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Triplet repeat expansion


Trinucleotide repeat expansion, also known as triplet repeat expansion, is the ... Triplet expansion is caused by slippage during DNA replication. ...
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Aspects of the topic triplet-repeat-expansion are discussed in the following places at Britannica. Assorted References human genetic disease ( in human genetic disease: Triplet repeat expansions ) At least a dozen different disorders are now known to result from triplet repeat expansions in the human genome, and these fall into two groups: (1) those that...
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... dystrophy is caused by expansion of a GCG repeat that places additional alanine ... A second triplet repeat disorder that causes mental retardation was recently ...
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1.1 Triplet Repeat Expansion ... The triplet repeat expansion is sometimes called a dynamic or unstable mutation ... Disease. 1.2 Expansion of Triplet Repeats ...
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Lesson 1: Triplet Repeat Expansion (1 of 3) ... The triplet repeat expansion is sometimes called a dynamic or unstable mutation ...
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Sureshkumar S. A Genetic Defect Caused by a Triplet Repeat Expansion in Arabidopsis thaliana. Science 323:1060 (2009) ... driving triplet repeat contraction ...
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... Triplet Repeats in Noncoding Regions Fragile X syndrome (CGG repeat) Fragile ... is caused by the expansion of a (CGG)n repeat in the 5′ untranslated region ...
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Fragile X Syndrome Triplet Repeat Expansion Disease ... Trinucleotide repeat expansion and human disease. Annu. Rev. Genet. 29:703-728. ...
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Friedreich Ataxia: From GAA Triplet–Repeat Expansion to Frat... the possibility that the GAA triplet-repeat expansion may result in an unusual ...
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Triplet repeat expansion in myotonic dystrophy alters the adjacent chromatin structure. ... is caused by an expansion of a CTG triplet repeat sequence in the 3' ...
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GAA Triplet–Repeat Expansion as an Impediment to Transcription ... Several groups have demonstrated that the GAA-repeat expansion interferes with transcription. ...
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... dominant, was found to result from expansion of a triplet repeat (CAG) as well. ... mutations give rise to repeat expansion RNAs that form nuclear ...
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Recently, the CTG repeat expansion in the DMPK gene causing myotonic dystrophy ... in two patients by triplet repeat-primed PCR (tpPCR) using frequently ...
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The Role of DNA Instability in Triplet Repeat Expansion During in vitro DNA Replication ... DNA instability appeared to induce triplet repeat expansion in vitro. ...
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Abasic Sites Induce Triplet-repeat Expansion during DNA Replication in Vitro ... The occurrence of triplet-repeat expansion (TRE)1 during transmission of genetic ...
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Expansion of a triplet repeat gene segment leads to increased disease severity ... Triplet Repeat Disease - Polyglutamine Diseases ...
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