Primary transcript

Primary transcript that is precursor of mature mRNA.
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Primary transcript: When a gene is transcribed in the nucleus, the initial product is the primary transcript, an RNA containing copies of all exons and introns.
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All the primary transcripts produced in the nucleus must undergo processing steps to produce functional RNA molecules for export to the cytosol. We shall confine ourselves to a view of the steps as they occur in the processing of pre-mRNA to mRNA.
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Primary transcripts for some genes can be large. The primary transcripts of the neurexin genes, for instance, are as large as 1.
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cAMP response element binding protein-1 (CREB-1) is thought to be the primary transcription factor in the cascade of gene expression that leads to prolonged structural changes to the synapse enhancing its strength[23].
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Introns are transcribed as part of the normal gene primary transcript, but intron sequences are not found in the functional mRNA. Intron sequences are removed from the primary transcript by a splicing mechanism.
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Extraction of sequence corresponding to the primary transcript of each gene is done by the application program QGB (developed locally). And finally, FASTA is used to compare these sequences with a database of alu elements.
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primary transcript The immediate RNA product of transcription before any posttranscriptional processing reactions. Heterogenous nuclear (hnRNA) is also used. primase An enzyme that synthesizes RNA oligonucleotides used as primers by DNA polymerases.
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