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Phase variation


Phase variation
A mechanism which results in variable expression of surface antigens. An example is the switch between H1 and H2 flagellar antigens by an invertable switch in Salmonella.
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Phase variation: Alternation in the type of flagellum produced by a bacterium.
Phenotype: The observable properties and physical characteristics of of a cell or an organism that is the result of its unique genotype.
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Salmonella typhimurium undergoes antigenic phase variation, producing 2 antigenically different flagellar proteins. The chromosomes in phases 1 and 2 differ in the relative orientation of a small chromosomal segment.
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