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Trans-splicing


Trans-splicing is a special form of RNA processing in eukaryotes where exons from two different primary RNA transcripts are joined end to end and ligated.
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RNA splicing n The process by which base pairs that interrupt the continuity of genetic information in ... Cis- and trans-splicing of mRNAs mediated by ...
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Trans-splicing Trans -splicing is a special form of RNA processing in eukaryotes where exons from two different primary RNA transcripts are joined end
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Intensive study of the physiology, development, behavior, and ecology of the ... SL2 Trans -Splicing and Operons The Discovery of a Second Spliced Leader In 1989, ...
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These specialized trans-splicing reactions are very efficient. In mammals, however, trans-splicing of conventional pre-mRNAs appears to be ...
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Oncogene is one of the world's leading cancer journals. ... In mammals, trans-splicing can be used to reprogram or interfere with specific ...
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Trans-splicing is an unusual process in which two separate RNA strands are ... We use the term 'trans-splicing region' to describe data that contain the ...
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In addition, trans-splicing was not detected in COT of other mammals, such as ... reactions between COT exon 2 from rat and human do not produce trans-splicing. ...
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Trans-splicing appears to reflect an archaic form of RNA processing that is used ... the two events is that trans-splicing is an intermolecular mechanism that ...
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Trans RNA reprograms tau alternative splicing defect in human neurons. ... We designed a pre-trans-splicing molecule containing human tau exons 10 to 13 ...
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In molecular biology, splicing is a modification of an RNA after ... Cis- and trans-splicing of mRNAs mediated by tRNA sequences in eukaryotic cells". Proc. ...
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leader RNA was tested for trans-splicing function in vivo. by mutating the intron. ... within positions 20 –39 permitted accurate trans-splicing in ...
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We study the process of trans-splicing, which controls the production of every ... During the trans-splicing reaction, each of the mRNAs acquires the spliced ...
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Spinal muscular atrophy, a neurodegenerative disorder that causes the weakening of muscles, is the leading cause of ... While trans-splicing (a form of ...
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Destruction of U2, U4, or U6 small nuclear RNA blocks Trans splicing in trypanosome cells ... This trans splicing model predicts that the downstream portion of ...
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There are large numbers of trans-splicing applications, each governed by the ... Such nonspecific trans-splicing can be used to identify alternative splice sites, ...
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