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Telomere


telomere
the tip of the chromosome arm
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...
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Telomeres
Each eukaryotic chromosome consists of a single molecule of DNA associated with a variety of proteins.
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Telomere shortening
Lagging strand during DNA replication
Telomeres shorten because of the lagging strand phenomenon that is exhibited during DNA replication in eukaryotes only.
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Telomere
The ends of chromosomes. These specialized structures are involved in the replication and stability of linear DNA molecules. See DNA replication.
Related Terms: Chromosome ...
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Telomere
The terminal part of a linear chromosome. Replication of the ends of linear DNA molecules requires specialized enzymes or structures. Often the telomers have a DNA sequence with a single-stranded end that can fold into a hairpin structure.
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telomere
The protective structure at each end of a eukaryotic chromosome. Specifically, the tandemly repetitive DNA (see Repetitive DNA) at the end of the chromosome's DNA molecule.
telophase ...
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Telomeres
Shows the concept of how the ends of chromosomes, the telomeres, shorten each time the cell divides.
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Test Strip—Cedar Creek ...
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Telomeres
Mammalian cells typically divide only about 50 times.
This limit is set by the presence of repeated sequences of DNA at the tips of the chromosomes called telomeres.
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Telomere: The end of a chromosome. This specialized structure is involved in the replication and stability of linear DNA molecules. See DNA replication.
Thymine (T): A nitrogenous base, one member of the base pair AT (adeninethymine).
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telomere A specialized and not well understood nucleic acid structure found at the ends of linear eukaryotic chromosomes. temperate phage A phage whose DNA may be incorporated into the host-cell genome without being expressed.
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Telomere: The natural distal end of a chromosome. Contain some form of simple repeating sequence, usually with a single stranded distal end that may form a hairpin.
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Artificial chromosome A vector constructed from host cell chromosomal elements such as origin of replication, telomeres and centromere (in eukaryotes).
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Liz Blackburn - Australian/US discoverer of telomeres
John Blackwall (1790-1881), British entomologist
Henri Marie Ducrotay de Blainville (1777-1850), French zoologist
Thomas Blakiston, (1832-1891), English naturalist ...
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The ends are called telomeres.
The positions of the centromeres are used to broadly classify chromosomes into three morphological groups: acrocentric (constriction near the top), ...
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A yeast mini-chromosome used for cloning. It has telomeres, a centromere and an autonomous replication sequence (ARS). DNA fragments of 200-500 kb can be cloned using YAC vector.
Other Resources
PubMed Google ...
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Genomic DNA in fragments of 200-500 kb are linked to sequences which allow them to propagate in yeast as a mini-chromosome (including telomeres, a centromere and an ARS - an autonomous replication sequence).
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Telomere. The end of a chromosome. Template. An RNA or single-stranded DNA molecule upon which a complementary nucleotide strand is synthesized. Termination codon.
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