transversion mutationa
base pair substitution in which the
purine-
pyrimidine orientation on each
DNA strand is reversed; i.e., AT to TA
Source: Jenkins, John B. 1990.
Human Genetics, 2nd Edition. New York: Harper & Row ...
Full article >>>TransversionThe term proposed by Freese ( 1959) for a
mutation caused by the
substitution of a
purine for a
pyrimidine, and vice versa, in
DNA or
RNA. (Cf.
Transition.) ...
Full article >>>Transversion A
base substitution mutation where a
pyrimidine replaces a
purine, or a
purine replaces a
pyrimidine.
Triplet
A
sequence of three
nucleotides. Typically refers to the
codons and the corresponding
genetic code.
Full article >>>transversional mutant A type of
mutation in which a
purine-
pyrimidine base pair is replaced by a
pyrimidine-
purine base pair.
Trapezium trapez = a table.
trauma Injury caused by accident or violence.
Full article >>>Transversion: A
nucleotide substitution in which a
purine replaces a
pyrimidine, or vice versa (e.g., A is changed to T, or T is changed to G) (see
Transition) ...
Full article >>>Instead of
transitions being universally more prevalent than
transversions, as is the case in most genes, A to C
transversions are more frequent than
transitions of C to T. There was also concern about the types of algorithms used.
Full article >>>Substitution mutations from one
pyrimidine to another or one
purine to another (horizontals in diagram) are called
transitions.
Mutations from a
pyrimidine to a
purine, or the reverse (verticals and diagonals in diagram), are called
transversions.
Full article >>>Less common is a
transversion, which exchanges a
purine for a
pyrimidine or a
pyrimidine for a
purine (C/T ↔ A/G).
Full article >>>A
mutation that can be mapped to one specific
site within a
locus. A small
mutation that consists of the replacement (
transition or
transversion); addition; or
deletion (
frameshift) of one or a few
bases.
Full article >>>Since
transition mutations (
purine to
purine or
pyrimidine to
pyrimidine mutations) are more likely than
transversion (
purine to
pyrimidine or vice-versa)
mutations, ...
Full article >>>(If one
purine [A or G] or
pyrimidine [C or T] is replaced by the other, the
substitution is called a
transition. If a
purine is replaced by a
pyrimidine or vice-versa, the
substitution is called a
transversion.) ...
Full article >>>Goldstein and Pollock [Theoretical
Population Biology 45:219-226 (1994)] demonstrated that carefully combining Kimura-type measures [Kimura, J. Mol. Evol., 16:111-120 (1980)] of
sequence distance based on
transversions and
transitions gives a robust ...
Full article >>>DNA is only extremely rarely a direct target of
natural selection rather than changes in the
DNA sequence enduring over generations being a result of the latter; for example, silent
transition-
transversion combinations would alter the
melting point ...
Full article >>>'"/>