Regulatory region

Regulatory region
A DNA base sequence that controls gene expression.
Related Terms: Base sequence ...
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Regulatory region or sequence A DNA base sequence that controls gene expression.
Repetitive DNA Sequences of varying lengths that occur in multiple copies in the genome; it represents much of the human genome.
Reporter gene See: marker ...
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A regulatory region a short distance upstream from the 5' end of a transcription start site that acts as the binding site for RNA polymerase. A region of DNA to which RNA polymerase binds in order to initiate transcription.
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Changes in the regulatory region of the human gene for the V1a receptor have been linked to autism.
Oxytocin
Oxytocin is a peptide of 9 amino acids.
It acts on certain smooth muscles: ...
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Genetic constructs that include regulatory regions targeting gene expression to specific tissues are necessary if the gene product is to be harvested readily.
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Slowed translation through a regulatory region allows formation of a RNA secondary structure that promotes transcription termination. Requires coupled transcription and translation and thus is restricted to prokaryotes.
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Promoters represent critical elements that can work in concert with other regulatory regions (enhancers, silencers, boundary elements /insulators) to direct the level of transcription of a given gene.
Promoter sequences
Prokaryotic promoters ...
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Site-directed mutagenesis is a sophisticated technique that can either change regulatory regions in the promoter of a gene or make subtle codon changes in the open reading frame to identify important amino residues for protein function.
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Effects of point mutations: Point mutations in junk DNA are common but have no effect. Sometimes point mutations in regulatory regions have no effect and sometimes they alter the expression of some genes.
Additions and deletions ...
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