Navigation Links
$1.6 million grant to lead development of resistance-detecting field kit
Date:5/11/2009

Liverpool School of Tropical Medicine (LSTM) has been awarded a 1.1m grant by the US National Institutes of Health to lead a five year project to develop a Field Applicable Screening Tool (FAST) kit to detect resistance to public health insecticides in mosquitoes.

The two principal methods for control of malaria in sub-Saharan Africa are the use of insecticide-treated bednets (ITNs) and indoor residual spraying (IRS) of insecticides. Scientists at LSTM, the Centers for Disease Control and Prevention in the US, Ghana's Biotechnology and Nuclear Agricultural Research Institute and Uganda's National Livestock Resources Research Institute will be working in partnership to identify genes that render malaria-carrying mosquitoes resistant to a range of insecticides that are used for IRS and ITN. At present information on underlying resistance mechanisms of the two most important mosquito species is very limited.

Based upon this knowledge, a rapid and cost-effective DNA-based screening kit will be designed, tested and rolled out for use by control programme staff in the regions of sub-Saharan Africa where malaria and filariasis, a disabling and disfiguring condition also spread by mosquitoes, is endemic. The new screening tools will provide information vital for predicting the success of IRS and ITN programmes.

Project leader Dr Martin Donnelly, Senior Lecturer in Vector Biology at LSTM said: "Malaria control in Africa is reliant upon the use of insecticides against mosquitoes. Therefore if the mosquitoes develop high levels of resistance to these insecticides the public health impact could be devastating. We are proposing to develop DNA-based tests which are sensitive enough to detect resistance when it is at a low level and thereby enable control programme staff to take action to reduce the build up of resistance."

The rollout of FAST kits will be facilitated in collaboration with existing programmes run by IVCC, TDR (a Worl
'/>"/>

Contact: Billy Dean
william.dean@liv.ac.uk
Liverpool School of Tropical Medicine
Source:Eurekalert

Page: 1 2

Related biology news :

1. Structure of 450 million year old protein reveals evolutions steps
2. First orchid fossil puts showy blooms at some 80 million years old
3. SyntheMed Completes $2.8 Million Equity Financing
4. Rutgers Genetics receives $7.8 million for autism research
5. Seattle Childrens Hospital leads $23.7 million NIH grant to study gene repair
6. UD leads $5.3-million research project on rice epigenetics
7. Rutgers high school outreach gets $3 million boost from NSF
8. NIH awards researcher $1.5 million new innovator grant for fruit-fly studies of prion proteins
9. UD leads $5.3-million research project on rice epigenetics
10. $22 million gift from Alfred Taubman launches new biomedical research institute
11. Nanobiosym awarded $2 million DTRA contract
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/6/2015)... TEL AVIV, Israel , May 6, 2015 /PRNewswire/ ... the world,s most established helmet producer, announced today that ... LifeBEAM Smart Helmet, the world,s first bio-sensing cycling helmet ... will be released in two new colors in order ... demand for the product. In addition, LifeBEAM and Lazer ...
(Date:4/27/2015)... April 27, 2015  For more than four decades, ... has been the premier worldwide event for the unmanned ... a must-attend event for any local, national, or trade ... emerging commercial markets and current applications of unmanned technologies. ... this projected $48 billion industry, and how it will ...
(Date:4/27/2015)... LAUDERDALE, Fla. , Apr. 27, 2015 ... of access control and security systems is pleased to ... the company as a consultant and member of its ... is widely known as a thought leader in ... Distance Learning Technology Group, and has published studies and ...
Breaking Biology News(10 mins):LifeBEAM and Lazer Announce Expanded Partnership in Bio-Sensing Sports Gear 2LifeBEAM and Lazer Announce Expanded Partnership in Bio-Sensing Sports Gear 3UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 2UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 3UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 4UNMANNED SYSTEMS 2015: Largest International Conference and Trade Show for the Drone and Unmanned Technology Industry 5Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 2Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 3Profile Solutions Names Medicinal Cannabis, Agriculture and Technology Expert Dr. Gerry Bedore to its Scientific Advisory Board 4
... JOLLA, CAWhen you eat may be just as vital to ... Salk Institute for Biological Studies. Their experiments in mice revealed ... in the liverthe body,s metabolic clearinghouseis mostly controlled by food ... wisdom had it. "If feeding time determines the ...
... gut bacteria bind to the gastrointestinal tract. The protein could be ... be of real benefit to people. , "Probiotics need to interact ... if they attach to surfaces in the gut they are more ... Dr Nathalie Juge from the Institute of Food Research. IFR ...
... NEW YORK (November 24, 2009) -- The Wildlife Conservation Society ... tigers has likely declined significantly due to the rising tide of poaching and ... WCS says the report will help inform Russian officials of what ... ...
Cached Biology News:Feeding the clock 2Feeding the clock 3A sticky solution for identifying effective probiotics 2Report shows dramatic decline in Siberian tigers 2
(Date:5/26/2015)... - Fluorinov Pharma (Fluorinov), a FACIT portfolio company, today ... to its Board of Directors.  His appointment strengthens Fluorinov,s ... Fluorinov accelerates its clinical development activities.  ... pleasure to welcome Luke to the Board of Directors.  ... financial strength and success of multiple organizations," said ...
(Date:5/26/2015)... Just the characterization of being a new breakthrough ... not guarantee immediate acceptance. In particular, a new ... failures is often met with significant skepticism. The ... that is often an unappreciated aspect of scientific innovation. ... has found that building acceptance of its new ...
(Date:5/25/2015)... 25, 2015 Phenome Networks, a ... announced the availability, beginning May 31st, of its next-generation ... Phenome One solidifies Phenome Networks’ lead in the plant ... simple and intuitive breeding workflow based on years of ... customize field design, and more. The new version of ...
(Date:5/22/2015)... May 22, 2015 Knowledgent , ... paper that explores the potential of big data analytics ... paper was developed to help life sciences and healthcare ... data to gain critical business insights. , The life ... of data driven by patient profiling, compliance and regulatory ...
Breaking Biology Technology:Luke M. Beshar Appointed to Fluorinov Pharma Board of Directors 2Luke M. Beshar Appointed to Fluorinov Pharma Board of Directors 3In August Asymmetrex Will Present Details of Its Crowdsourcing Campaign to Determine the Extent of Application of New Technologies for Counting Adult Tissue Stem Cells 2In August Asymmetrex Will Present Details of Its Crowdsourcing Campaign to Determine the Extent of Application of New Technologies for Counting Adult Tissue Stem Cells 3Phenome Networks Announces its Next Generation Plant Breeding Management and Analytics Software 2Phenome Networks Announces its Next Generation Plant Breeding Management and Analytics Software 3New White Paper Explores the Potential of Big Data Analytics in Life Sciences and Healthcare 2
... Odijk, you win. The professor of biotechnology at Delft ... best friend in Rice University,s Matteo Pasquali. ... Scientific Research (CNRS), the University of Bordeaux, France, and ... have settled a long-standing controversy in the field of ...
... N.J., Jan. 7, 2011 Savient Pharmaceuticals, Inc. (Nasdaq: ... activities related to the U.S. launch and commercialization of KRYSTEXXA, ... of chronic gout in adult patients refractory to conventional therapy. ... the promotional launch of KRYSTEXXA in the first quarter of ...
... University of California, Santa Cruz, have identified a key molecule ... bone marrow. The findings, reported in the January issue of ... the safety and efficiency of bone marrow transplants. Bone ... to treat cancers such as lymphoma and leukemia and other ...
Cached Biology Technology:Bendy tubes get around 2Bendy tubes get around 3Savient Pharmaceuticals Provides Business Update 2Savient Pharmaceuticals Provides Business Update 3Savient Pharmaceuticals Provides Business Update 4Savient Pharmaceuticals Provides Business Update 5Savient Pharmaceuticals Provides Business Update 6Stem cell discovery could lead to improved bone marrow transplants 2
... a unique alternative to traditional TBE ... electrophoresis buffers. Bionic Buffer allows for ... times, and high-resolution band separation. -Application: ... after dilution to working 1x concentrations. ...
Fujifilm Pictro-Color Process for sharp, clear reproduction comparable to silver-halide photography. Photorealistic 400 dpi quality. A4 and A5 output....
Sufficient reagents for 50 applications.Mitochondria Isolation Kit Reagent A, 50 ml Mitochondria Isolation Kit Reagent B, 500 l Mitochondria Isolation Kit Reagent C, 70 ml...
... loxP-amp-loxP cassette is designed to allow ... prokaryotic promoter gb2 driving the gene for ... of the Em7 promoter. It mediates higher ... promoter. A synthetic polyadenylation signal terminates the ...
Biology Products: