cellular components from coming together. Such inhibitors could be the precursors to novel antibiotics that would fight bacterial diseases that are resistant to existing therapies, or could even be used to discover new drugs to treat cancer.

The funding will create several new jobs for technical support personnel, as well as provide support for doctoral students who are completing their training in the lab.


'/>"/>

Contact: Karen Rhine
krhine@fit.edu
321-674-8964
Florida Institute of Technology
Source:Eurekalert

Page: 1

Related biology news :

1. Brandeis wins $1 million Keck Foundation grant to research active matter
2. LSUHSC awarded multi-million dollar grant to reduce pneumonia
3. University of Maryland School of Medicine receives $30 million to coordinate stem cell consortium
4. Story of 4.5 million-year-old whale unveiled in Huelva
5. NTU and EDB launch S$50 million ($36 million) integrated circuit design research center
6. Penn, Georgia collaboration awarded $14.6 million to expand pathogen database
7. Abundance of a look-alike species clouds population status of a million dollar fish
8. $2.4 million stimulus fuels effort to regenerate injured spinal cords
9. NIH awards $8.5 million for research on pharmaceuticals for children
10. ASU research efforts to improve human health will get $3 million in federal stimulus grants
11. Study pits man v. machine in piecing together 425-million-year-old jigsaw
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/5/2017)... 5, 2017 Today HYPR Corp. , ... server component of the HYPR platform is officially ... end-to-end security architecture that empowers biometric authentication across Fortune ... already secured over 15 million users across the financial ... connected home product suites and physical access represent a ...
(Date:4/3/2017)... WASHINGTON , April 3, 2017 /PRNewswire-USNewswire/ ... single-cell precision engineering platform, detected a statistically ... cell product prior to treatment and objective ... highlight the potential to predict whether cancer ... prior to treatment, as well as to ...
(Date:3/30/2017)... 2017 Trends, opportunities and forecast in this ... technology (fingerprint, AFIS, iris recognition, facial recognition, hand geometry, ... end use industry (government and law enforcement, commercial and ... and others), and by region ( North America ... Asia Pacific , and the Rest of the ...
Breaking Biology News(10 mins):
(Date:4/20/2017)... ... April 20, 2017 , ... Parallel6™ , the leader in ... today that they were named one of the 2017 Top 10 eClinical Trial ... in the pharmaceutical industry. , “We take pride in honoring Parallel6 as one of ...
(Date:4/20/2017)... N.J. and PETACH TIKVAH, Israel ... BCLI), a leading developer of adult stem cell technologies for ... Executive Officer, will present at the Alliance for Regenerative Medicine,s ... Day on Thursday, April 27, 2017 at 09:40 EDT in ... Ralph Kern , MD, MHSc, Chief Medical Officer & ...
(Date:4/19/2017)... ... ... A number of new instruments have recently emerged to accommodate different applications ... and Cell Analysis Education Webinar Series , will focus on advances in the Invitrogen™ ... applications. , Many flow cytometers have unique capabilities and the Attune NxT Flow ...
(Date:4/19/2017)... ... April 19, 2017 , ... Nobilis Therapeutics Announces Completion ... to Leverage Clinical Data in its Upcoming Post Traumatic Stress Disorder Trial , ... patient clinical trial assessing efficacy of its NBTX-001, a xenon-based therapeutic in the treatment ...
Breaking Biology Technology: