The signal sequence consists of the first portion of the elongating polypeptide chain (so the signal sequence occurs at the amino terminal of the polypeptide). Typical signal sequences contain 15 - 30 amino acids. Full article >>>
The N-terminal signal sequence of the protein is recognized by a signal recognition particle (SRP) while the protein is still being synthesized on the ribosome. Full article >>>
signal sequence An amino-terminal sequence that signals the cellular destination of a newly synthesized protein. signal transduction The process by which an extracellular signal is converted to an intracellular response. Full article >>>
Proteins that are transported by the ER and from there throughout the cell are marked with an address tag that are called a signal sequence. Full article >>>
Recombination reactions only occur at pairs of signal sequences of different types. When the D segment-flanking signals are of the 12 bp type, then the J segmentsignal sequence will have a 23 bp spacer, as will that at the VH gene. Full article >>>
These properties include pI, Mr, presence of secretory signal sequences, presence of transmembrane domains and grand average of hydropathy (GRAVY) scores. Theoretical parameters were evaluated with respect to species and chromosome of origin. Full article >>>
Secreted protein A protein that is exported through the cytoplasmic membrane. Most secreted proteins have specific signal sequences that promote interaction with the export apparatus in the membrane. Segregrate See segregration below. Full article >>>
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