Repressor

repressor
the protein product of a regulator gene that prevents transcription of a gene at some other locus
Source: Jenkins, John B. 1990. Human Genetics, 2nd Edition. New York: Harper & Row ...
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Repressor proteins are coded for by regulator genes. Repressor proteins then attach to a DNA segment known as the operator. By binding to the operator, the repressor protein prevents the RNA polymerase from creating messenger RNA.
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Lac repressor
The lac repressor is an enzyme which stops the metabolism of lactose in bacteria as long as glucose is available.
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The Tryptophan Repressor
In E. coli, the synthesis of the amino acid tryptophan from precursors available to the cell requires 5 enzymes.
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Dr. Richard Morgan, of the National Human Genome Research Institute's Clinical Gene Therapy Branch, defines repressor.
related
terms:
protein, gene ...
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Repressor of Hh signaling
cos2w1 (null) clones have increased Ci levels
cos23 mutation partially suppresses fu vein phenotype just like Su(fu)LP (Preat, 1993)
fu[I]; cos27 flies look like cos27 flies (Preat, 1993) ...
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Repressor
A gene product that negatively regulates gene expression. Usually refers to a DNA-binding protein that inhibits transcription under certain conditions.
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repressor
[L. reprimere, to press back, keep back]
A protein that suppresses the transcription of a gene.
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repressor A compound that binds to and controls the regulator in gene regulation.
reproductive barrier The factors that prevent one sexually propagating population from interbreeding and exchanging genes with another population.
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repressor protein - DNA regulatory protein that binds the operator (a specific DNA sequence) in the absence of the inducing substance (in the case of the lac operon, lactose).
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Repressor. A DNA-binding protein in prokaryotes that blocks gene transcription by binding to the operator.
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The repressor protein is produced by a regulator gene. The region of DNA where the repressor protein binds is the operator site. The promoter site is a region of DNA where RNA polymerase can bind.
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A prokaryotic regulatory element that interacts with a repressor to control the transcription of adjacent structural genes. Organelle. A cell structure that carries out a specialized function in the life of a cell. Origin of replication.
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An example would be the gene coding for cro, a repressor protein. regulatory sequence A DNA sequence involved in regulating the expression of a gene: a promoter or operator. regulon A group of genes that are coordinately regulated.
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Talk a little bit about repressors and activators.
In terms of a biological process, in order to get it going, one always usually thinks of activators.
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Numerous studies have been performed using the relatively laborious method of site-directed mutagenesis and subsequent expression analysis, in order to deduce the identity and nature of cis-regulatory elements (enhancers and repressors) at a ...
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The regulator gene codes for a repressor protein that binds to the operator, obstructing the promoter (thus, transcription) of the structural genes. The regulator does not have to be adjacent to other genes in the operon.
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The term introduced by Jacob, Perrin, Sanchez and Monod (1960) for the site at one end of an operon where a repressor molecule binds to the DNA and thereby inhibits transcription.
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OPERATOR - The site on DNA at which a repressor protein binds to prevent transcription from initiating at the adjacent promoter.
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The resulting truncated protein acts as a repressor of transposition. In germ cells, removal of the intron is allowed. The active transposase is made. This is an example of regulation by differential splice site suppression .
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