Navigation Links
$1 million from NIH continues cell growth regulation studies
Date:1/11/2010

MELBOURNE, FLA. The new year began on a high note for Alan Leonard and Julia Grimwade, professors of biological sciences at Florida Institute of Technology, when they learned their National Institutes of Health grant, which they have held for the last 11 years, had been renewed for four more years. The competitive renewal brings them $1,024, 944 to continue their research into the regulation of cell growth and division.

The reproduction of cells from all types of organisms, from bacteria to humans, is tightly regulated to ensure that cells grow and divide only when it is appropriate for them to do so. When the regulation fails, diseases such as cancer can arise.

"We study how cellular proteins and DNA join together to form a very small molecular machine that acts as an 'on' switch, telling cells that it is time to begin a new replication cycle," said Leonard. "Because bacteria have far fewer protein and DNA components acting as cell growth regulators than mammalian cells do, we use the rapidly growing human gut bacterium, Escherichia coli, as a model system. However, the studies should shed light on cell growth regulation in all organisms."

The researchers hope to use the information they collect about how the switch is assembled to develop inhibitors that would prevent the cellular components from coming together. Such inhibitors could be the precursors to novel antibiotics that would fight bacterial diseases that are resistant to existing therapies, or could even be used to discover new drugs to treat cancer.

The funding will create several new jobs for technical support personnel, as well as provide support for doctoral students who are completing their training in the lab.


'/>"/>

Contact: Karen Rhine
krhine@fit.edu
321-674-8964
Florida Institute of Technology
Source:Eurekalert

Page: 1

Related biology news :

