Navigation Links
$1.6 million grant to lead development of resistance-detecting field kit
Date:5/11/2009

Liverpool School of Tropical Medicine (LSTM) has been awarded a 1.1m grant by the US National Institutes of Health to lead a five year project to develop a Field Applicable Screening Tool (FAST) kit to detect resistance to public health insecticides in mosquitoes.

The two principal methods for control of malaria in sub-Saharan Africa are the use of insecticide-treated bednets (ITNs) and indoor residual spraying (IRS) of insecticides. Scientists at LSTM, the Centers for Disease Control and Prevention in the US, Ghana's Biotechnology and Nuclear Agricultural Research Institute and Uganda's National Livestock Resources Research Institute will be working in partnership to identify genes that render malaria-carrying mosquitoes resistant to a range of insecticides that are used for IRS and ITN. At present information on underlying resistance mechanisms of the two most important mosquito species is very limited.

Based upon this knowledge, a rapid and cost-effective DNA-based screening kit will be designed, tested and rolled out for use by control programme staff in the regions of sub-Saharan Africa where malaria and filariasis, a disabling and disfiguring condition also spread by mosquitoes, is endemic. The new screening tools will provide information vital for predicting the success of IRS and ITN programmes.

Project leader Dr Martin Donnelly, Senior Lecturer in Vector Biology at LSTM said: "Malaria control in Africa is reliant upon the use of insecticides against mosquitoes. Therefore if the mosquitoes develop high levels of resistance to these insecticides the public health impact could be devastating. We are proposing to develop DNA-based tests which are sensitive enough to detect resistance when it is at a low level and thereby enable control programme staff to take action to reduce the build up of resistance."

The rollout of FAST kits will be facilitated in collaboration with existing programmes run by IVCC, TDR (a World Health Organisation programme for research and training in tropical diseases) and PMI (US President's Malaria Initiative).


'/>"/>

Contact: Billy Dean
william.dean@liv.ac.uk
Liverpool School of Tropical Medicine
Source:Eurekalert

Related biology news :

1. Structure of 450 million year old protein reveals evolutions steps
2. First orchid fossil puts showy blooms at some 80 million years old
3. SyntheMed Completes $2.8 Million Equity Financing
4. Rutgers Genetics receives $7.8 million for autism research
5. Seattle Childrens Hospital leads $23.7 million NIH grant to study gene repair
6. UD leads $5.3-million research project on rice epigenetics
7. Rutgers high school outreach gets $3 million boost from NSF
8. NIH awards researcher $1.5 million new innovator grant for fruit-fly studies of prion proteins
9. UD leads $5.3-million research project on rice epigenetics
10. $22 million gift from Alfred Taubman launches new biomedical research institute
11. Nanobiosym awarded $2 million DTRA contract
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/11/2016)...  Vigilant Solutions announces today that its license plate recognition ... Lee,s Summit Police Department to improve ... of a homicide suspect. Kansas City ... square miles and is home to roughly 100,000 residents. ... mobile license plate reader system and also leverages Vigilant,s network ...
(Date:2/9/2016)... 9, 2016 Aware, Inc. (NASDAQ: AWRE ), a ... for its fourth quarter and year ended December 31, 2015.  ... fourth quarter of 2015 was $6.9 million, an increase of 61% ... income in the fourth quarter of 2015 was $2.6 million compared ... --> --> Higher revenue and operating ...
(Date:2/8/2016)... February 8, 2016 Worldcore ... which presents innovation for clients, comfort and unbeatable ... VoiceKey. --> Worldcore is the ... for clients, comfort and unbeatable security, with a ... Worldcore is the first EU-regulated ...
Breaking Biology News(10 mins):
(Date:2/11/2016)... Feb. 11, 2016  Neurocrine Biosciences, Inc. (NASDAQ: NBIX ) ... December 31, 2015. --> --> ... net loss of $29.3 million, or $0.34 loss per share, compared ... share for the same period in 2014. For the year ended ... million, or $1.05 loss per share, as compared to a net ...
(Date:2/11/2016)...  Bioethics International, a not-for-profit organization focused on the ethics ... made accessible to patients around the world, today announced that ... publication of the Good Pharma Scorecard an ... as one of BMJ Open ,s ,Most Popular Articles, ... most frequently read. Ed Sucksmith , assistant editor ...
(Date:2/11/2016)... NY (PRWEB) , ... February ... ... a business-to-business publication dedicated to delivering cutting-edge information focused on the development ... Life Sciences to become a premier sponsor of the 2016 BioProcess International ...
(Date:2/11/2016)... 2016   BioInformant announces the February 2016 ... Products, Opportunities, Tools, and Technologies – Market Size, Segments, ... The first and only ... industry, BioInformant has more than a decade of historical ... by stem cell type. This powerful 175 page global ...
Breaking Biology Technology: