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Site-specific Recombinases
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One type of DNA rearrangement is catalyzed by site-specific recombinases.
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AP site Apurinic or apyrimidinic site resulting from the loss of a purine or pyrimidine residue from the DNA.
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...
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Binding site
Specific DNA/RNA sequences a protein or protein complex bind. Some examples of protein binding sites are promoters, ribosome entry sites, and replication origins.
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fragile site
a heritable chromosomal point, visible after a specific staining procedure, where breaks may occur spontaneously
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...
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The active site in many enzymes can be inhibited or suppressed by the presence of another molecule. There are three primary modes of inhibition.
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The active site of an enzyme is the binding site where catalysis occurs. The structure and chemical properties of the active site allow the recognition and binding of the substrate.
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Dr. Eric Green, of the National Human Genome Research Institute's Genome Technology Branch, defines sequence-tagged site (STS).
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Because of the close relationship between biochemistry and medicine, I have included in this glossary a collection of prefixes, ...
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Site within a gene where transcription of RNA begins.
Terminator
The site on a DNA sequence at which transcription and DNA replication stops. Cf. origin.
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Site-specific recombination
Genetic exchange that occurs between particular, short DNA sequences. Site-specific recombination systems do not require RecA.
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Site-directed mutagenesis. The process of introducing spe- cific base-pair mutations into a gene.
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Site-Directed Mutagenesis: The introduction of a mutation, usually a point mutation or an insertion, into a particular location in a cloned DNA fragment.
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Cap site: Two usages: In eukaryotes, the cap site is the position in the gene at which transcription starts, and really should be called the "transcription initiation site".
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Cap site
: The initiation site of transcription in a eukaryotic gene. The initiation of translation of most eukaryotic mRNAs involves recognition of the cap followed by either the first downstream AUG or by a 5' proximal AUG with a consensus sequence ...
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active site: the portion of an enzyme that interacts with the substrate.
active transport: the movement of molecules across a membrane from a region of low concentration to a region of high concentration that requires the expenditure of energy (ATP).
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active site
The specific portion of an enzyme that attaches to the substrate by means of weak chemical bonds.
active transport ...
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sink A site of collection of metabolites, such as sugar; metabolic sinks may exist anywhere in the plant where organic solutes are being transported by the phloem and stored.
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leaves The site of photosynthesis; one of the three major organs in plants.
leukocytes White blood cells; primarily engaged in fighting infection.
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operator - site on DNA at which repressor protein binds to prevent transcription, e.g. in the lac operon.
organogenesis - creation of specific tissues and bodily organs by cell interaction and rearrangement following gastrulation.
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reservoir. The site where a pest population or quantity of inoculum can survive in the absence of a host crop, and from which a new crop may be invaded.
residue management. Management of rice straw and stubble after harvest.
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The exchange of DNA fragments between two DNA molecules or chromatids of paired chromosomes (during crossing over) at the site of identical nucleotide sequences. Homozygote.
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The mitochondrial permeability transition (PT) pore, also called the mitochondrial megachannel, is a multiprotein complex formed at the contact site between the mitochondrial inner and outer membranes, exactly the same location at which Bax, ...
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Year 4 is also believed to mark the beginning of his construction of a new capital, Akhetaten ('Horizon of the Aten'), at the site known today as Amarna.
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through site, district, state, and professional organizations (California Science Project, and NSTA/CSTA/NABT/CUE) conferences.
University of California, Davis Department of Environmental Toxicology Community Outreach Committee Member ...
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As with eukaryotes, the membrane controls the permeability of the cell and is the major site of energy metabolism.
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The promoter and ribosome binding site codes in Eukaryotic DNA are likely to be different than those used by the host organism.
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Restriction enzymes cut DNA wherever their "recognition site" (usually between 4 and 8 bases in length) occurs in the DNA sequence. When there are changes between sequences, a recognition site may appear or be lost.
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Recruitment. The residue of those larvae that have: (1) dispersed; (2) settled at the adult site; (3) made some final movements toward the adult habitat; (4) metamorphosed successfully, and (5) survived to be detected by the observer ...
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nucleus -- Membrane-bound organelle which contains the DNA in the form of chromosomes. It is the site of DNA replication, and the site of RNA synthesis.
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Restriction enzyme cutting site: A specific sequence of DNA at which a particular restriction enzyme cuts the DN A.
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The upper edge of the blastopore produced by invagination during gastrula formation in amphibian embryos; the site toward which surface cells of the gastrula converge and migrate inward along the roof of the blastocoel in the process of involution.
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Epididymis coiled tubules found within the scrotum that store sperm and are the site of their final maturation
(epi = upon over; didym = testes) ...
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restriction nucleases - one of a large number of nucleases that can cleave a DNA molecule at any site where a specific short sequence of nucleotides occurs ...
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In birds and reptiles, it fuses with the chorion to form the chorioallantoic membrane which assists in respiration, and in addition it is the site of storage of nitrogenous wastes.
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