Somatic

somatic cell genetics
using somatic cells to study the genetics of an organism
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...
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Somatic mesoderm
[Gr. somatikos - of or for the body]. The cellular layer on the external side of the coelom; formed from the delamination of lateral plate mesoderm. In conjunction with somites, it will later form body wall and limbs.
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Asexual genetics, involving study of somatic mutation, mitotic crossing-overand segregation.
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...
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Dr. Paul Meltzer, of the National Human Genome Research Institute's Laboratory of Cancer Genetics, defines somatic cells.
related
terms:
cell ...
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Somatic hybrid
A hybrid cell line derived from fusion of cells from different sources. Human/rodent hybrids containing small amount of human genetic material such as a single chromosome are used in human gene mapping.
Related Terms: Hybrid ...
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Somatic Hypermutation (SHM)
Class Switch Recombination (CSR)
T Cells
Alpha/beta (αβ) T cells
Gamma/delta (γδ) T cells ...
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Somatic eukaryotic cells
Main article: mitosis
Eukaryotic cells, conversely, are complex.
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Somatic gene therapy can be broadly split in to two categories: ex vivo (where cells are modified outside the body and then transplanted back in again) and in vivo (where genes are changed in cells still in the body.) Recombination-based approaches ...
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Somatic growth. Growth of the body, exclusive of gametes
Sorting (of a sediment). The range of scatter of particle sizes about the median grain size of a sediment
Space limited. Description of a situation in which space is a limiting resource ...
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Somatic cells: Any cell in the body except sex cells.
Template: a single DNA strand that serves as pattern for building a new second strand.
Thymine (T): A base; one of the molecular components of DNA and RNA. Always bonds with adenine (T-A).
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somatic nervous system
[Gk. soma, body]
The branch of the motor division of the vertebrate peripheral nervous system composed of motor neurons that carry signals to skeletal muscles in response to external stimuli.
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somatic senses All senses except vision, hearing, taste, and smell; include pain, temperature, and pressure.
somatic nervous system The portion of the peripheral nervous system consisting of the motor neuron pathways that innervate skeletal muscles.
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Somatic cell hybridization
In somatic cell hybridization, human cells and rodent tumor cells are fused (hybridized); over time, after the chromosomes mix, human chromosomes are preferentially lost from the hybrid cell until only one or a few remain.
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somatic cell Ordinary body cell; pertaining to or characteristic of a body cell. Any cell other than a germ cell or germ-cell precursor.
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Somatic cell gene therapy. The repair or replacement of a defective gene within somatic tissue. (See Somatic cell.)
Somatotrophin. See Human growth hormone.
Southern blotting. See Southern hybridization.
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somatic cell
any of the cells of a plant or animal except the reproductive cells.
somite
A serial segment of the animal body.
Covered in Lab 12 Animal Diversity II ...
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Somatic hypermutation: A very high frequency of mutational events that occur in specific loci, such as the variable segments of expressed immunoglobulin genes.
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In somatic cells, removal of the 5' most intron is prevented, so that a truncated protein, missing sequence encoded by the last exon, is produced P element pre-mRNA. The resulting truncated protein acts as a repressor of transposition.
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sensory somatic system: a subdivision of the peripheral nervous system that carries impulses from the external environment and the senses.
sepals: modified leaves that enclose and protect a growing bud in flowers.
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archeocyte - somatic cell of sponge that can differentiate into all three other cell types of the organism.
aster - radiating formation of microtubules at each pole of a spindle apparatus, formed during mitosis; comes from word meaning "star." ...
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See Somatic cell. Germ cell (germ line) gene therapy. The repair or re- placement of a defective gene within the gamete-forming tissues, which produces a heritable change in an organism's genetic constitution. GMO. Genetically modified organism.
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Barr body -- the condensed single X-chromosome seen in the nuclei of somatic cells of female mammals. base pair a pair of hydrogen-bonded nitrogenous bases (one purine and one pyrimidine) that join the component strands of the DNA double helix.
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All other cells are somatic cells. globular proteins Soluble proteins with a globular (somewhat rounded) shape. Their axial to diameter ratio is less that 10:1, and usually closer to 1:1.
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Later a mutation occurs in the second copy of the gene in a somatic cell. In that cell both copies of the gene are mutated and the cell develops uncontrolled growth.
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Some organisms are diploid - that is, they have paired homologous chromosomes in their somatic cells, and thus contain two copies of each gene.
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: Also called sex-chromatin body, which represents the inactivated X chromosome in the nucleus of somatic mammalian cells.
Normally only seen in female cells and not in male cells.
It is the result of the process called dosage compensation.
Base ...
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Telomerase is usually found in cells involved in the production of gametes. It is not normally found in somatic cells.
Cyclin-Dependent Kinases
Some cells stop dividing in G1; others stop in G2.
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