Navigation Links
$1.6 million grant to lead development of resistance-detecting field kit
Date:5/11/2009

Liverpool School of Tropical Medicine (LSTM) has been awarded a 1.1m grant by the US National Institutes of Health to lead a five year project to develop a Field Applicable Screening Tool (FAST) kit to detect resistance to public health insecticides in mosquitoes.

The two principal methods for control of malaria in sub-Saharan Africa are the use of insecticide-treated bednets (ITNs) and indoor residual spraying (IRS) of insecticides. Scientists at LSTM, the Centers for Disease Control and Prevention in the US, Ghana's Biotechnology and Nuclear Agricultural Research Institute and Uganda's National Livestock Resources Research Institute will be working in partnership to identify genes that render malaria-carrying mosquitoes resistant to a range of insecticides that are used for IRS and ITN. At present information on underlying resistance mechanisms of the two most important mosquito species is very limited.

Based upon this knowledge, a rapid and cost-effective DNA-based screening kit will be designed, tested and rolled out for use by control programme staff in the regions of sub-Saharan Africa where malaria and filariasis, a disabling and disfiguring condition also spread by mosquitoes, is endemic. The new screening tools will provide information vital for predicting the success of IRS and ITN programmes.

Project leader Dr Martin Donnelly, Senior Lecturer in Vector Biology at LSTM said: "Malaria control in Africa is reliant upon the use of insecticides against mosquitoes. Therefore if the mosquitoes develop high levels of resistance to these insecticides the public health impact could be devastating. We are proposing to develop DNA-based tests which are sensitive enough to detect resistance when it is at a low level and thereby enable control programme staff to take action to reduce the build up of resistance."

The rollout of FAST kits will be facilitated in collaboration with existing programmes run by IVCC, TDR (a Worl
'/>"/>

Contact: Billy Dean
william.dean@liv.ac.uk
Liverpool School of Tropical Medicine
Source:Eurekalert

Page: 1 2

Related biology news :

1. Structure of 450 million year old protein reveals evolutions steps
2. First orchid fossil puts showy blooms at some 80 million years old
3. SyntheMed Completes $2.8 Million Equity Financing
4. Rutgers Genetics receives $7.8 million for autism research
5. Seattle Childrens Hospital leads $23.7 million NIH grant to study gene repair
6. UD leads $5.3-million research project on rice epigenetics
7. Rutgers high school outreach gets $3 million boost from NSF
8. NIH awards researcher $1.5 million new innovator grant for fruit-fly studies of prion proteins
9. UD leads $5.3-million research project on rice epigenetics
10. $22 million gift from Alfred Taubman launches new biomedical research institute
11. Nanobiosym awarded $2 million DTRA contract
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... N.C. , Dec. 16, 2014 Valencell, a ... its PerformTek biometric technology to industry leaders such as ... accurate, clinically validated, biometric wearable products. These products will ... in Las Vegas . ...
(Date:12/11/2014)... Dec. 09, 2014 Research and Markets ... http://www.researchandmarkets.com/research/twhjll/biometrics_market ) has announced the addition of the ... their offering. One major trend emerging ... advances in technology, it is important to upgrade biometric ...
(Date:12/10/2014)... You,ve been here before: you desperately need to sign into your ... the answer to your secret question. What,s your dog,s birthday? Who ... Labs , a digital infrastructure security company, launches the ... comes with usernames, passwords and PINs – 1U TM ...
Breaking Biology News(10 mins):Valencell PerformTek Biometrics Power the Most Accurate Wearables at CES 2015 2Biometrics Market in the APAC Region 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 2The Password is Finally Dead: Launch of 1U Mobile App Eliminates Need for All Usernames and Passwords 3
... the most rapidly increasing food production system worldwide through ... 2009 issue of BioScience . The assessment, by ... Ann Arbor, notes that despite well-publicized concerns about ... practiced well, be no more damaging to biodiversity than ...
... has worked out how some newly discovered light sensors ... brain. The report appears online this week in ... small number of nerve cells in the retina that ... retinarods and conesmelanopsin-containing cells are not used for seeing ...
... DNA modification in lung cancer, a team of international researchers ... They say that "silencing" of a single gene in lung ... cells, contributing to cancer development and progression. In the ... journal of the American Association for Cancer Research, they also ...
Cached Biology News:Aquaculture's growth seen as continuing 2Bright lights, not-so-big pupils 2Bright lights, not-so-big pupils 3In lung cancer, silencing one crucial gene disrupts normal functioning of genome 2In lung cancer, silencing one crucial gene disrupts normal functioning of genome 3
(Date:1/22/2015)... Cambridge Semantics, the leading provider of smart data solutions driven ... record-breaking year across the board for the company. , ... and our Smart Data solutions, our customers were able to ... to record growth for the company in 2014,” said Alok ...
(Date:1/22/2015)... Protocol Networks brings independent technology consulting to ... independent consultants, Protocol Networks has recently announced its expansion ... years, his company has attracted several clients in The ... well as others. With the success of these engagements, ...
(Date:1/22/2015)... Pipette.com has added the Eppendorf Centrifuge ... of Eppendorf products. , The Eppendorf Centrifuge 5424/5424 R ... R and receive the following:, ,     Free ... Eppendorf Reference 2 ,     3 Free boxes ...
(Date:1/22/2015)... Dr. Greg Leyer of UAS Labs recently ... Supplements Pre-Conference seminar on probiotics in San Diego, CA. ... education conference for health care professionals. This year’s pre-conference seminar ... probiotics in health. Dr. Leyer spoke about the emerging topics ...
Breaking Biology Technology:Cambridge Semantics Announces Record Results for 2014 2Protocol Networks Brings Independent Technology Consulting to the Constitution State 2Eppendorf Announces Promotional Bundle Which Includes: Eppendorf Centrifuge 5424, 3-Pack of Pipettes, and Tips - Available Now at Pipette.com 2
... multi-drug ... resistant infections -, NEW HAVEN, Conn., Jan. ... focused on the,development of novel antibiotics for the treatment of antibiotic-resistant,infections, ... 2 clinical trials. The studies will evaluate the safety and,efficacy of ...
... the pharmaceutical and biotechnology ... strengthens specialist expertise, BOSTON, Jan. 3 Observant ... a passion for research excellence,and a commitment to client ... joined the firm as Vice President. Dr. Hartman,s,research has ...
... are using the tiniest organisms on the planet ,bacteria, as ... study featured in the journal Biotechnology and Bioengineering, lead author ... have gained critical insights that may lead to commercialization of ... can use any kind of waste, such as sewage or ...
Cached Biology Technology:Rib-X Pharmaceuticals Initiates Two Phase 2 Studies for Novel Antibiotic Compound RX-1741 2Rib-X Pharmaceuticals Initiates Two Phase 2 Studies for Novel Antibiotic Compound RX-1741 3Observant LLC Expands Senior Management Team 2Life at the jolt 2Life at the jolt 3Life at the jolt 4
UGT1A6 (D-20)...
... The OEM-EPC is the smallest electronic ... x 60 mm. Parker configured this unit ... science OEM markets. Used in carrier gas ... control, liquid dispensing, and hydro-dynamic focusing, the ...
... The P5T Series Short Stroke Thrust ... stroke applications where mounting envelopes are limited ... wear bands and internal bumpers provide millions ... applications., Choice of composite bushings or ...
... Captiva 96-well Filter Plates are offered ... and 0.45 um depth filter plates are ... LC/MS analysis. Filtration is simple, versatile, and ... columns. The Captiva 10 um glass fiber ...
Biology Products: