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Penetrance


Penetrance is a term used in genetics describing the proportion of individuals carrying a particular variation of a gene that also express an associated trait (the phenotype). In medical genetics, the penetrance of a disease causing mutation is the proportion of...
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penetrance n. The frequency, under given environmental conditions, with which a specific phenotype is expressed by those individuals with a specific
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Reduced penetrance often occurs with familial cancer syndromes. ... As with reduced penetrance, variable expressivity is probably caused by a ...
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Complete" penetrance means the gene or genes for a trait are expressed in all ... What are reduced penetrance and variable expressivity? ...
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Other High-penetrance Mutations: Identifying germline mutations and somatic mutations is important for our understanding of the cancerogenic process of CRC and in ...
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Low-penetrance Genetic Predisposition: Identifying germline mutations and somatic mutations is important for our understanding of the cancerogenic process of CRC and ...
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deCODEme, 23andMe, and Navigenics all offer services that only test for low penetrance genes, or genes which only sometimes produce an expected trait. Why do
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Online Medical Dictionary and glossary with medical definitions ... Definition of Penetrance. Penetrance: The likelihood a given gene will result in disease. ...
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What is penetrance? Meaning of penetrance medical term. What does penetrance mean? ... penetrance /pen·e·trance/ (pen'ĭ-trins) the frequency with which a heritable ...
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A new study calculates the odds of developing Huntington's Disease with reduced penetrance range CAG counts. ... an age of onset curve and penetrance figures. ...
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This parent with the Pp genotype exhibits reduced penetrance for the P allele. ... Penetrance - the frequency of expression of an allele when it is present in the ...
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Increasing evidence for incomplete penetrance of LRRK2 mutations presented a ... Interestingly, the age-dependent penetrance of the G2019S mutation at age 85 ...
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... risk is caused by disease loci, which include common, low penetrance alleles. ... Search for low penetrance alleles for colorectal cancer through a scan of 1467 ...
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A new US study suggests the link between a genetic mutation and the iron overload disorder haemochromatosis is more tenuous than ... Disagreement on penetrance ...
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Subject: SNP within DYT1 Reduces Penetrance of GAG Deletion. Date: 6/11/2007 ... the normal DYT1 gene greatly reduces penetrance of the GAG-deleted allele in ...
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