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UvrA


Two UvrA proteins form a dimer and they both have ATPase/GTPase activity. The UvrA dimer binds with UvrB and forms a trimer which is able to detect DNA ...
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... acid sequence homology with the E. coli UvrA protein comprising 940 residues. ... defined by the mutation in DB7 represents a homolog of the E. coli uvrA gene. ...
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In vivo, UvrA is present as both a monomer and a dimer, the latter complexing ... In the case of uvrA, uvrB, and uvrD, the derepression is rapid due to the ...
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UVRA Members Year PREZ./SECRETARY ASSIGNMENTS 1 CCBA 1977 YEAR PRESIDENT ... These Guidelines have been revised and agreed upon by all UVRA Town Directors. ...
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uvrA. Information for uvrA, and also upstream and downstream flanking ... Reported regulatory sites for uvrA: Genome coordinates. Source. Transcription factor ...
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Furthermore, the TFO was dissociated from its duplex binding site by UvrA and UvrB. ... In this process, dimerized UvrA binds UvrB in a search for damage-induced ...
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The UvrA protein is the initial damage-recognizing factor in bacterial ... We also show that the UvrA dimer has a high preference of binding the end of a ...
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The UvrA protein on its own binds preferentially to damaged DNA (Seeberg and ... Incubation of substrate G1 with UvrA and wild-type UvrB results in two retarded ...
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The UvrA protein forms a dimer that interacts with UvrB to form a heterotrimeric ... After the release of UvrA, the UvrC protein interacts with the C-terminus of ...
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Strand opening by the UvrA(2)B complex allows dynamic recognition of DNA damage. 18 ... Dimerization of Escherichia coli UvrA and its binding to undamaged and ...
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UvrA and UvrB proteins play key roles in the damage recognition step in the ... (TMR) and Thermus thermophilus HB8 UvrA (ttUvrA) and UvrB (ttUvrB) proteins. ...
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uvrA. FUNCTION: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. ...
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In bacteria, the damage recognition step is carried out by two proteins called UvrA and UvrB. ... UvrA belongs to the ATP-binding cassette (ABC) superfamily of ...
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Immediately 3' of uvrA was an ORF encoding a putative aminopeptidase gene (pepP) ... Here we suggest that uvrA and the nucleotide excision repair pathway are ...
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groups, it was necessary to inactivate the uvrA dependent nucleotide excision repair gene. ... mutant strain deficient in alkA tagA and uvrA, then exposed ...
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Crystal Structure of Bacillus stearothermophilus UvrA Provid... In addition, UvrA contains three zinc modules, the number and ligand sphere of ...
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By the analysis of cells lacking UvrA, we demonstrate ... of UvrA. Although we present evidence ... We also show that UvrA is responsible for methylglyoxal ...
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