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Topoisomerase


Topoisomerase I solves the problem caused by tension generated by winding/unwinding of DNA. ... See also topoisomerase inhibitor ...
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Eukaryotic type II topoisomerase cannot introduce supercoils; it ... In cancers, the topoisomerase IIalpha is highly expressed in highly proliferating cells. ...
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Inhibition of Human Topoisomerase II in Vitro by Bioactive Benzene Metabolites, ... Topoisomerase-interactive agents make up one recently identified class of ...
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Type I topoisomerase Type I topoisomerases are divided into two structurally and mechanistically distinct topoisomerases: type IA and type IB
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Topoisomerase inhibitor Topoisomerase inhibitors are agents designed to interfere with the action of topoisomerase enzymes [ 1 ] (topoisomerase I and
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The different roles of DNA topoisomerase I and II may indicate an opposing pair ... Soaring Bear's Topoisomerase Site at University of Arizona's College of Pharmacy ...
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Online Shopping at DirectTextBook.com - Save up to 80%, buy or rent. New and used books like DNA Topoisomerase Protocols Volume 1 DNA Topology and Enzymes Methods in...
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Human topoisomerase I is a 100kD protein capable of relaxing positively and ... In normal eukaryotic cells, DNA topoisomerase I does not show relevant ...
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Fruit fly protein-coding gene Top3beta. Represented by 62 ESTs from 17 cDNA libraries. ... protein similar to vertebrate topoisomerase (DNA) III beta (TOP3B) ...
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Fruit fly protein-coding gene Top1. Represented by 93 ESTs from 19 cDNA libraries. ... Topoisomerase I, nuclear enzyme that relieves torsional strain in DNA by ...
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USB Corporation is an established supplier of reliable biochemicals and molecular biology products fueling innovation in both basic research and emerging technology ...
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Information on EC 5.99.1.3 - DNA topoisomerase (ATP-hydrolysing) ... Topoisomerase II. Paramecium bursaria Chlorella virus 1. 661177. Topoisomerase II ...
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Disclosed is a human is a hTopI-α polypeptide and DNA (RNA) encoding such hTopI-α polypeptide. ... Type I topoisomerase recognizes double-stranded DNA but only ...
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Original Article from The New England Journal of Medicine -- DNA Topoisomerase II in Therapy-Related Acute Promyelocytic Leukemia
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of topoisomerase III has no effect on the accumula ... topoisomerase III RuvC double mutants that can be ... type-1 topoisomerase is capable of performing a type-2 ...
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Topoisomerase II is necessary for many biological processes involving double ... In contrast, topoisomerase IIß expression remains stable throughout the cell ...
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The SCOP classification for the Type II DNA topoisomerase superfamily including the families contained in it. Additional information provided includes InterPro ...
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