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Permutation


Permutation
A permanent and heritable change in a gene that does not have phenotypic consequences (does not cause disease) but predisposes to a future mutation.
Related Terms: Gene ...
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Somatic Hypermutation (SHM)
Class Switch Recombination (CSR)
T Cells
Alpha/beta (αβ) T cells
Gamma/delta (γδ) T cells ...
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Somatic hypermutation: A very high frequency of mutational events that occur in specific loci, such as the variable segments of expressed immunoglobulin genes.
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permutations. Hence, imagine augmenting the above strategy so that the matching probes are arranged one after the other with the nondegenerate regions overlapping but offset by k base pairs.
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See: operation, permutation.
Transformation can be a synonym for metamorphosis and shapeshifting, as in the stories featured on the Transformation Stories Archive.
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Mutations can be caused by copying errors in the genetic material during cell division and by exposure to radiation, chemicals, or viruses, or can occur deliberately under cellular control during the processes such as meiosis or hypermutation.
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As reported in Rao 1998, Volvo has used an evolutionary program called OptiFlex to schedule its million-square-foot factory in Dublin, Virginia, a task that requires handling hundreds of constraints and millions of possible permutations for each ...
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The reason is that there are billions and billions of permutations as to how that folding can occur and we don't understand it well enough to be able to say which is the exact one that occurs. Computationally, it's an extremely difficult problem.
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There are many molecular mechanisms for antigenic variation, including inversion, recombination between multiple casettes, and hypermutation. Antigenic variation occurs in eukaryotic microbes (e.g. Trypanosomes), bacteria (e.g.
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