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Replication fork


Replication fork
DNA replication unwinds a portion of the DNA helix, forming a fork like structure.
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Replication fork
The region on a replicating doublestranded DNA molecule where synthesis of new DNA is taking place.
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replication fork
A Y-shaped point on a replicating DNA molecule where new strands are growing.
repressible enzyme ...
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Replication Forks
DNA synthesis occurs at numerous different locations on the same DNA molecule (hundreds in a human chromosome).
These form bubbles of replication with a replication fork at the growing edge.
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replication fork - Y-shaped region of replicating DNA molecule at which the two daughter strands are formed and separated
respiratory chain - the name given to the electron-transport chain in the mitochondria ...
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lagging strand The DNA strand that, during replication, must be synthesized in the direction opposite to that in which the replication fork moves. Synthesized via a series of fragments called Okazaki fragments.
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Eukaryotic DNA has many replication forks and also bidirectional synthesis, contrasting to the unidirectional rolling theta prokaryotic method.
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Termination occurs when DNA replication forks meet one another or run to the end of a linear DNA molecule.
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: An enzyme that unwinds the double DNA helix near the replication fork before
DNA polymerase
acts on it. Replication fork moves from 3' to 5' of the leading strand. Unwinding is also necessary for
DNA repair
.
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Then, as the replication fork nears the end of the DNA, there is no longer enough template to continue forming Okazaki fragments. So the 5' end of each newly-synthesized strand cannot be completed.
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This origin of replication is unwound, and the partially unwound strands form a "replication bubble", with one replication fork on either end.
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The DNA-replicating structure at the replication fork consisting of two DNA polymerase III enzymes and a primosome (primase and DNA helicase).
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z ...
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In addition to the Flp-mediated inversion of one replication fork relative to the other, Flp should monomerize concatemers of the two micron plasmid that should result during this mode of replication.
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