1. Brandeis wins $1 million Keck Foundation grant to research active matter
2. LSUHSC awarded multi-million dollar grant to reduce pneumonia
3. University of Maryland School of Medicine receives $30 million to coordinate stem cell consortium
4. Story of 4.5 million-year-old whale unveiled in Huelva
5. NTU and EDB launch S$50 million ($36 million) integrated circuit design research center
6. Penn, Georgia collaboration awarded $14.6 million to expand pathogen database
7. Abundance of a look-alike species clouds population status of a million dollar fish
8. $2.4 million stimulus fuels effort to regenerate injured spinal cords
9. NIH awards $8.5 million for research on pharmaceuticals for children
10. ASU research efforts to improve human health will get $3 million in federal stimulus grants
11. Study pits man v. machine in piecing together 425-million-year-old jigsaw
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2014)... Canada has issued a high health risk warning for ... the region due to forest fires. In the ... drifting eastward along normal wind patterns. Fire is ... from fires is not quite so obvious and its ... type of fire (forest, brush, crop, structure, tires, waste ...
(Date:7/23/2014)... that has the entire country in its grip is affecting ... be responsible for the proliferation of a heat-loving amoeba commonly ... hot springs, which the drought has made warmer than usual ... an infection caused by this parasite after swimming in several ... of an individual and travels to the brain. Nose plugs ...
(Date:7/23/2014)... This news release is available in German . ... shape and stability to cells, drive metabolic processes and ... into complex three-dimensional shapes. Scientists at the Max Planck ... that proteins can be constructed of similar amino acid ... suggests that the proteins that exist today arose from ...
Breaking Biology News(10 mins):Diseases of another kind 2Protein evolution follows a modular principle 2
... to harness DNA,s powerful molecular machinery to build artificial ... pairs of DNA molecules to assemble into complex structures. ... of Technology,* could provide a means of assembling complex ... systems, from the bottom up. While most researchers ...
... This release is available in German . ... supports the sperm in their quest by emitting attractants. Calcium ions ... sperm to move. Together with colleagues from the Max Planck Institute ... of Gttingen, scientists from the caesar research centre in Bonn, an ...
... Columbia is arguably the most important fossil deposit in ... "Explosion," the rapid flowering of complex life from single-celled ... of shells, teeth and bones, the Burgess Shale preserves ... structuresof animals belonging to Earth,s earliest complex ecosystems a ...
Cached Biology News:The shape of things to come: NIST probes the promise of nanomanufacturing using DNA origami 2Sperm can count 2Mechanism for Burgess Shale-type preservation 2
(Date:7/23/2014)... Quantum Center at Skolkovo) and Mario Ziman (Masaryk ... of Physics in Bratislava, Slovakia) have found a ... through an amplifier and, conversely, when transmitting a ... an article published in the journal Physical ... particles are considered to be the basis of ...
(Date:7/23/2014)... Last year, Formedix celebrated ... global provider of data management solutions for clinical trials. ... system for electronic data capture (EDC) and clinical data ... study execution tools added TrialMaster to its Transform for ... of Transform for TrialMaster, is being released this week, ...
(Date:7/23/2014)... 23, 2014 DuPont Pioneer announced today ... vice president of Agricultural Biotechnology (ABT), effective July 21, ... served most recently as president, chief executive officer and ... leadership in the seed and crop protection industry to ... E. Schickler , president of DuPont Pioneer. “I am ...
(Date:7/23/2014)... PARK, Calif. , July 23, 2014  Sofinnova ... investment firm, today announced the closing of Sofinnova Venture ... million and in excess of the initial fund target ... helping entrepreneurs build successful biotechnology companies. Consistent with recent ... with promising later stage clinical programs, along with select ...
Breaking Biology Technology:Scientists find way to maintain quantum entanglement in amplified signals 2Scientists find way to maintain quantum entanglement in amplified signals 3Scientists find way to maintain quantum entanglement in amplified signals 4Formedix and OmniComm Systems® Partnership Strengthened with the Release of Enhanced TrialMaster® Integration for EDC Build 2Formedix and OmniComm Systems® Partnership Strengthened with the Release of Enhanced TrialMaster® Integration for EDC Build 3DuPont Pioneer Names Neal Gutterson to Lead Agricultural Biotechnology 2DuPont Pioneer Names Neal Gutterson to Lead Agricultural Biotechnology 3Sofinnova Raises $500 Million Biotech Venture Fund 2
... , SAN MARINO, Calif., Aug. 11 ... technology company Viral Genetics (Pink Sheets: VRAL), will address the 4th ... Her presentation will highlight the potential for combining chemotherapy with compounds ... the energy needed to repair chemotherapy induced DNA damage. This repair ...
... SHANGHAI, Aug. 11 /PRNewswire-Asia/ -- WuXi PharmaTech (Cayman) Inc.,(NYSE: ... outsourcing company serving the,pharmaceutical, biotechnology, and medical device industries, ... its financial results for,second-quarter 2009. , ... 2009 Highlights, -- Net revenues totaled ...
... Del., Aug. 11 ParagonRx, a healthcare consulting leader in ... a free Webinar-on-Demand created by the Drug Safety Executive Council ... officers in healthcare companies. , , The ... g onrx.com/experience/webinars/ . , , ...
Cached Biology Technology:Viral Genetics Scientist Presents Potential New Treatment for Drug Resistant Brain Tumors at Aspen Symposium 2Viral Genetics Scientist Presents Potential New Treatment for Drug Resistant Brain Tumors at Aspen Symposium 3WuXi PharmaTech Announces Second-Quarter 2009 Results 2WuXi PharmaTech Announces Second-Quarter 2009 Results 3WuXi PharmaTech Announces Second-Quarter 2009 Results 4WuXi PharmaTech Announces Second-Quarter 2009 Results 5WuXi PharmaTech Announces Second-Quarter 2009 Results 6WuXi PharmaTech Announces Second-Quarter 2009 Results 7WuXi PharmaTech Announces Second-Quarter 2009 Results 8WuXi PharmaTech Announces Second-Quarter 2009 Results 9WuXi PharmaTech Announces Second-Quarter 2009 Results 10WuXi PharmaTech Announces Second-Quarter 2009 Results 11WuXi PharmaTech Announces Second-Quarter 2009 Results 12WuXi PharmaTech Announces Second-Quarter 2009 Results 13WuXi PharmaTech Announces Second-Quarter 2009 Results 14WuXi PharmaTech Announces Second-Quarter 2009 Results 15WuXi PharmaTech Announces Second-Quarter 2009 Results 16