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Peptide-binding groove


Pockets in the peptide-binding groove of MHC molecules accommodate anchor side ... F and to hold the peptide in the binding groove, rather than a secondary anchor ...
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... of the H-2Kb molecule, which shield the dEV8 peptide in the binding groove. ... is angled away from the peptide binding groove, and CDR3a is displaced to ...
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... of bulky residues in the middle of the floor of the H-2Kk peptide-binding groove. ... accessible surface of the peptide-binding groove, and 20 of them are ...
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... confined to a number of deeper pockets within the peptide binding groove, and ... 3 (residues 24–37) peptide in the binding groove using Sybyl (Tripos, St. ...
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The MHC Class II peptidebinding groove is composed of 2 α-helical regions that ... In vivo, the peptide must enter the binding groove of an empty MHC molecule and ...
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The floor of the peptide-binding groove contains an unusual β bulge, not seen in ... The binding groove of I-Ag7 is unusual at both terminal ends, with a potentially ...
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The floor of the peptide-binding groove contains an unusual β bulge, not seen in ... an antigenic peptide engineered to replace the groove binding region of Ii ...
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... of the peptide looping up and out of the peptide binding groove (pdb entry 1DUZ) ... Just how dynamic is the peptide in the binding groove? ...
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The view is from above the peptide-binding groove. ... a H-2Db-binding groove containing full-length peptide (the corresponding values ...
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... structure of MHC class II molecule has revealed open peptide binding groove. A peptide bound in this groove may flank from one or the other side. ...
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The peptide-binding groove of an HLA molecule consists of two parts, a floor and ... In the class I peptide-binding groove, the ends of the helixes of the 1 and 2 ...
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... two functional MHC complexes having a peptide binding groove, each MHC complex ... bound in the peptide binding groove of the complex, as well as to a method of ...
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... classes is the open-ended peptide-binding groove of MHC class II molecules ... measurable affinity of peptide for the MHC binding groove, in particular the ...
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peptide-binding groove. The crystal structure of the ... ensconced in the MHC peptide-binding groove. Longer peptides are better ...
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The structure of the peptide binding groove, revealed by X-ray crystallography, ... a. Peptide binding groove of class I MHC molecules. ...
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A conservative mutation in a class I MHC molecule outside the peptide binding groove stimu ... interacts with the TCR, and not with the peptide binding groove. ...
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The peptide C- and N-termini are buried deep within the binding groove, and are ... First, the peptide was removed from the binding groove and the empty HLA-A2 ...
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... 11), as they are constrained into the MHCI peptide binding groove, with their N ... The peptide binding groove of MHCII molecules is open, binding peptides in a ...
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